ID   3MGH_EHRRG              Reviewed;         188 AA.
AC   Q5FG73;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2005, sequence version 1.
DT   03-AUG-2022, entry version 88.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=ERGA_CDS_07460;
OS   Ehrlichia ruminantium (strain Gardel).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rickettsiales;
OC   Anaplasmataceae; Ehrlichia.
OX   NCBI_TaxID=302409;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Gardel;
RX   PubMed=16547041; DOI=10.1128/jb.188.7.2533-2542.2006;
RA   Frutos R., Viari A., Ferraz C., Morgat A., Eychenie S., Kandassamy Y.,
RA   Chantal I., Bensaid A., Coissac E., Vachiery N., Demaille J., Martinez D.;
RT   "Comparative genomic analysis of three strains of Ehrlichia ruminantium
RT   reveals an active process of genome size plasticity.";
RL   J. Bacteriol. 188:2533-2542(2006).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
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DR   EMBL; CR925677; CAI28198.1; -; Genomic_DNA.
DR   RefSeq; WP_011255820.1; NC_006831.1.
DR   AlphaFoldDB; Q5FG73; -.
DR   SMR; Q5FG73; -.
DR   EnsemblBacteria; CAI28198; CAI28198; ERGA_CDS_07460.
DR   KEGG; erg:ERGA_CDS_07460; -.
DR   HOGENOM; CLU_060471_4_1_5; -.
DR   OMA; LPWRWYL; -.
DR   OrthoDB; 1385409at2; -.
DR   BioCyc; ERUM302409:ERGA_RS03810-MON; -.
DR   Proteomes; UP000000533; Chromosome.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 1.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
DR   TIGRFAMs; TIGR00567; 3mg; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase.
FT   CHAIN           1..188
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_0000265018"
SQ   SEQUENCE   188 AA;  21226 MW;  98CE6C22BDCB0CBE CRC64;
     MYNILKKSFY KQKSLDVASS LLGKMLLFNQ HKGIITETEA YIGQDDQAAH SFHGYTKRTA
     VMFGNPGFSY VYLIYGMYHC LNVVTEPEGF PAAILIRSII LLSKNTPHTK VNGPGKICKI
     LHITKEHNNI DMTANHSFCI CDTNLNIDDY ICTPRIGISK ATDKFWRLVI PNVTSLQYID
     TKLVCTLT