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FADG_BACSU
ID   FADG_BACSU              Reviewed;         576 AA.
AC   O34320; C0H407; Q796K6;
DT   20-JAN-2009, integrated into UniProtKB/Swiss-Prot.
DT   24-NOV-2009, sequence version 2.
DT   25-MAY-2022, entry version 106.
DE   RecName: Full=Uncharacterized protein FadG;
GN   Name=fadG; Synonyms=ykuG; OrderedLocusNames=BSU14071; ORFNames=BSU14070;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RA   Scanlan E., Devine K.M.;
RT   "Sequence of the Bacillus subtilis chromosome from ykuA to cse-15.";
RL   Submitted (NOV-1997) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   SEQUENCE REVISION TO C-TERMINUS.
RX   PubMed=19383706; DOI=10.1099/mic.0.027839-0;
RA   Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A.,
RA   Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.;
RT   "From a consortium sequence to a unified sequence: the Bacillus subtilis
RT   168 reference genome a decade later.";
RL   Microbiology 155:1758-1775(2009).
RN   [4]
RP   GENE NAME, AND INDUCTION.
RC   STRAIN=168;
RX   PubMed=17189250; DOI=10.1074/jbc.m606831200;
RA   Matsuoka H., Hirooka K., Fujita Y.;
RT   "Organization and function of the YsiA regulon of Bacillus subtilis
RT   involved in fatty acid degradation.";
RL   J. Biol. Chem. 282:5180-5194(2007).
CC   -!- INDUCTION: Repressed by FadR in the absence of LCFAs (fatty acids of
CC       14-20 carbon atoms). When LCFAs are present in the medium, they are
CC       converted to long-chain acyl-CoAs, which antagonize FadR as to its
CC       binding to fadR boxes on target DNA and thus derepress transcription.
CC       {ECO:0000269|PubMed:17189250}.
CC   -!- SIMILARITY: Belongs to the FadG family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA10870.1; Type=Erroneous termination; Note=Extended C-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AJ222587; CAA10870.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AL009126; CAX52614.1; -; Genomic_DNA.
DR   PIR; D69865; D69865.
DR   RefSeq; WP_003244990.1; NZ_JNCM01000035.1.
DR   RefSeq; YP_003097723.1; NC_000964.3.
DR   AlphaFoldDB; O34320; -.
DR   SMR; O34320; -.
DR   STRING; 224308.BSU14071; -.
DR   PaxDb; O34320; -.
DR   PRIDE; O34320; -.
DR   EnsemblBacteria; CAX52614; CAX52614; BSU_14071.
DR   GeneID; 8303034; -.
DR   KEGG; bsu:BSU14071; -.
DR   PATRIC; fig|224308.179.peg.1534; -.
DR   eggNOG; COG3409; Bacteria.
DR   InParanoid; O34320; -.
DR   OMA; SFVCDMS; -.
DR   PhylomeDB; O34320; -.
DR   Proteomes; UP000001570; Chromosome.
DR   Gene3D; 1.10.101.10; -; 2.
DR   InterPro; IPR015020; DUF1906.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   InterPro; IPR002477; Peptidoglycan-bd-like.
DR   InterPro; IPR036365; PGBD-like_sf.
DR   InterPro; IPR036366; PGBDSf.
DR   Pfam; PF08924; DUF1906; 1.
DR   Pfam; PF01471; PG_binding_1; 2.
DR   SUPFAM; SSF47090; SSF47090; 2.
DR   SUPFAM; SSF51445; SSF51445; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..576
FT                   /note="Uncharacterized protein FadG"
FT                   /id="PRO_0000360506"
SQ   SEQUENCE   576 AA;  64006 MW;  30DAB86637AFD490 CRC64;
     MDEMVLLTQE WLNETYKGKS GYNSIEENGK TGWKTMYALT RALQLELGIT QTSDSFGPTT
     LRKLKELGPI STSTNSKKNI VKIIQGALYC KGYGPGGLTG TFGQGTKEAI AEMQLHMGLS
     KTDGVVTPKV FKALLNMDSY ILLNGASEKV RSIQQWLNNK YYNRENFYFM PCDGLYSRDT
     QKSLVYAIQY EEGLSDSIAN GNFGPTTQRL IPVLRIGETD EKNSFIHLFQ AALIFNGYNV
     PFDGVYSESV RSKVKAFQSF AKLQQSGTAD FQTWASLLVS TGDPNRKGVA CDSITQITSD
     RAESLKRAGY KIVGRYLTNA PGSTLNKKIQ PGELETILKS GLNVFPIYQT YGGATNYFNK
     EQGKKDAFAA YKAAKEYGFK NNTVIYFAVD YDAYGNDLNN NIIPHFEGIN EIMNGFLGST
     YKIGIYAPRN VCTIVSKKGL AFASFVSGMS TGFSGNLGYP LPYNWAFDQI STITVGNGSG
     MIEIDNDICS GLDNGVNTIN IVPSENKKFF DQIDVLYETA EKYAQMQSDL NNGVKKTQLA
     NELVAQYLRK DDYKGWKWVP TAGQIDPIYR EWAVKR
 
 
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