AIM21_CANAL
ID AIM21_CANAL Reviewed; 848 AA.
AC Q5AP87; A0A1D8PEW4;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 10-MAY-2017, sequence version 2.
DT 03-AUG-2022, entry version 68.
DE RecName: Full=Altered inheritance of mitochondria protein 21;
GN Name=AIM21; OrderedLocusNames=CAALFM_C110090CA;
GN ORFNames=CaO19.12342, CaO19.4878;
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
CC -!- FUNCTION: Involved in mitochondrial migration along actin filaments.
CC {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, actin patch
CC {ECO:0000250}. Note=Cortical actin patches. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the AIM21 family. {ECO:0000305}.
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DR EMBL; CP017623; AOW26640.1; -; Genomic_DNA.
DR RefSeq; XP_723562.2; XM_718469.2.
DR AlphaFoldDB; Q5AP87; -.
DR STRING; 237561.Q5AP87; -.
DR PRIDE; Q5AP87; -.
DR GeneID; 3634817; -.
DR KEGG; cal:CAALFM_C110090CA; -.
DR CGD; CAL0000178029; orf19.12342.
DR VEuPathDB; FungiDB:C1_10090C_A; -.
DR eggNOG; ENOG502S25J; Eukaryota.
DR HOGENOM; CLU_336152_0_0_1; -.
DR InParanoid; Q5AP87; -.
DR OrthoDB; 1596014at2759; -.
DR PRO; PR:Q5AP87; -.
DR Proteomes; UP000000559; Chromosome 1.
DR GO; GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.
PE 3: Inferred from homology;
KW Cytoplasm; Cytoskeleton; Reference proteome.
FT CHAIN 1..848
FT /note="Altered inheritance of mitochondria protein 21"
FT /id="PRO_0000399514"
FT REGION 1..676
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 717..740
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 798..822
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..62
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 63..80
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 100..115
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..167
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 172..231
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 232..289
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 290..304
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 318..358
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 359..379
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 389..406
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 407..421
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 450..525
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 538..552
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 567..610
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 635..651
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 848 AA; 93190 MW; DF9B68FF63EF2A27 CRC64;
MPDSEPLEPL NQESSSNTEQ LKLSTTPNIP ARPQTRPQKQ STTTTTTVPT DQDSTTETSL
EKPLDNPQDE LDELAHEIEK VLSDPVIPPR PQHGSSTKSS ETQTEHKEHD FEPAHPAIPQ
RPTNKKETIQ SEVGDHNNGL ESKSDLKVNK ETSDDSVSTD KDKVHIKPSI PTIPSRPQSR
NLDFSEVDNT KPSTTPSIPA RPQRQSTTTQ DEYKPQASNT PDIVTRPQTK TEKSVSNEEL
DKPGDEPSSK DQDNERHTDD SNASKSILET EKAVAQEEKK AKKSDVDNKP SEPTTSTDSS
TEPTAPARGF RLPLHMQQGS GPISTSTPVA GSEAELNSLN NSNTFGDGEV TPGNSDTKAT
FKNDEDVENE NRTDSSSFDD DMETISQDNE DGEQDRRNRQ ETATEENAQE SEAPQFETTI
IESGETEERD GDDTDSGELY SEQQQNKEKE ETVPATSTPK IPQRPPKKSS LSRATTNDSL
TSLNSTSKPP KPVISKRPTT EESLSNIEPT IPSRPAINQI PSVGESQHEP IVPNRPGNKD
LASSQKDTQV SVKSKPPPPK PKKLSSKIAA FQQQLFNPAN ASSEEDVSST GSKQPESGIR
KRSTENSVLS RFGGKAIPLP GMFNPNQMPK PSISHGEETS DDKEEKQESA TANAPVRRTR
GPRGKKLPKA VADAEVKTES RFAIESGKLW SIEFKKKIVE EKEIISTSVE DLKKPKILSE
NDEAGDESKE TAVENEVIDN PEIPVKDELQ HDVVDVVGHP EKDVVTGLDD DDEDVPPEVN
ERFIKDEEIS NVGVERTIAS ETTTEKHSTD EEEVEEEAEV DSVDIPIRRV AVNTVDSTEV
QKDVEDEP
