ID   AIM21_CANAW             Reviewed;         847 AA.
AC   C4YD35;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 38.
DE   RecName: Full=Altered inheritance of mitochondria protein 21;
GN   Name=AIM21; ORFNames=CAWG_00423;
OS   Candida albicans (strain WO-1) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=294748;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WO-1;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Involved in mitochondrial migration along actin filaments.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, actin patch
CC       {ECO:0000250}. Note=Cortical actin patches. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AIM21 family. {ECO:0000305}.
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DR   EMBL; CH672346; EEQ42221.1; -; Genomic_DNA.
DR   AlphaFoldDB; C4YD35; -.
DR   STRING; 5476.C4YD35; -.
DR   EnsemblFungi; EEQ42221; EEQ42221; CAWG_00423.
DR   VEuPathDB; FungiDB:CAWG_00423; -.
DR   HOGENOM; CLU_336152_0_0_1; -.
DR   OMA; FQQMFNQ; -.
DR   Proteomes; UP000001429; Chromosome 1, Supercontig 1.1.
DR   GO; GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.
DR   InterPro; IPR021582; Aim21.
DR   Pfam; PF11489; Aim21; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Cytoskeleton.
FT   CHAIN           1..847
FT                   /note="Altered inheritance of mitochondria protein 21"
FT                   /id="PRO_0000399515"
FT   REGION          1..675
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          704..740
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          799..818
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        8..61
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..79
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        98..113
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        127..166
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        171..230
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        231..288
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        317..357
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        358..378
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        388..405
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        406..420
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        461..487
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        498..527
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        531..545
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        566..609
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        634..650
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   847 AA;  93145 MW;  23DDF7914824D689 CRC64;
     MPDSEPLEPL NQESSSNTEQ LKLSTTPNIP ARPQTRPQKQ TTTTTTVPTD QDSTTETSLE
     KPLDNPQDEL DELAHEIEKV LSDPVIPPRP EHGSSTKSSE TQTEHKEQDF EPAHPAIPQR
     PTNKKETIQS EVSDHKNGLE SKFDLKVNEE TPADSVSTDK DKVHIKPSIP TIPSRPQSRN
     LDSSEVDNTK PSTTASIPAR PQRQSTSTQD EYKPQASNTP DIPTRPQTKT EKSVSSEELD
     KPGDEPSSKD QDNERYTDDS NASKSILETE KAVAQEEKKA KKSDVDNKPS EPTTSTDSST
     EPAAPARGFR LPLHMQQGSG PISTSTPVAG SEAELNSLNN SNTFGDGEVT PGNSDTKATF
     KNDEDVENEN RTDSSSFDDD METISQDNED GEQDRRNRQE TATEENAQES EAPQFETTII
     ESGETEERDG DDTDSGELYS EQQQNKEKEK IVPATSTPKI PQRPPKKSSL SRATTNDSLT
     SLDSTSKPPK PVIPKRPTTE ESLSNIEPTI PSRPATKKIT SVGESQHEPI VPNRPDNKDL
     ESSQRDTQAS VKSKPPPPKP KKLSSKIAAF QQQLFNPANA SSKEDVSSTG SKQPESGIRK
     RSTENSVLSR FGGKAIPLPG MFNPNQMPKP SISHGEETSD DREEKQESAT ANAPVRRTRG
     PRGKKLPKAV ADAEVKTESR FAIESGKLWS IEFKKKIVEE KEITSTSVED LEKPKILSEN
     DEAGDEGKET AVENEVIDNP EIPVKDELQH DVVDVVGHPE KDVVTGLDDD DEDVPPEVNE
     RFIKDEEISN VGVERTIASE TTTEKHSTDE EEVEEEAVVD SVDIPIRRVA VNIVDSTEVQ
     KDVEDEP