ID   AIM21_CANTT             Reviewed;         824 AA.
AC   C5MBA7;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 33.
DE   RecName: Full=Altered inheritance of mitochondria protein 21;
GN   Name=AIM21; ORFNames=CTRG_03349;
OS   Candida tropicalis (strain ATCC MYA-3404 / T1) (Yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX   NCBI_TaxID=294747;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC MYA-3404 / T1;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Involved in mitochondrial migration along actin filaments.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, actin patch
CC       {ECO:0000250}. Note=Cortical actin patches. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AIM21 family. {ECO:0000305}.
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DR   EMBL; GG692398; EER32924.1; -; Genomic_DNA.
DR   RefSeq; XP_002549052.1; XM_002549006.1.
DR   AlphaFoldDB; C5MBA7; -.
DR   STRING; 5482.XP_002549052.1; -.
DR   EnsemblFungi; EER32924; EER32924; CTRG_03349.
DR   GeneID; 8300305; -.
DR   KEGG; ctp:CTRG_03349; -.
DR   VEuPathDB; FungiDB:CTRG_03349; -.
DR   eggNOG; ENOG502S25J; Eukaryota.
DR   HOGENOM; CLU_336152_0_0_1; -.
DR   OrthoDB; 1596014at2759; -.
DR   Proteomes; UP000002037; Unassembled WGS sequence.
DR   GO; GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..824
FT                   /note="Altered inheritance of mitochondria protein 21"
FT                   /id="PRO_0000399518"
FT   REGION          15..645
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          694..824
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        40..103
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        123..137
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        139..156
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        185..241
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        256..305
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        306..321
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        333..347
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        386..424
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        479..515
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        529..545
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        546..567
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        719..755
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        762..778
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        809..824
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   824 AA;  91126 MW;  B3D68B4C2FF0D0C1 CRC64;
     MTELNEEATV NEIEQEVQEQ QEQVSIPHIP PRPTRHSPPA IDPDQSTSTS NSTNHPVIPQ
     RPTSRPTKSQ ESKIPQQETP QETQELSSSG KDESDSSAKQ NFEIPVIPTR PSRQHSEEPI
     IPPRPQRTTS QEPVIPIRPE STKSHEDKEE KPISEPVIPS RPKSKSNKPV APSRPESSKS
     VEPEVPARPT RDHLTEPEVP LRPVSSREEA KEGLDNLIDQ LEKDLSETVE PSVHAPIEDE
     DESPIEPVPS ASGLRLPSEV DQQQESEIQE ETNAIAEGQL NSETINSSNT FGDGEVTPGN
     STTKTSFKSD EDEDDEHANH LGTGGDSSSF DDDVETISQE QEDHLEEEQQ QEQQQEQEQE
     QERAAPVVQS LGTAIEEDDQ AGGDETDTER AEAPAEEPVK EEPVKEEPVK EEPVKEEPVK
     EGLIKQESKP VIPVIPSRPP KKASLSRSTT EEDSIGLDQS KPNINKPIIP KRPTTESLKS
     GDESTSSQTQ QPSIPVRPTK SNSSTSSGSS ETVTKSKPPP PKPKKLSSKI AAFQQQLFNP
     MKSGSSADED ENKGEGEQPK PRKAVDSSKF LSRFGGNAIP LPGMFNPGQI PMHARPSSTT
     KDDDNDDDKE EQGSSRSVEN APVRRTRGPR GKKLPKAVSE AKVESESKFC LESGELFGLV
     FTKKVEESVD GLNEEEVAHK SLEEEVTEVN VKPEVASKTV EKQEEEDDII DEYEKDDDIV
     EKDEPKSEND VAKEEVIEAK IDESVTVPGE FKEDTKEEEE EKEEEPVHRI AVSTDSRESP
     IEEEEDDDIV IDKTGEEKLN SSNSSLVDVK QEMEDELSKN DEML