ID   AIM21_CLAL4             Reviewed;         648 AA.
AC   C4XXB1;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   03-AUG-2022, entry version 32.
DE   RecName: Full=Altered inheritance of mitochondria protein 21;
GN   Name=AIM21; ORFNames=CLUG_00584;
OS   Clavispora lusitaniae (strain ATCC 42720) (Yeast) (Candida lusitaniae).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Metschnikowiaceae; Clavispora.
OX   NCBI_TaxID=306902;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 42720;
RX   PubMed=19465905; DOI=10.1038/nature08064;
RA   Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA   Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA   Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA   Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA   Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA   Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA   Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA   Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA   Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA   Birren B.W., Kellis M., Cuomo C.A.;
RT   "Evolution of pathogenicity and sexual reproduction in eight Candida
RT   genomes.";
RL   Nature 459:657-662(2009).
CC   -!- FUNCTION: Involved in mitochondrial migration along actin filaments.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, actin patch
CC       {ECO:0000250}. Note=Cortical actin patches. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AIM21 family. {ECO:0000305}.
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DR   EMBL; CH408076; EEQ36461.1; -; Genomic_DNA.
DR   RefSeq; XP_002619425.1; XM_002619379.1.
DR   AlphaFoldDB; C4XXB1; -.
DR   STRING; 306902.C4XXB1; -.
DR   PRIDE; C4XXB1; -.
DR   EnsemblFungi; EEQ36461; EEQ36461; CLUG_00584.
DR   GeneID; 8500385; -.
DR   KEGG; clu:CLUG_00584; -.
DR   VEuPathDB; FungiDB:CLUG_00584; -.
DR   HOGENOM; CLU_422724_0_0_1; -.
DR   InParanoid; C4XXB1; -.
DR   OMA; FQQMFNQ; -.
DR   Proteomes; UP000007703; Unassembled WGS sequence.
DR   GO; GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.
DR   InterPro; IPR021582; Aim21.
DR   Pfam; PF11489; Aim21; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..648
FT                   /note="Altered inheritance of mitochondria protein 21"
FT                   /id="PRO_0000399519"
FT   REGION          1..479
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          511..550
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          571..648
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..16
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        57..132
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        150..190
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        233..259
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        274..289
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        290..319
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        344..380
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        391..406
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        595..618
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        619..638
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   648 AA;  70548 MW;  88F0D34167ED2867 CRC64;
     MDIPRIPQRP KRSKSSEENT PSSTPSSTPA PIVPARPRKN NGAAASSEGS GEFPPIPRRP
     QRKKNIGETD SEADEKPKDA ESDEGWNDSE GKTPEKDIHA ALKENADSDK PDIGDSEAEK
     QPEVDGKDPA LNLEKALEAN SEEAAIPSED VTEDVTKSEE TKSEDIEASV HIEEKVERES
     EVADTKGDIE VDDGIEVDDA KEVPISELSE TDSAFKSEPT DDAANPVSEE AVKPTEPSED
     AEDELVLDRE SKTARESEPL EAEDVEEQHD QAMEKASSVT QIGETPSDAK ISEDTSESNK
     GDEDVKENVL LEESGSEPKD SETGSPFQVE ESAIVPSEGK PPAEVAETSQ TTNKSAESLH
     SEENLTQAKP ATVSDQQPTE KQEPSEQEIP KQESSKQPSK PIVPTRPNKS VPSVPKRPVR
     SVPASSSPES VQESDAKKAP PPKPKKLSSK IAAFQQMFNQ PEAVPTAPQH PKSGKLSSEK
     IGFAANLQNV MGRGIALPGM ANPQMFQRAS TDLEEETADV HAEPEQNPQV SKAPQRARGP
     RGKRLPKAIK ETTVKVEPRF QLRVASLWQV EFNKPKETEK VDDDLEEDYE VEPEFVDSVR
     EPESDKETVA EPETSTKDDS VQTESLSNEE STSELPEAIT TEHVLDSP