ID   AIM21_LACTC             Reviewed;         650 AA.
AC   C5DJ44;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 45.
DE   RecName: Full=Altered inheritance of mitochondria protein 21;
GN   Name=AIM21; OrderedLocusNames=KLTH0F13376g;
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- FUNCTION: Involved in mitochondrial migration along actin filaments.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, actin patch
CC       {ECO:0000250}. Note=Cortical actin patches. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AIM21 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CU928170; CAR24333.1; -; Genomic_DNA.
DR   RefSeq; XP_002554770.1; XM_002554724.1.
DR   AlphaFoldDB; C5DJ44; -.
DR   STRING; 559295.C5DJ44; -.
DR   EnsemblFungi; CAR24333; CAR24333; KLTH0F13376g.
DR   GeneID; 8292994; -.
DR   KEGG; lth:KLTH0F13376g; -.
DR   eggNOG; ENOG502S25J; Eukaryota.
DR   HOGENOM; CLU_421542_0_0_1; -.
DR   InParanoid; C5DJ44; -.
DR   OMA; VICERET; -.
DR   OrthoDB; 1603131at2759; -.
DR   Proteomes; UP000002036; Chromosome F.
DR   GO; GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.
PE   3: Inferred from homology;
KW   Cytoplasm; Cytoskeleton; Reference proteome.
FT   CHAIN           1..650
FT                   /note="Altered inheritance of mitochondria protein 21"
FT                   /id="PRO_0000399522"
FT   REGION          1..148
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          197..529
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          559..650
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        28..52
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        84..111
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        112..136
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        197..213
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        214..298
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        304..336
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        363..386
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        442..463
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        485..512
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   650 AA;  70179 MW;  13EED2902440809B CRC64;
     MQETQDQLEQ MKTMISKPAG RKDYSLMQEE SVPSTPSGST VGSLITAVGQ NEHNKVRNDE
     EATSSASPDG TPSTVDEGDV EESNSDISGV NEQNFENELE TSLAEGKSWH SAQDLNKSHT
     EEPIDDPNED KMSEINLEPS NKGIEKNATV TEKSATILAK ELSATTDVKK KCLRAAKPNE
     LPAEEYCNED LKGAISGLER RTSKPDLETN EIQDAKSLES GIGSSGNVNE VPKQNAKHPM
     DSCQNLEQSA GTTSAEKEAI RALESQSSGT SQASLAKHKS ETNTSIQSST QETAQAPTVY
     EELGSEAERS KSHAQAYKNQ TDEKEMSGEI IKENPENAID DASSPSKEYD TPSFAGKPEE
     GSENLKAPAK DGEPVDSEKK KKNGGTPIEG RPLQSLEGDA PQVPQRPNKR PPPKKPSSKI
     AAFQAMLKQQ QLMDASKTKD KQIDSGNSLL SGKRANITNN LNGIFGLPGM APGMTPGMVP
     PQRPPARQQT GSDGGSQSSE NQTSSQSAAP SGPQRRARGP KGRKLPAHIA NVEKVETSIK
     TNEIQVLKTW SLKFQKISPT CSEKDSEPLK DIPESGVVSP SNPKSMSELN GVPVESDVIC
     ERETDILQNS KNEMNDLEDT NEDNVKEPRQ FSIPTHFDLG ESDANQEESS