ID   FADL_SALTI              Reviewed;         435 AA.
AC   Q8Z4Y8;
DT   20-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   12-DEC-2006, sequence version 2.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Long-chain fatty acid transport protein;
DE   AltName: Full=Outer membrane FadL protein;
DE   AltName: Full=Outer membrane flp protein;
DE   Flags: Precursor;
GN   Name=fadL; OrderedLocusNames=STY2623, t0473;
OS   Salmonella typhi.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=90370;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CT18;
RX   PubMed=11677608; DOI=10.1038/35101607;
RA   Parkhill J., Dougan G., James K.D., Thomson N.R., Pickard D., Wain J.,
RA   Churcher C.M., Mungall K.L., Bentley S.D., Holden M.T.G., Sebaihia M.,
RA   Baker S., Basham D., Brooks K., Chillingworth T., Connerton P., Cronin A.,
RA   Davis P., Davies R.M., Dowd L., White N., Farrar J., Feltwell T.,
RA   Hamlin N., Haque A., Hien T.T., Holroyd S., Jagels K., Krogh A.,
RA   Larsen T.S., Leather S., Moule S., O'Gaora P., Parry C., Quail M.A.,
RA   Rutherford K.M., Simmonds M., Skelton J., Stevens K., Whitehead S.,
RA   Barrell B.G.;
RT   "Complete genome sequence of a multiple drug resistant Salmonella enterica
RT   serovar Typhi CT18.";
RL   Nature 413:848-852(2001).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700931 / Ty2;
RX   PubMed=12644504; DOI=10.1128/jb.185.7.2330-2337.2003;
RA   Deng W., Liou S.-R., Plunkett G. III, Mayhew G.F., Rose D.J., Burland V.,
RA   Kodoyianni V., Schwartz D.C., Blattner F.R.;
RT   "Comparative genomics of Salmonella enterica serovar Typhi strains Ty2 and
RT   CT18.";
RL   J. Bacteriol. 185:2330-2337(2003).
CC   -!- FUNCTION: Involved in translocation of long-chain fatty acids across
CC       the outer membrane. FadL may form a specific channel (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell outer membrane {ECO:0000250}; Multi-pass
CC       membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the OmpP1/FadL family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAO68180.1; Type=Erroneous initiation; Evidence={ECO:0000305};
CC       Sequence=CAD07623.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AL513382; CAD07623.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AE014613; AAO68180.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; NP_456932.1; NC_003198.1.
DR   RefSeq; WP_001766332.1; NZ_WSUR01000045.1.
DR   AlphaFoldDB; Q8Z4Y8; -.
DR   SMR; Q8Z4Y8; -.
DR   STRING; 220341.16503614; -.
DR   PRIDE; Q8Z4Y8; -.
DR   EnsemblBacteria; AAO68180; AAO68180; t0473.
DR   KEGG; stt:t0473; -.
DR   KEGG; sty:STY2623; -.
DR   PATRIC; fig|220341.7.peg.2656; -.
DR   eggNOG; COG2067; Bacteria.
DR   HOGENOM; CLU_035981_0_0_6; -.
DR   OMA; NRYGFTY; -.
DR   Proteomes; UP000000541; Chromosome.
DR   Proteomes; UP000002670; Chromosome.
DR   GO; GO:0009279; C:cell outer membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0006869; P:lipid transport; IEA:UniProtKB-KW.
DR   InterPro; IPR005017; OMPP1/FadL/TodX.
DR   PANTHER; PTHR35093; PTHR35093; 1.
DR   Pfam; PF03349; Toluene_X; 1.
PE   3: Inferred from homology;
KW   Cell outer membrane; Lipid transport; Membrane; Signal; Transmembrane;
KW   Transmembrane beta strand; Transport.
FT   SIGNAL          1..25
FT                   /evidence="ECO:0000250"
FT   CHAIN           26..435
FT                   /note="Long-chain fatty acid transport protein"
FT                   /id="PRO_0000025205"
SQ   SEQUENCE   435 AA;  47491 MW;  3EA86BBAA0BE6CC8 CRC64;
     MSQKTLFTKS ALAVAVAIIS TQAWSAGFQL NEFSSSGLGR AYSGEGAIAD DAGNVSRNPA
     LITMFDRPTF SAGAVYIDPD VNISGTSPSR RTLDADNIAP TAWVPNVHFV APINDQFGWG
     ASITSNYGLA TEFNDTYAGG SVGGTTDLET MNLNLSGAYR LNEAWSFGLG FDAVYARAKI
     ERFAGDLGQL VAAQNPALAP VAGQILSDTK IAHLNGNQWG FGWNAGILYE LDKNNRYALT
     YRSEVKIDFK GNYSSDLPIA INRFNLPIPT ATGGATQSGY LTLNLPEMWE VSGYNRVAPQ
     WAIHYSLAYT SWSQFQELKA KSTAGDTLFE KHEGFKDAYR IALGTTYYYD DNWTFRTGIA
     FDDSPVPAQN RSISIPDQDR FWLSAGTTYA FNKDASVDVG VSYMHGQSVK INEGPYQFES
     EGKAWLFGTN FNYAF