ID   3MGH_ENTFA              Reviewed;         229 AA.
AC   Q833H5;
DT   26-APR-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   03-AUG-2022, entry version 85.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=EF_1978;
OS   Enterococcus faecalis (strain ATCC 700802 / V583).
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
OC   Enterococcus.
OX   NCBI_TaxID=226185;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700802 / V583;
RX   PubMed=12663927; DOI=10.1126/science.1080613;
RA   Paulsen I.T., Banerjei L., Myers G.S.A., Nelson K.E., Seshadri R.,
RA   Read T.D., Fouts D.E., Eisen J.A., Gill S.R., Heidelberg J.F., Tettelin H.,
RA   Dodson R.J., Umayam L.A., Brinkac L.M., Beanan M.J., Daugherty S.C.,
RA   DeBoy R.T., Durkin S.A., Kolonay J.F., Madupu R., Nelson W.C.,
RA   Vamathevan J.J., Tran B., Upton J., Hansen T., Shetty J., Khouri H.M.,
RA   Utterback T.R., Radune D., Ketchum K.A., Dougherty B.A., Fraser C.M.;
RT   "Role of mobile DNA in the evolution of vancomycin-resistant Enterococcus
RT   faecalis.";
RL   Science 299:2071-2074(2003).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
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DR   EMBL; AE016830; AAO81724.1; -; Genomic_DNA.
DR   RefSeq; NP_815654.1; NC_004668.1.
DR   RefSeq; WP_002383132.1; NZ_KE136528.1.
DR   AlphaFoldDB; Q833H5; -.
DR   SMR; Q833H5; -.
DR   STRING; 226185.EF_1978; -.
DR   EnsemblBacteria; AAO81724; AAO81724; EF_1978.
DR   KEGG; efa:EF1978; -.
DR   PATRIC; fig|226185.9.peg.1855; -.
DR   eggNOG; COG2094; Bacteria.
DR   HOGENOM; CLU_060471_2_0_9; -.
DR   OMA; VEAYHHT; -.
DR   Proteomes; UP000001415; Chromosome.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 1.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
DR   TIGRFAMs; TIGR00567; 3mg; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase; Reference proteome.
FT   CHAIN           1..229
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_0000100086"
SQ   SEQUENCE   229 AA;  25762 MW;  E9DA349FA8612962 CRC64;
     MVKEMKETIN IFNTKTTEEV AQYLLGMYLE HETATGVLGG YIVDAEAYLG PDDEAAHSFG
     LRKTPRLQAM YDKPGTIYLY TMHTHLILNM VTQEQGKPQG VMIRAIEPVE GVDKMIENRQ
     GRQGVELTNG PGKLVAALGI DKQLYGQSIF SSSLRLVPEK RKFPKKIEAL PRIGIPNKGR
     WTELPLRYVV AGNPYISKQK RTAVDQIDFG WKDEENEKSN NAHILRGTT