ID   FAEC_ECOLX              Reviewed;         181 AA.
AC   P04738;
DT   13-AUG-1987, integrated into UniProtKB/Swiss-Prot.
DT   13-AUG-1987, sequence version 1.
DT   25-MAY-2022, entry version 81.
DE   RecName: Full=K88 fimbrial protein A;
DE   Flags: Precursor;
GN   Name=faeC;
OS   Escherichia coli.
OG   Plasmid pFM205.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=6086572; DOI=10.1128/jb.159.2.482-487.1984;
RA   Mooi F.R., van Buuren M., Koopman G., Roosendaal B., de Graaf F.K.;
RT   "K88ab gene of Escherichia coli encodes a fimbria-like protein distinct
RT   from the K88ab fimbrial adhesin.";
RL   J. Bacteriol. 159:482-487(1984).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 160-181.
RX   PubMed=2870470; DOI=10.1093/nar/14.6.2443;
RA   Mooi F.R., Claassen I., Bakker D., Kuipers H., de Graaf F.K.;
RT   "Regulation and structure of an Escherichia coli gene coding for an outer
RT   membrane protein involved in export of K88ab fimbrial subunits.";
RL   Nucleic Acids Res. 14:2443-2457(1986).
CC   -!- FUNCTION: Fimbriae (also called pili), polar filaments radiating from
CC       the surface of the bacterium to a length of 0.5-1.5 micrometers and
CC       numbering 100-300 per cell, enable bacteria to colonize the epithelium
CC       of specific host organs.
CC   -!- SUBUNIT: K88 fimbria, 0.1-1 micrometer in length and 7 nanometers in
CC       diameter, is composed of about 100 identical subunits.
CC   -!- SUBCELLULAR LOCATION: Fimbrium. Note=Predominantly located at the tip
CC       of the fimbriae.
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DR   EMBL; X00940; CAA25454.1; -; Genomic_DNA.
DR   EMBL; X03675; CAA27312.1; -; Genomic_DNA.
DR   PIR; I41314; I41314.
DR   RefSeq; WP_000708866.1; NZ_VRVY01000020.1.
DR   AlphaFoldDB; P04738; -.
DR   SMR; P04738; -.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   Gene3D; 2.60.40.1090; -; 1.
DR   InterPro; IPR036937; Adhesion_dom_fimbrial_sf.
DR   InterPro; IPR008966; Adhesion_dom_sf.
DR   InterPro; IPR016372; K88_fimbrial_pA.
DR   PIRSF; PIRSF002967; K88_fimbrial_pA; 1.
DR   SUPFAM; SSF49401; SSF49401; 1.
PE   4: Predicted;
KW   Disulfide bond; Fimbrium; Plasmid; Signal.
FT   SIGNAL          1..21
FT   CHAIN           22..181
FT                   /note="K88 fimbrial protein A"
FT                   /id="PRO_0000009193"
FT   DISULFID        37..84
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   181 AA;  19067 MW;  44EA049DA025D011 CRC64;
     MKKAFLLACV FFLTGGGVSH AAVQKTIFSA DVVASVCHVV VDADSTGNSG RLTFGTYRKS
     TGASVPPRDF TVRLYESGAT VQGCSAFLAG QVATLDFGNP GQLDAAGVVT RGAGDGIRVD
     VRAVDAQADY RGRLTQDNHS VKYPVDFAAK GQFRFRAQPV FPADVKAGEY SGALTFVVTY
     Q