ID   FAEH_ECOLX              Reviewed;         265 AA.
AC   P33782;
DT   01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1994, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=K88 minor fimbrial subunit FaeH;
DE   Flags: Precursor;
GN   Name=faeH;
OS   Escherichia coli.
OG   Plasmid pFM205.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1400188; DOI=10.1128/jb.174.20.6350-6358.1992;
RA   Bakker D., Willemsen P.T.J., Willems R.H., Huisman T.T., Mooi F.R.,
RA   Oudega B., Stegehuis F., de Graaf F.K.;
RT   "Identification of minor fimbrial subunits involved in biosynthesis of K88
RT   fimbriae.";
RL   J. Bacteriol. 174:6350-6358(1992).
CC   -!- FUNCTION: K88 minor fimbrial subunit, plays an essential role in the
CC       biogenesis of the K88 fimbriae. Fimbriae (also called pili), are polar
CC       filaments radiating from the surface of the bacterium to a length of
CC       0.5-1.5 micrometers and numbering 100-300 per cell. They enable
CC       bacteria to colonize the epithelium of specific host organs.
CC   -!- SUBCELLULAR LOCATION: Fimbrium. Note=Located in or along the K88
CC       fimbrial structure.
CC   -!- SIMILARITY: Belongs to the fimbrial K88 protein family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; Z11700; CAA77760.1; -; Genomic_DNA.
DR   EMBL; Z11710; CAA77771.1; -; Genomic_DNA.
DR   PIR; E45725; S24810.
DR   RefSeq; WP_000704731.1; NZ_VRVY01000020.1.
DR   AlphaFoldDB; P33782; -.
DR   SMR; P33782; -.
DR   GO; GO:0009289; C:pilus; IEA:UniProtKB-SubCell.
DR   GO; GO:0007155; P:cell adhesion; IEA:InterPro.
DR   InterPro; IPR003467; Fimbrial_K88.
DR   Pfam; PF02432; Fimbrial_K88; 1.
PE   3: Inferred from homology;
KW   Fimbrium; Plasmid; Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..265
FT                   /note="K88 minor fimbrial subunit FaeH"
FT                   /id="PRO_0000009243"
SQ   SEQUENCE   265 AA;  28108 MW;  0849E833B1602124 CRC64;
     MKITHHYKSL LSAIISVALF YSAAPHADIL DGGEIQFNGF VTDDAPKWTW QISSPDQTWA
     VDTADARTEN GQLVFDLSDK GPLPFLEGYL YEVAERGGPG FTPFITFSSN GRPFAVKEGS
     DTSVQRFRAS VPVRDPETGN VSGQLSFTLN QGMAVSTGKQ EEGASTPSGM SLVSGQSVTD
     VQSGSLPQGL KNRLSALLLM NKGFGNGMSA VDNGQVITQG VLADGRVMNL AAAYASAVSD
     FELRLPAEGT PARWQAGLNV TVTVQ