FAF3_ARATH
ID FAF3_ARATH Reviewed; 288 AA.
AC Q6NMR8;
DT 08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 83.
DE RecName: Full=Protein FANTASTIC FOUR 3;
GN Name=FAF3; OrderedLocusNames=At5g19260; ORFNames=F7K24.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Cheuk R., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (NOV-2003) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Shinn P., Chen H., Cheuk R., Kim C.J., Ecker J.R.;
RT "Arabidopsis ORF clones.";
RL Submitted (FEB-2004) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP FUNCTION, DEVELOPMENTAL STAGE, TISSUE SPECIFICITY, AND DISRUPTION
RP PHENOTYPE.
RC STRAIN=cv. Columbia;
RX PubMed=21176196; DOI=10.1186/1471-2229-10-285;
RA Wahl V., Brand L.H., Guo Y.L., Schmid M.;
RT "The FANTASTIC FOUR proteins influence shoot meristem size in Arabidopsis
RT thaliana.";
RL BMC Plant Biol. 10:285-285(2010).
CC -!- FUNCTION: Able to repress WUS when constitutively overexpressed, but
CC have no effect on CLV3. {ECO:0000269|PubMed:21176196}.
CC -!- TISSUE SPECIFICITY: Expressed in the shoot apex, stamens, young leaves
CC and young siliques, but not in old leaves. Detected in provascular and
CC vascular tissue, but not in the vegetative meristem. In inflorescences,
CC restricted to the vasculature and absent from young flowers, except
CC from anthers. {ECO:0000269|PubMed:21176196}.
CC -!- DEVELOPMENTAL STAGE: Expressed throughout development. Decreased
CC expression in the shoot apex during the transition to flowering.
CC Expressed in developing embryos from the early heart stage until
CC torpedo stage. {ECO:0000269|PubMed:21176196}.
CC -!- DISRUPTION PHENOTYPE: No visible phenotype; due to the redundancy with
CC other FAF genes. {ECO:0000269|PubMed:21176196}.
CC -!- SIMILARITY: Belongs to the fantastic four family. {ECO:0000305}.
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DR EMBL; AC069326; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AF296837; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002688; AED92677.1; -; Genomic_DNA.
DR EMBL; BT010757; AAR23727.1; -; mRNA.
DR EMBL; BT011588; AAS46641.1; -; mRNA.
DR RefSeq; NP_197427.1; NM_121931.4.
DR AlphaFoldDB; Q6NMR8; -.
DR STRING; 3702.AT5G19260.1; -.
DR PaxDb; Q6NMR8; -.
DR PRIDE; Q6NMR8; -.
DR EnsemblPlants; AT5G19260.1; AT5G19260.1; AT5G19260.
DR GeneID; 832046; -.
DR Gramene; AT5G19260.1; AT5G19260.1; AT5G19260.
DR KEGG; ath:AT5G19260; -.
DR Araport; AT5G19260; -.
DR TAIR; locus:2150205; AT5G19260.
DR eggNOG; ENOG502QVU6; Eukaryota.
DR HOGENOM; CLU_053779_0_0_1; -.
DR InParanoid; Q6NMR8; -.
DR OMA; CHQGLQS; -.
DR OrthoDB; 1294944at2759; -.
DR PhylomeDB; Q6NMR8; -.
DR PRO; PR:Q6NMR8; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q6NMR8; baseline and differential.
DR Genevisible; Q6NMR8; AT.
DR InterPro; IPR021410; FAF.
DR PANTHER; PTHR33155; PTHR33155; 1.
DR Pfam; PF11250; FAF; 1.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..288
FT /note="Protein FANTASTIC FOUR 3"
FT /id="PRO_0000405262"
FT DOMAIN 165..217
FT /note="FAF"
FT REGION 48..100
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 146..172
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 222..261
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 61..100
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 226..257
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 288 AA; 32102 MW; BD8C9B1D4CCE42D3 CRC64;
MGTVVYQQGF QSQLNEPRAL RLRLSSPNPH FSQPFGLALK SHLLDSSHAE DTRNRNDDKA
AASPVSDSSG WSSLQSLSSG SSSSTKTTTS SEKESSYYVQ RPSSCRALSD QSLALCTENL
GSESGSDVTD IDELFSLDVQ TKNLGETTTE TRTLKSRKRS VSPSDLPPPL TTMRGFQCIQ
MRPHRENGRL VMTATNAPPR NGCFQADRSN GRLRLSILKD SNEFVENEEE TIEPEETEEY
EEEEEEEEDE DEDEVMGIEN VQVSRRCVQG DRENRGLLNW ESFCVATS
