ID   FAFL_ARATH              Reviewed;         463 AA.
AC   Q0V865; Q8GXQ2; Q9C579;
DT   08-MAR-2011, integrated into UniProtKB/Swiss-Prot.
DT   05-SEP-2006, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Protein FAF-like, chloroplastic;
DE   Flags: Precursor;
GN   OrderedLocusNames=At5g22090; ORFNames=T6G21.200;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130714; DOI=10.1038/35048507;
RA   Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA   Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA   Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA   Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA   Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA   O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA   Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA   Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA   Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA   Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA   Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA   Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA   Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA   Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA   Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA   Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA   McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA   Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA   Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA   Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA   Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA   Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA   Bevan M., Fransz P.F.;
RT   "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL   Nature 408:823-826(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11910074; DOI=10.1126/science.1071006;
RA   Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA   Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA   Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA   Shinagawa A., Shinozaki K.;
RT   "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL   Science 296:141-145(2002).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT   "Arabidopsis ORF Clones.";
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   GENE FAMILY, AND NOMENCLATURE.
RC   STRAIN=cv. Columbia;
RX   PubMed=21176196; DOI=10.1186/1471-2229-10-285;
RA   Wahl V., Brand L.H., Guo Y.L., Schmid M.;
RT   "The FANTASTIC FOUR proteins influence shoot meristem size in Arabidopsis
RT   thaliana.";
RL   BMC Plant Biol. 10:285-285(2010).
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the fantastic four family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAC34502.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AL589883; CAC34502.1; ALT_INIT; Genomic_DNA.
DR   EMBL; CP002688; AED92981.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED92982.1; -; Genomic_DNA.
DR   EMBL; AK118109; BAC42736.1; -; mRNA.
DR   EMBL; BT026355; ABH04462.1; -; mRNA.
DR   RefSeq; NP_001190360.1; NM_001203431.2.
DR   RefSeq; NP_680195.2; NM_147890.4.
DR   AlphaFoldDB; Q0V865; -.
DR   STRING; 3702.AT5G22090.2; -.
DR   iPTMnet; Q0V865; -.
DR   PaxDb; Q0V865; -.
DR   PRIDE; Q0V865; -.
DR   ProteomicsDB; 222376; -.
DR   EnsemblPlants; AT5G22090.1; AT5G22090.1; AT5G22090.
DR   EnsemblPlants; AT5G22090.2; AT5G22090.2; AT5G22090.
DR   GeneID; 832270; -.
DR   Gramene; AT5G22090.1; AT5G22090.1; AT5G22090.
DR   Gramene; AT5G22090.2; AT5G22090.2; AT5G22090.
DR   KEGG; ath:AT5G22090; -.
DR   Araport; AT5G22090; -.
DR   TAIR; locus:504956461; AT5G22090.
DR   eggNOG; ENOG502QUSH; Eukaryota.
DR   HOGENOM; CLU_030144_0_0_1; -.
DR   InParanoid; Q0V865; -.
DR   OMA; NGFSPMK; -.
DR   OrthoDB; 822453at2759; -.
DR   PhylomeDB; Q0V865; -.
DR   PRO; PR:Q0V865; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q0V865; baseline and differential.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
DR   GO; GO:0005737; C:cytoplasm; IDA:TAIR.
DR   GO; GO:0005783; C:endoplasmic reticulum; IDA:TAIR.
DR   GO; GO:0005634; C:nucleus; IDA:TAIR.
DR   GO; GO:0019902; F:phosphatase binding; IDA:TAIR.
DR   GO; GO:0047485; F:protein N-terminus binding; IPI:TAIR.
DR   GO; GO:0009788; P:negative regulation of abscisic acid-activated signaling pathway; IMP:TAIR.
DR   GO; GO:0042326; P:negative regulation of phosphorylation; IGI:TAIR.
DR   GO; GO:0010922; P:positive regulation of phosphatase activity; IDA:TAIR.
DR   InterPro; IPR021410; FAF.
DR   PANTHER; PTHR33155; PTHR33155; 1.
DR   Pfam; PF11250; FAF; 1.
PE   2: Evidence at transcript level;
KW   Chloroplast; Plastid; Reference proteome; Transit peptide.
FT   TRANSIT         1..44
FT                   /note="Chloroplast"
FT                   /evidence="ECO:0000255"
FT   CHAIN           45..463
FT                   /note="Protein FAF-like, chloroplastic"
FT                   /id="PRO_0000405264"
FT   DOMAIN          224..278
FT                   /note="FAF"
FT   REGION          57..135
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          298..320
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        92..107
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        298..318
FT                   /note="Acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        83
FT                   /note="S -> Y (in Ref. 3; BAC42736)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   463 AA;  51446 MW;  B3F432B29BFDABE4 CRC64;
     MMACGLSKSL GLSSSLKKQQ GIVSILGGIS SNTSSAPSLR RTFSADLSSK TWVSQNGFSP
     MKRISSSEKL RPDEEEAEEE SRSGVDIWAQ IQQDKNDKKK EEEIEPGQSD VWSSILSEKK
     KTESSKDTVP PPYVHPLMKR ASSLSEKSLE ICTESLGSET GCDGFSSHAS SETGDAEIEI
     HDETNLVVNV TETKVEEITE TEIVVEQESS IIVPNHIIEL PPGSFPPPIR SLSSQSGSSL
     HMKTRRDNGR LVLEAVSMPS HNNFSAKRQD GRLLLTFAEI SNEPNYDKED EIDSEVQWFD
     EEEEEEEEEE DEEEEAPDEF AYKPNGLLYK MAQKPIPITV HRLAHKPIGV PKRNSRWPMA
     DEFDTKSDLS TPVVHSLPPR PRVAQLARST KPPSTVDDTV GAACFNTCDY SWKSTNTESF
     GPNTKTQFQA QNFVNKSMGD GWINGCKDRR RSLLSVEPFC IAT