ID   FAIM1_BOVIN             Reviewed;         201 AA.
AC   Q0IIF6;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 80.
DE   RecName: Full=Fas apoptotic inhibitory molecule 1;
GN   Name=FAIM;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Hereford; TISSUE=Fetal cerebellum;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays a role as an inducible effector molecule that mediates
CC       Fas resistance produced by surface Ig engagement in B cells.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FAIM1 family. {ECO:0000305}.
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DR   EMBL; BC122668; AAI22669.1; -; mRNA.
DR   RefSeq; NP_001073094.1; NM_001079626.2.
DR   AlphaFoldDB; Q0IIF6; -.
DR   SMR; Q0IIF6; -.
DR   STRING; 9913.ENSBTAP00000031873; -.
DR   PaxDb; Q0IIF6; -.
DR   PRIDE; Q0IIF6; -.
DR   Ensembl; ENSBTAT00000031927; ENSBTAP00000031873; ENSBTAG00000023426.
DR   GeneID; 616795; -.
DR   KEGG; bta:616795; -.
DR   CTD; 55179; -.
DR   VEuPathDB; HostDB:ENSBTAG00000023426; -.
DR   VGNC; VGNC:28709; FAIM.
DR   eggNOG; KOG4352; Eukaryota.
DR   GeneTree; ENSGT00390000007364; -.
DR   HOGENOM; CLU_109086_0_0_1; -.
DR   InParanoid; Q0IIF6; -.
DR   OMA; PQEYRIM; -.
DR   OrthoDB; 1301275at2759; -.
DR   TreeFam; TF314971; -.
DR   Proteomes; UP000009136; Chromosome 1.
DR   Bgee; ENSBTAG00000023426; Expressed in retina and 105 other tissues.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR   GO; GO:0007249; P:I-kappaB kinase/NF-kappaB signaling; IBA:GO_Central.
DR   GO; GO:1902042; P:negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; IBA:GO_Central.
DR   GO; GO:0050769; P:positive regulation of neurogenesis; IBA:GO_Central.
DR   Gene3D; 2.40.128.180; -; 2.
DR   InterPro; IPR010695; FAIM1.
DR   InterPro; IPR038513; FAIM1_dom_sf.
DR   PANTHER; PTHR13088; PTHR13088; 1.
DR   Pfam; PF06905; FAIM1; 1.
PE   2: Evidence at transcript level;
KW   Apoptosis; Cytoplasm; Reference proteome.
FT   CHAIN           1..201
FT                   /note="Fas apoptotic inhibitory molecule 1"
FT                   /id="PRO_0000282882"
SQ   SEQUENCE   201 AA;  22648 MW;  7C88E400016C13B4 CRC64;
     MASGDDSPIF EDDESPPYSL EKMTDLVAVW EVALSDGVHK IEFEHGTTSG KRVVYVDGKE
     VIRKEWMFKL VGKETFCVGA AKTKATINID AVSGFAYEYT LEINGKSLKK YMENRSKTTN
     TWVLHLDSED FRVVLEKDTL DVWCNGKKME TAGEFVDDGT ETHFNIGNHD CYIKAVSSGK
     RKEGIIHSLI VDNREIPEIV E