ID   FAKD1_XENLA             Reviewed;         832 AA.
AC   Q6GQ66;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 49.
DE   RecName: Full=FAST kinase domain-containing protein 1, mitochondrial;
DE   Flags: Precursor;
GN   Name=fastkd1;
OS   Xenopus laevis (African clawed frog).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX   NCBI_TaxID=8355;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Ovary;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May regulate the stability of some mitochondrial mRNA
CC       species. {ECO:0000250|UniProtKB:Q53R41}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q53R41}.
CC   -!- DOMAIN: The RAP domain seems to regulate mitochondrial mRNA levels.
CC       {ECO:0000250|UniProtKB:Q53R41}.
CC   -!- SIMILARITY: Belongs to the FAST kinase family. {ECO:0000305}.
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DR   EMBL; BC072882; AAH72882.1; -; mRNA.
DR   RefSeq; NP_001085520.1; NM_001092051.1.
DR   AlphaFoldDB; Q6GQ66; -.
DR   DNASU; 443946; -.
DR   GeneID; 443946; -.
DR   KEGG; xla:443946; -.
DR   CTD; 443946; -.
DR   Xenbase; XB-GENE-5730785; fastkd1.L.
DR   OrthoDB; 352329at2759; -.
DR   Proteomes; UP000186698; Chromosome 9_10L.
DR   Bgee; 443946; Expressed in egg cell and 19 other tissues.
DR   GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR   GO; GO:0044528; P:regulation of mitochondrial mRNA stability; IEA:InterPro.
DR   InterPro; IPR013579; FAST_2.
DR   InterPro; IPR010622; FAST_Leu-rich.
DR   InterPro; IPR013584; RAP.
DR   Pfam; PF06743; FAST_1; 1.
DR   Pfam; PF08368; FAST_2; 1.
DR   Pfam; PF08373; RAP; 1.
DR   SMART; SM00952; RAP; 1.
DR   PROSITE; PS51286; RAP; 1.
PE   2: Evidence at transcript level;
KW   Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000305"
FT   CHAIN           ?..832
FT                   /note="FAST kinase domain-containing protein 1,
FT                   mitochondrial"
FT                   /id="PRO_0000284712"
FT   DOMAIN          765..825
FT                   /note="RAP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00619"
SQ   SEQUENCE   832 AA;  95378 MW;  429DFAA5D226F584 CRC64;
     MFRWSCAHRL SRSLCQTRFL STDPLLDQLK ICISEDQVFQ LVGKNKARLS VTHVGHAINL
     LWKFQKEKPR MLRTIDQVRG HPEFIALRIL AENKIEFMED NALVEILYNI LRFSVEPHDS
     LVQQLVMEGW RRLERFNLKE ISKFAVCLGE QHMHMSPLMG HIASIVDGIL DDVQDARILS
     SLMVNIHGVI TPMLRDRLVD KADSLMDTLD VSHFNHPRRI VQFLRNMKHT YRPLLEKCNN
     AFLQNIGQMD PENLSIIIGL YQSLQYNNSE FRLMARNRLI EMVDQCNNVA SYTKLFAALG
     PMAGQETREK LEEGILTMVD GMNPNQLLAV LGTMEEMECR NTLLIARIAS LLQKYLGIYR
     PVELARITQA IVNLRCQTPE LFSMLQKILE RNLKSSFIPG DVAMLARVIS SLPAARVDEE
     VFSKVDAILP QCSLSDLSSL ALAIVKWVRT EQPSRYSTSG GLGNLLHKLN TCGHERITKI
     DKIDLFLEEL KYITGDWLEE VLLKDAISTC ERLIDQITWK NLPEFALFIT RTNYLCAPVL
     NKIASVATED ITKIHYNATY AILLPFVVLN YEPPNGEAFF DACIQHVLPH LNSLDPHLVV
     LLAYSLALAE YFPEELIKAV FNIDFLGRLD AQLETFSSTL NLRIRLRLME LNRAVCLECP
     EFQIPWFHDR YCKQLQHRAN AGISSVQRQI HQLLGEILGG INYAKVSVMT PYYHTIDFEC
     ILDKNKKPIL YLDQNVLSAD LSKVQWGNGG QLQETKSLPP GAQRVAIEFL DSKAFSKNSS
     NIKGEYMMKK RHLEILGYHV LQISSLEWNS MELSTKDAWM DYLRKRIFTD DL