ID   FAKD1_XENTR             Reviewed;         832 AA.
AC   Q28DE0;
DT   17-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 56.
DE   RecName: Full=FAST kinase domain-containing protein 1, mitochondrial;
DE   Flags: Precursor;
GN   Name=fastkd1; ORFNames=TEgg089k23.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Egg;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (OCT-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: May regulate the stability of some mitochondrial mRNA
CC       species. {ECO:0000250|UniProtKB:Q53R41}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion {ECO:0000250|UniProtKB:Q53R41}.
CC   -!- DOMAIN: The RAP domain seems to regulate mitochondrial mRNA levels.
CC       {ECO:0000250|UniProtKB:Q53R41}.
CC   -!- SIMILARITY: Belongs to the FAST kinase family. {ECO:0000305}.
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DR   EMBL; CR855565; CAJ83739.1; -; mRNA.
DR   RefSeq; NP_001039188.1; NM_001045723.1.
DR   AlphaFoldDB; Q28DE0; -.
DR   STRING; 8364.ENSXETP00000017468; -.
DR   PaxDb; Q28DE0; -.
DR   GeneID; 734038; -.
DR   KEGG; xtr:734038; -.
DR   CTD; 79675; -.
DR   Xenbase; XB-GENE-5730765; fastkd1.
DR   eggNOG; ENOG502QQ64; Eukaryota.
DR   InParanoid; Q28DE0; -.
DR   OrthoDB; 352329at2759; -.
DR   Proteomes; UP000008143; Chromosome 9.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0005759; C:mitochondrial matrix; IBA:GO_Central.
DR   GO; GO:0005739; C:mitochondrion; ISS:UniProtKB.
DR   GO; GO:0035770; C:ribonucleoprotein granule; IBA:GO_Central.
DR   GO; GO:0003723; F:RNA binding; IBA:GO_Central.
DR   GO; GO:0000963; P:mitochondrial RNA processing; IBA:GO_Central.
DR   GO; GO:0044528; P:regulation of mitochondrial mRNA stability; IBA:GO_Central.
DR   InterPro; IPR013579; FAST_2.
DR   InterPro; IPR010622; FAST_Leu-rich.
DR   InterPro; IPR013584; RAP.
DR   Pfam; PF06743; FAST_1; 1.
DR   Pfam; PF08368; FAST_2; 1.
DR   Pfam; PF08373; RAP; 1.
DR   SMART; SM00952; RAP; 1.
DR   PROSITE; PS51286; RAP; 1.
PE   2: Evidence at transcript level;
KW   Mitochondrion; Reference proteome; Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000305"
FT   CHAIN           ?..832
FT                   /note="FAST kinase domain-containing protein 1,
FT                   mitochondrial"
FT                   /id="PRO_0000284713"
FT   DOMAIN          765..825
FT                   /note="RAP"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00619"
SQ   SEQUENCE   832 AA;  95010 MW;  4266B22A321FE184 CRC64;
     MFRWSCAFRL SRSLLQTRFL STDPLLDQFK ICLSEDQVFQ LVGKNKARLS VTHVGYAINL
     LWQFQKEKPR MLRTIGQVRG HPEFIALRIL AENKIEFMDD KALVEILYNI LRFNLEAHDS
     LVQQLVMEGW RRLERFNLTA LSKFAVCLVE QHMNMSPLMG RIASIVDGTL DDVQDARILS
     SLMVSIYGVI SPTLRDRLVD KADSLVDTLD VSHFNHPRRI VQFLRNMKYT YRPLLEKCNS
     VFLQNVGQMD PENLSIIIGL YQSLQFNNAE FRLMARARLI ETMDQCSDVA SYTKLFAALG
     PMAGQDIREK LEEGILTMAD EMNPTQLLAI LGTMEEMECR NTLLIAKISS LLQKYLESYR
     PVELARITQA IVTLRCQTPE LFSMLQKILE RLLKSSFIPA DVSMLARVIS TLPAARVDEE
     ILSKVDAILP QCSLSDLSSL ALAIVKWVRT DQPSRSSTSG GLGNLLLKLN TCGRERIAKI
     DKIDLFLDEL KYTTGDWLEE VLLKDTISTC ERLIDQVTWK NVPEFALFIT RTNYLCAQVL
     DKIALVATED ITKIHYSATY ATLLPFVVLN YDPPNGEAFF DACIQHFLPH LNSFDPHLVV
     LLAYSLALAE YFPEELIKAV FNVDFLGRLD AQLETFSSAL NMRIRLRLME LNRAVCLECP
     EFQIPWFHDR YCQQLQHRAN GGISSVQRQI HQLLGEILGG INYAKVSVMT PYYHAIDFEC
     ILDKNKKPIP YLDQNVLSAD LSKVQWGNGG PLQETKSLPP GAQRVAIEFL DSKAFSKNSS
     NIKGEYVMKK RHLEILGYHV VQIASFEWNS MELSTKDAWI DYLRKRIFAD DV