ID   FAM3C_XENTR             Reviewed;         229 AA.
AC   B0BLS9;
DT   10-AUG-2010, integrated into UniProtKB/Swiss-Prot.
DT   26-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 51.
DE   RecName: Full=Protein FAM3C;
DE   Flags: Precursor;
GN   Name=fam3c;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (JAN-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in retinal laminar formation. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the FAM3 family. {ECO:0000305}.
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DR   EMBL; BC158148; AAI58149.1; -; mRNA.
DR   RefSeq; NP_001017106.2; NM_001017106.3.
DR   AlphaFoldDB; B0BLS9; -.
DR   SMR; B0BLS9; -.
DR   STRING; 8364.ENSXETP00000049183; -.
DR   PaxDb; B0BLS9; -.
DR   Ensembl; ENSXETT00000049183; ENSXETP00000049183; ENSXETG00000022730.
DR   GeneID; 549860; -.
DR   KEGG; xtr:549860; -.
DR   CTD; 10447; -.
DR   Xenbase; XB-GENE-943493; fam3c.
DR   eggNOG; ENOG502QQR8; Eukaryota.
DR   HOGENOM; CLU_099478_0_0_1; -.
DR   InParanoid; B0BLS9; -.
DR   OMA; EINVEFK; -.
DR   OrthoDB; 1295040at2759; -.
DR   PhylomeDB; B0BLS9; -.
DR   TreeFam; TF353414; -.
DR   Reactome; R-XTR-114608; Platelet degranulation.
DR   Proteomes; UP000008143; Chromosome 3.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000022730; Expressed in egg cell and 12 other tissues.
DR   GO; GO:0005615; C:extracellular space; IBA:GO_Central.
DR   GO; GO:0045721; P:negative regulation of gluconeogenesis; IEA:InterPro.
DR   CDD; cd13940; ILEI_FAM3C; 1.
DR   InterPro; IPR039220; FAM3.
DR   InterPro; IPR039219; FAM3C.
DR   InterPro; IPR039477; ILEI/PANDER_dom.
DR   InterPro; IPR039475; ILEI_FAM3C.
DR   PANTHER; PTHR14592; PTHR14592; 1.
DR   PANTHER; PTHR14592:SF10; PTHR14592:SF10; 1.
DR   Pfam; PF15711; ILEI; 1.
PE   2: Evidence at transcript level;
KW   Developmental protein; Disulfide bond; Reference proteome; Secreted;
KW   Signal.
FT   SIGNAL          1..24
FT                   /evidence="ECO:0000255"
FT   CHAIN           25..229
FT                   /note="Protein FAM3C"
FT                   /id="PRO_0000395985"
FT   DISULFID        59..87
FT                   /evidence="ECO:0000250"
FT   DISULFID        65..222
FT                   /evidence="ECO:0000250"
SQ   SEQUENCE   229 AA;  25098 MW;  18B326E113F80B8B CRC64;
     MRIAGAIKFV IAVALFLLTF YVISQVFEIK MYSNLGNIFA RSAPDTVAHP TTKAPRYRCG
     ISKVCPEKHF AFKIASGAAN VVGPKICVDD NILMSGVKNN VGRGINTALV NGKTGALIET
     TYHDLWGGEV GPFIEFLKKI PDGTIVLMAT YDDGATKLND DARKRIAELG SSLISVLAFR
     DNWVFVGGKG IKTKSPFEQH IKNNKDTNKY EGWPEVVEME GCIPQKINE