FAM9B_HUMAN
ID FAM9B_HUMAN Reviewed; 186 AA.
AC Q8IZU0; Q0IJ68; Q8N7Z8;
DT 25-MAR-2003, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 137.
DE RecName: Full=Protein FAM9B;
GN Name=FAM9B;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1), TISSUE SPECIFICITY, AND SUBCELLULAR
RP LOCATION.
RX PubMed=12213195; DOI=10.1006/geno.2002.6834;
RA Martinez-Garay I., Jablonka S., Sutajova M., Steuernagel P., Gal A.,
RA Kutsche K.;
RT "A new gene family (FAM9) of low-copy repeats in Xp22.3 expressed
RT exclusively in testis: implications for recombinations in this region.";
RL Genomics 80:259-267(2002).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC TISSUE=Testis;
RX PubMed=14702039; DOI=10.1038/ng1285;
RA Ota T., Suzuki Y., Nishikawa T., Otsuki T., Sugiyama T., Irie R.,
RA Wakamatsu A., Hayashi K., Sato H., Nagai K., Kimura K., Makita H.,
RA Sekine M., Obayashi M., Nishi T., Shibahara T., Tanaka T., Ishii S.,
RA Yamamoto J., Saito K., Kawai Y., Isono Y., Nakamura Y., Nagahari K.,
RA Murakami K., Yasuda T., Iwayanagi T., Wagatsuma M., Shiratori A., Sudo H.,
RA Hosoiri T., Kaku Y., Kodaira H., Kondo H., Sugawara M., Takahashi M.,
RA Kanda K., Yokoi T., Furuya T., Kikkawa E., Omura Y., Abe K., Kamihara K.,
RA Katsuta N., Sato K., Tanikawa M., Yamazaki M., Ninomiya K., Ishibashi T.,
RA Yamashita H., Murakawa K., Fujimori K., Tanai H., Kimata M., Watanabe M.,
RA Hiraoka S., Chiba Y., Ishida S., Ono Y., Takiguchi S., Watanabe S.,
RA Yosida M., Hotuta T., Kusano J., Kanehori K., Takahashi-Fujii A., Hara H.,
RA Tanase T.-O., Nomura Y., Togiya S., Komai F., Hara R., Takeuchi K.,
RA Arita M., Imose N., Musashino K., Yuuki H., Oshima A., Sasaki N.,
RA Aotsuka S., Yoshikawa Y., Matsunawa H., Ichihara T., Shiohata N., Sano S.,
RA Moriya S., Momiyama H., Satoh N., Takami S., Terashima Y., Suzuki O.,
RA Nakagawa S., Senoh A., Mizoguchi H., Goto Y., Shimizu F., Wakebe H.,
RA Hishigaki H., Watanabe T., Sugiyama A., Takemoto M., Kawakami B.,
RA Yamazaki M., Watanabe K., Kumagai A., Itakura S., Fukuzumi Y., Fujimori Y.,
RA Komiyama M., Tashiro H., Tanigami A., Fujiwara T., Ono T., Yamada K.,
RA Fujii Y., Ozaki K., Hirao M., Ohmori Y., Kawabata A., Hikiji T.,
RA Kobatake N., Inagaki H., Ikema Y., Okamoto S., Okitani R., Kawakami T.,
RA Noguchi S., Itoh T., Shigeta K., Senba T., Matsumura K., Nakajima Y.,
RA Mizuno T., Morinaga M., Sasaki M., Togashi T., Oyama M., Hata H.,
RA Watanabe M., Komatsu T., Mizushima-Sugano J., Satoh T., Shirai Y.,
RA Takahashi Y., Nakagawa K., Okumura K., Nagase T., Nomura N., Kikuchi H.,
RA Masuho Y., Yamashita R., Nakai K., Yada T., Nakamura Y., Ohara O.,
RA Isogai T., Sugano S.;
RT "Complete sequencing and characterization of 21,243 full-length human
RT cDNAs.";
RL Nat. Genet. 36:40-45(2004).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=15772651; DOI=10.1038/nature03440;
RA Ross M.T., Grafham D.V., Coffey A.J., Scherer S., McLay K., Muzny D.,
RA Platzer M., Howell G.R., Burrows C., Bird C.P., Frankish A., Lovell F.L.,
RA Howe K.L., Ashurst J.L., Fulton R.S., Sudbrak R., Wen G., Jones M.C.,
RA Hurles M.E., Andrews T.D., Scott C.E., Searle S., Ramser J., Whittaker A.,
RA Deadman R., Carter N.P., Hunt S.E., Chen R., Cree A., Gunaratne P.,
RA Havlak P., Hodgson A., Metzker M.L., Richards S., Scott G., Steffen D.,
RA Sodergren E., Wheeler D.A., Worley K.C., Ainscough R., Ambrose K.D.,
RA Ansari-Lari M.A., Aradhya S., Ashwell R.I., Babbage A.K., Bagguley C.L.,
RA Ballabio A., Banerjee R., Barker G.E., Barlow K.F., Barrett I.P.,
RA Bates K.N., Beare D.M., Beasley H., Beasley O., Beck A., Bethel G.,
RA Blechschmidt K., Brady N., Bray-Allen S., Bridgeman A.M., Brown A.J.,
RA Brown M.J., Bonnin D., Bruford E.A., Buhay C., Burch P., Burford D.,
RA Burgess J., Burrill W., Burton J., Bye J.M., Carder C., Carrel L.,
RA Chako J., Chapman J.C., Chavez D., Chen E., Chen G., Chen Y., Chen Z.,
RA Chinault C., Ciccodicola A., Clark S.Y., Clarke G., Clee C.M., Clegg S.,
RA Clerc-Blankenburg K., Clifford K., Cobley V., Cole C.G., Conquer J.S.,
RA Corby N., Connor R.E., David R., Davies J., Davis C., Davis J., Delgado O.,
RA Deshazo D., Dhami P., Ding Y., Dinh H., Dodsworth S., Draper H.,
RA Dugan-Rocha S., Dunham A., Dunn M., Durbin K.J., Dutta I., Eades T.,
RA Ellwood M., Emery-Cohen A., Errington H., Evans K.L., Faulkner L.,
RA Francis F., Frankland J., Fraser A.E., Galgoczy P., Gilbert J., Gill R.,
RA Gloeckner G., Gregory S.G., Gribble S., Griffiths C., Grocock R., Gu Y.,
RA Gwilliam R., Hamilton C., Hart E.A., Hawes A., Heath P.D., Heitmann K.,
RA Hennig S., Hernandez J., Hinzmann B., Ho S., Hoffs M., Howden P.J.,
RA Huckle E.J., Hume J., Hunt P.J., Hunt A.R., Isherwood J., Jacob L.,
RA Johnson D., Jones S., de Jong P.J., Joseph S.S., Keenan S., Kelly S.,
RA Kershaw J.K., Khan Z., Kioschis P., Klages S., Knights A.J., Kosiura A.,
RA Kovar-Smith C., Laird G.K., Langford C., Lawlor S., Leversha M., Lewis L.,
RA Liu W., Lloyd C., Lloyd D.M., Loulseged H., Loveland J.E., Lovell J.D.,
RA Lozado R., Lu J., Lyne R., Ma J., Maheshwari M., Matthews L.H.,
RA McDowall J., McLaren S., McMurray A., Meidl P., Meitinger T., Milne S.,
RA Miner G., Mistry S.L., Morgan M., Morris S., Mueller I., Mullikin J.C.,
RA Nguyen N., Nordsiek G., Nyakatura G., O'dell C.N., Okwuonu G., Palmer S.,
RA Pandian R., Parker D., Parrish J., Pasternak S., Patel D., Pearce A.V.,
RA Pearson D.M., Pelan S.E., Perez L., Porter K.M., Ramsey Y., Reichwald K.,
RA Rhodes S., Ridler K.A., Schlessinger D., Schueler M.G., Sehra H.K.,
RA Shaw-Smith C., Shen H., Sheridan E.M., Shownkeen R., Skuce C.D.,
RA Smith M.L., Sotheran E.C., Steingruber H.E., Steward C.A., Storey R.,
RA Swann R.M., Swarbreck D., Tabor P.E., Taudien S., Taylor T., Teague B.,
RA Thomas K., Thorpe A., Timms K., Tracey A., Trevanion S., Tromans A.C.,
RA d'Urso M., Verduzco D., Villasana D., Waldron L., Wall M., Wang Q.,
RA Warren J., Warry G.L., Wei X., West A., Whitehead S.L., Whiteley M.N.,
RA Wilkinson J.E., Willey D.L., Williams G., Williams L., Williamson A.,
RA Williamson H., Wilming L., Woodmansey R.L., Wray P.W., Yen J., Zhang J.,
RA Zhou J., Zoghbi H., Zorilla S., Buck D., Reinhardt R., Poustka A.,
RA Rosenthal A., Lehrach H., Meindl A., Minx P.J., Hillier L.W., Willard H.F.,
RA Wilson R.K., Waterston R.H., Rice C.M., Vaudin M., Coulson A., Nelson D.L.,
RA Weinstock G., Sulston J.E., Durbin R.M., Hubbard T., Gibbs R.A., Beck S.,
RA Rogers J., Bentley D.R.;
RT "The DNA sequence of the human X chromosome.";
RL Nature 434:325-337(2005).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RA Mural R.J., Istrail S., Sutton G., Florea L., Halpern A.L., Mobarry C.M.,
RA Lippert R., Walenz B., Shatkay H., Dew I., Miller J.R., Flanigan M.J.,
RA Edwards N.J., Bolanos R., Fasulo D., Halldorsson B.V., Hannenhalli S.,
RA Turner R., Yooseph S., Lu F., Nusskern D.R., Shue B.C., Zheng X.H.,
RA Zhong F., Delcher A.L., Huson D.H., Kravitz S.A., Mouchard L., Reinert K.,
RA Remington K.A., Clark A.G., Waterman M.S., Eichler E.E., Adams M.D.,
RA Hunkapiller M.W., Myers E.W., Venter J.C.;
RL Submitted (JUL-2005) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1).
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- INTERACTION:
CC Q8IZU0; Q9ULW3: ABT1; NbExp=3; IntAct=EBI-10175124, EBI-2602396;
CC Q8IZU0; Q8N2N9: ANKRD36B; NbExp=3; IntAct=EBI-10175124, EBI-2876112;
CC Q8IZU0; Q9BXS5: AP1M1; NbExp=3; IntAct=EBI-10175124, EBI-541426;
CC Q8IZU0; Q9NWX5: ASB6; NbExp=3; IntAct=EBI-10175124, EBI-6425205;
CC Q8IZU0; P17544: ATF7; NbExp=3; IntAct=EBI-10175124, EBI-765623;
CC Q8IZU0; Q9NWT8: AURKAIP1; NbExp=3; IntAct=EBI-10175124, EBI-448665;
CC Q8IZU0; P46379: BAG6; NbExp=3; IntAct=EBI-10175124, EBI-347552;
CC Q8IZU0; Q99728: BARD1; NbExp=3; IntAct=EBI-10175124, EBI-473181;
CC Q8IZU0; Q16548: BCL2A1; NbExp=3; IntAct=EBI-10175124, EBI-1003550;
CC Q8IZU0; Q53XK0: BET1; NbExp=3; IntAct=EBI-10175124, EBI-10242927;
CC Q8IZU0; Q6QNY1: BLOC1S2; NbExp=3; IntAct=EBI-10175124, EBI-465872;
CC Q8IZU0; Q0VDD7: BRME1; NbExp=3; IntAct=EBI-10175124, EBI-741210;
CC Q8IZU0; Q13895: BYSL; NbExp=5; IntAct=EBI-10175124, EBI-358049;
CC Q8IZU0; Q14CZ0: C16orf72; NbExp=5; IntAct=EBI-10175124, EBI-10234807;
CC Q8IZU0; Q9H7E9: C8orf33; NbExp=3; IntAct=EBI-10175124, EBI-715389;
CC Q8IZU0; Q9ULU8-4: CADPS; NbExp=3; IntAct=EBI-10175124, EBI-10180690;
CC Q8IZU0; Q9BWC9: CCDC106; NbExp=8; IntAct=EBI-10175124, EBI-711501;
CC Q8IZU0; Q8IYX3: CCDC116; NbExp=3; IntAct=EBI-10175124, EBI-744311;
CC Q8IZU0; Q9NVL8: CCDC198; NbExp=3; IntAct=EBI-10175124, EBI-10238351;
CC Q8IZU0; Q6NSX1: CCDC70; NbExp=3; IntAct=EBI-10175124, EBI-6873045;
CC Q8IZU0; Q9UJX2: CDC23; NbExp=3; IntAct=EBI-10175124, EBI-396137;
CC Q8IZU0; Q16543: CDC37; NbExp=3; IntAct=EBI-10175124, EBI-295634;
CC Q8IZU0; Q9H3Q1: CDC42EP4; NbExp=5; IntAct=EBI-10175124, EBI-744665;
CC Q8IZU0; Q96GN5: CDCA7L; NbExp=3; IntAct=EBI-10175124, EBI-5278764;
CC Q8IZU0; Q8N0S6: CENPL; NbExp=3; IntAct=EBI-10175124, EBI-8467109;
CC Q8IZU0; Q8IYX8-2: CEP57L1; NbExp=3; IntAct=EBI-10175124, EBI-10181988;
CC Q8IZU0; Q96GE4: CEP95; NbExp=4; IntAct=EBI-10175124, EBI-372775;
CC Q8IZU0; Q9NRG0: CHRAC1; NbExp=7; IntAct=EBI-10175124, EBI-2795492;
CC Q8IZU0; P35523: CLCN1; NbExp=3; IntAct=EBI-10175124, EBI-10206780;
CC Q8IZU0; Q9P218-2: COL20A1; NbExp=3; IntAct=EBI-10175124, EBI-10318410;
CC Q8IZU0; O75534: CSDE1; NbExp=3; IntAct=EBI-10175124, EBI-719186;
CC Q8IZU0; Q2TBE0: CWF19L2; NbExp=3; IntAct=EBI-10175124, EBI-5453285;
CC Q8IZU0; Q9UIK4: DAPK2; NbExp=4; IntAct=EBI-10175124, EBI-77154;
CC Q8IZU0; Q9UER7: DAXX; NbExp=4; IntAct=EBI-10175124, EBI-77321;
CC Q8IZU0; Q9H6A0: DENND2D; NbExp=3; IntAct=EBI-10175124, EBI-10307465;
CC Q8IZU0; A0A0S2Z3T7: DGUOK; NbExp=4; IntAct=EBI-10175124, EBI-16436767;
CC Q8IZU0; Q9Y5T4: DNAJC15; NbExp=3; IntAct=EBI-10175124, EBI-10329228;
CC Q8IZU0; Q96FY5: DNAJC4; NbExp=3; IntAct=EBI-10175124, EBI-10286235;
CC Q8IZU0; Q6IB29: EBNA1BP2; NbExp=3; IntAct=EBI-10175124, EBI-10249955;
CC Q8IZU0; Q99848: EBNA1BP2; NbExp=5; IntAct=EBI-10175124, EBI-1048111;
CC Q8IZU0; Q13011: ECH1; NbExp=3; IntAct=EBI-10175124, EBI-711968;
CC Q8IZU0; O75821: EIF3G; NbExp=3; IntAct=EBI-10175124, EBI-366632;
CC Q8IZU0; Q14241: ELOA; NbExp=3; IntAct=EBI-10175124, EBI-742350;
CC Q8IZU0; Q3B820: FAM161A; NbExp=3; IntAct=EBI-10175124, EBI-719941;
CC Q8IZU0; Q8IZU1: FAM9A; NbExp=5; IntAct=EBI-10175124, EBI-8468186;
CC Q8IZU0; Q14CZ7: FASTKD3; NbExp=4; IntAct=EBI-10175124, EBI-10234819;
CC Q8IZU0; O94868: FCHSD2; NbExp=4; IntAct=EBI-10175124, EBI-1215612;
CC Q8IZU0; Q96RJ6: FERD3L; NbExp=4; IntAct=EBI-10175124, EBI-10183007;
CC Q8IZU0; Q9BVV2: FNDC11; NbExp=3; IntAct=EBI-10175124, EBI-744935;
CC Q8IZU0; Q9NXC2: GFOD1; NbExp=4; IntAct=EBI-10175124, EBI-8799578;
CC Q8IZU0; Q9HD26-2: GOPC; NbExp=3; IntAct=EBI-10175124, EBI-11102276;
CC Q8IZU0; Q6IC98: GRAMD4; NbExp=3; IntAct=EBI-10175124, EBI-10962409;
CC Q8IZU0; Q9Y2Q3: GSTK1; NbExp=4; IntAct=EBI-10175124, EBI-1053767;
CC Q8IZU0; P21815: IBSP; NbExp=3; IntAct=EBI-10175124, EBI-18400392;
CC Q8IZU0; Q9H1K1: ISCU; NbExp=3; IntAct=EBI-10175124, EBI-1047335;
CC Q8IZU0; Q86VZ6: JAZF1; NbExp=3; IntAct=EBI-10175124, EBI-11023753;
CC Q8IZU0; P52954: LBX1; NbExp=3; IntAct=EBI-10175124, EBI-20141748;
CC Q8IZU0; O14910: LIN7A; NbExp=3; IntAct=EBI-10175124, EBI-2513988;
CC Q8IZU0; Q8TBB1: LNX1; NbExp=3; IntAct=EBI-10175124, EBI-739832;
CC Q8IZU0; Q9NU23: LYRM2; NbExp=4; IntAct=EBI-10175124, EBI-10313813;
CC Q8IZU0; Q8N8X9: MAB21L3; NbExp=3; IntAct=EBI-10175124, EBI-10268010;
CC Q8IZU0; P55081: MFAP1; NbExp=3; IntAct=EBI-10175124, EBI-1048159;
CC Q8IZU0; Q8NEQ2: MGC24125; NbExp=3; IntAct=EBI-10175124, EBI-10270788;
CC Q8IZU0; Q9H8S9: MOB1A; NbExp=3; IntAct=EBI-10175124, EBI-748229;
CC Q8IZU0; Q9UBU8: MORF4L1; NbExp=3; IntAct=EBI-10175124, EBI-399246;
CC Q8IZU0; Q15014: MORF4L2; NbExp=3; IntAct=EBI-10175124, EBI-399257;
CC Q8IZU0; Q7Z7H8: MRPL10; NbExp=3; IntAct=EBI-10175124, EBI-723524;
CC Q8IZU0; Q13084: MRPL28; NbExp=3; IntAct=EBI-10175124, EBI-723426;
CC Q8IZU0; Q9BYD2: MRPL9; NbExp=3; IntAct=EBI-10175124, EBI-726059;
CC Q8IZU0; Q96E11: MRRF; NbExp=3; IntAct=EBI-10175124, EBI-2855755;
CC Q8IZU0; Q9HB07: MYG1; NbExp=4; IntAct=EBI-10175124, EBI-709754;
CC Q8IZU0; O96000: NDUFB10; NbExp=6; IntAct=EBI-10175124, EBI-1246371;
CC Q8IZU0; O76041: NEBL; NbExp=3; IntAct=EBI-10175124, EBI-2880203;
CC Q8IZU0; O94818-2: NOL4; NbExp=3; IntAct=EBI-10175124, EBI-10190763;
CC Q8IZU0; A8MTQ0: NOTO; NbExp=3; IntAct=EBI-10175124, EBI-17490746;
CC Q8IZU0; O75459: PAGE1; NbExp=3; IntAct=EBI-10175124, EBI-2559100;
CC Q8IZU0; Q5JUK9: PAGE3; NbExp=3; IntAct=EBI-10175124, EBI-10244544;
CC Q8IZU0; O14832: PHYH; NbExp=7; IntAct=EBI-10175124, EBI-721853;
CC Q8IZU0; Q9Y237: PIN4; NbExp=4; IntAct=EBI-10175124, EBI-714599;
CC Q8IZU0; Q9UGP5-2: POLL; NbExp=3; IntAct=EBI-10175124, EBI-10320765;
CC Q8IZU0; Q6NYC8: PPP1R18; NbExp=3; IntAct=EBI-10175124, EBI-2557469;
CC Q8IZU0; O43395: PRPF3; NbExp=9; IntAct=EBI-10175124, EBI-744322;
CC Q8IZU0; O00487: PSMD14; NbExp=3; IntAct=EBI-10175124, EBI-722193;
CC Q8IZU0; Q86Y79: PTRH1; NbExp=3; IntAct=EBI-10175124, EBI-2602515;
CC Q8IZU0; Q9H0T7: RAB17; NbExp=3; IntAct=EBI-10175124, EBI-721615;
CC Q8IZU0; O15315: RAD51B; NbExp=3; IntAct=EBI-10175124, EBI-2824089;
CC Q8IZU0; Q96I25: RBM17; NbExp=3; IntAct=EBI-10175124, EBI-740272;
CC Q8IZU0; Q86U06: RBM23; NbExp=3; IntAct=EBI-10175124, EBI-780319;
CC Q8IZU0; Q9NWS8: RMND1; NbExp=3; IntAct=EBI-10175124, EBI-4401316;
CC Q8IZU0; O76064: RNF8; NbExp=3; IntAct=EBI-10175124, EBI-373337;
CC Q8IZU0; P32969: RPL9P9; NbExp=3; IntAct=EBI-10175124, EBI-358122;
CC Q8IZU0; Q9UHA3: RSL24D1; NbExp=3; IntAct=EBI-10175124, EBI-749321;
CC Q8IZU0; Q92622: RUBCN; NbExp=3; IntAct=EBI-10175124, EBI-2952709;
CC Q8IZU0; Q9BVN2: RUSC1; NbExp=5; IntAct=EBI-10175124, EBI-6257312;
CC Q8IZU0; O00560: SDCBP; NbExp=6; IntAct=EBI-10175124, EBI-727004;
CC Q8IZU0; Q9H190: SDCBP2; NbExp=3; IntAct=EBI-10175124, EBI-742426;
CC Q8IZU0; P07093: SERPINE2; NbExp=3; IntAct=EBI-10175124, EBI-10195168;
CC Q8IZU0; P31947: SFN; NbExp=3; IntAct=EBI-10175124, EBI-476295;
CC Q8IZU0; O15427: SLC16A3; NbExp=3; IntAct=EBI-10175124, EBI-7600166;
CC Q8IZU0; P03973: SLPI; NbExp=6; IntAct=EBI-10175124, EBI-355293;
CC Q8IZU0; Q12824-2: SMARCB1; NbExp=3; IntAct=EBI-10175124, EBI-358436;
CC Q8IZU0; Q16637: SMN2; NbExp=8; IntAct=EBI-10175124, EBI-395421;
CC Q8IZU0; O95721: SNAP29; NbExp=3; IntAct=EBI-10175124, EBI-490676;
CC Q8IZU0; Q5SQN1: SNAP47; NbExp=3; IntAct=EBI-10175124, EBI-10244848;
CC Q8IZU0; Q7Z614: SNX20; NbExp=4; IntAct=EBI-10175124, EBI-744896;
CC Q8IZU0; A7MD48: SRRM4; NbExp=3; IntAct=EBI-10175124, EBI-3867173;
CC Q8IZU0; Q13188: STK3; NbExp=3; IntAct=EBI-10175124, EBI-992580;
CC Q8IZU0; E5KS60: SUCLA2; NbExp=3; IntAct=EBI-10175124, EBI-10176959;
CC Q8IZU0; O75683: SURF6; NbExp=3; IntAct=EBI-10175124, EBI-2691252;
CC Q8IZU0; Q9BSW7: SYT17; NbExp=4; IntAct=EBI-10175124, EBI-745392;
CC Q8IZU0; Q3MII6: TBC1D25; NbExp=3; IntAct=EBI-10175124, EBI-11899977;
CC Q8IZU0; Q969Z0: TBRG4; NbExp=3; IntAct=EBI-10175124, EBI-702328;
CC Q8IZU0; Q15560: TCEA2; NbExp=3; IntAct=EBI-10175124, EBI-710310;
CC Q8IZU0; Q8N8B7: TCEANC; NbExp=3; IntAct=EBI-10175124, EBI-954696;
CC Q8IZU0; Q15582: TGFBI; NbExp=3; IntAct=EBI-10175124, EBI-10236573;
CC Q8IZU0; Q6ZVM7-2: TOM1L2; NbExp=5; IntAct=EBI-10175124, EBI-12147805;
CC Q8IZU0; Q9BVS5: TRMT61B; NbExp=4; IntAct=EBI-10175124, EBI-3197877;
CC Q8IZU0; Q99816: TSG101; NbExp=3; IntAct=EBI-10175124, EBI-346882;
CC Q8IZU0; A0A384ME17: TUFM; NbExp=3; IntAct=EBI-10175124, EBI-12261790;
CC Q8IZU0; P49411: TUFM; NbExp=4; IntAct=EBI-10175124, EBI-359097;
CC Q8IZU0; Q99757: TXN2; NbExp=3; IntAct=EBI-10175124, EBI-2932492;
CC Q8IZU0; Q96LR5: UBE2E2; NbExp=3; IntAct=EBI-10175124, EBI-2129763;
CC Q8IZU0; Q96HZ7: URB1-AS1; NbExp=3; IntAct=EBI-10175124, EBI-10288943;
CC Q8IZU0; Q13426: XRCC4; NbExp=7; IntAct=EBI-10175124, EBI-717592;
CC Q8IZU0; Q9Y2Z4: YARS2; NbExp=3; IntAct=EBI-10175124, EBI-1049286;
CC Q8IZU0; Q8TBK6: ZCCHC10; NbExp=3; IntAct=EBI-10175124, EBI-597063;
CC Q8IZU0; Q8N5A5: ZGPAT; NbExp=3; IntAct=EBI-10175124, EBI-3439227;
CC Q8IZU0; Q8N5A5-2: ZGPAT; NbExp=3; IntAct=EBI-10175124, EBI-10183064;
CC Q8IZU0; P51814: ZNF41; NbExp=3; IntAct=EBI-10175124, EBI-2681830;
CC Q8IZU0; P51814-6: ZNF41; NbExp=6; IntAct=EBI-10175124, EBI-12700258;
CC Q8IZU0; Q86VK4: ZNF410; NbExp=3; IntAct=EBI-10175124, EBI-720304;
CC Q8IZU0; Q8N184: ZNF567; NbExp=3; IntAct=EBI-10175124, EBI-749400;
CC Q8IZU0; Q8N883: ZNF614; NbExp=3; IntAct=EBI-10175124, EBI-9675993;
CC Q8IZU0; Q9ULD5: ZNF777; NbExp=3; IntAct=EBI-10175124, EBI-11975599;
CC Q8IZU0; A0A1U9X8X8; NbExp=3; IntAct=EBI-10175124, EBI-17234977;
CC Q8IZU0; Q9H614; NbExp=3; IntAct=EBI-10175124, EBI-10249899;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000269|PubMed:12213195}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=Q8IZU0-1; Sequence=Displayed;
CC Name=2;
CC IsoId=Q8IZU0-2; Sequence=VSP_055087, VSP_055088;
CC -!- TISSUE SPECIFICITY: Expressed exclusively in testis.
CC {ECO:0000269|PubMed:12213195}.
CC -!- SIMILARITY: Belongs to the FAM9 family. {ECO:0000305}.
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DR EMBL; AF494344; AAN07163.1; -; mRNA.
DR EMBL; AK097501; BAC05078.1; -; mRNA.
DR EMBL; AC074281; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC119567; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AC119618; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH471074; EAW98763.1; -; Genomic_DNA.
DR EMBL; BC120955; AAI20956.1; -; mRNA.
DR EMBL; BC120956; AAI20957.1; -; mRNA.
DR CCDS; CCDS14132.1; -. [Q8IZU0-1]
DR RefSeq; NP_995321.1; NM_205849.3. [Q8IZU0-1]
DR RefSeq; XP_011543766.1; XM_011545464.2.
DR AlphaFoldDB; Q8IZU0; -.
DR SMR; Q8IZU0; -.
DR BioGRID; 128131; 167.
DR IntAct; Q8IZU0; 138.
DR STRING; 9606.ENSP00000318716; -.
DR MoonDB; Q8IZU0; Predicted.
DR BioMuta; FAM9B; -.
DR DMDM; 29336758; -.
DR jPOST; Q8IZU0; -.
DR MassIVE; Q8IZU0; -.
DR PaxDb; Q8IZU0; -.
DR PeptideAtlas; Q8IZU0; -.
DR PRIDE; Q8IZU0; -.
DR Antibodypedia; 23614; 29 antibodies from 13 providers.
DR DNASU; 171483; -.
DR Ensembl; ENST00000327220.10; ENSP00000318716.5; ENSG00000177138.17. [Q8IZU0-1]
DR Ensembl; ENST00000362066.7; ENSP00000354770.3; ENSG00000177138.17. [Q8IZU0-2]
DR Ensembl; ENST00000428477.1; ENSP00000412606.1; ENSG00000177138.17. [Q8IZU0-1]
DR Ensembl; ENST00000472522.6; ENSP00000431456.2; ENSG00000177138.17. [Q8IZU0-1]
DR Ensembl; ENST00000651278.1; ENSP00000498495.1; ENSG00000177138.17. [Q8IZU0-1]
DR GeneID; 171483; -.
DR KEGG; hsa:171483; -.
DR MANE-Select; ENST00000327220.10; ENSP00000318716.5; NM_205849.3; NP_995321.1.
DR UCSC; uc004csh.4; human. [Q8IZU0-1]
DR CTD; 171483; -.
DR GeneCards; FAM9B; -.
DR HGNC; HGNC:18404; FAM9B.
DR HPA; ENSG00000177138; Tissue enhanced (liver, testis).
DR MIM; 300478; gene.
DR neXtProt; NX_Q8IZU0; -.
DR OpenTargets; ENSG00000177138; -.
DR PharmGKB; PA27993; -.
DR VEuPathDB; HostDB:ENSG00000177138; -.
DR eggNOG; ENOG502TD36; Eukaryota.
DR GeneTree; ENSGT00390000000062; -.
DR HOGENOM; CLU_083208_0_0_1; -.
DR InParanoid; Q8IZU0; -.
DR OMA; MDKACSK; -.
DR OrthoDB; 1187915at2759; -.
DR PhylomeDB; Q8IZU0; -.
DR TreeFam; TF328876; -.
DR PathwayCommons; Q8IZU0; -.
DR SignaLink; Q8IZU0; -.
DR BioGRID-ORCS; 171483; 13 hits in 684 CRISPR screens.
DR ChiTaRS; FAM9B; human.
DR GenomeRNAi; 171483; -.
DR Pharos; Q8IZU0; Tdark.
DR PRO; PR:Q8IZU0; -.
DR Proteomes; UP000005640; Chromosome X.
DR RNAct; Q8IZU0; protein.
DR Bgee; ENSG00000177138; Expressed in right lobe of liver and 64 other tissues.
DR ExpressionAtlas; Q8IZU0; baseline and differential.
DR Genevisible; Q8IZU0; HS.
DR GO; GO:0005654; C:nucleoplasm; IDA:HPA.
DR GO; GO:0000795; C:synaptonemal complex; IBA:GO_Central.
DR GO; GO:0051321; P:meiotic cell cycle; IBA:GO_Central.
DR GO; GO:0007286; P:spermatid development; IBA:GO_Central.
DR InterPro; IPR006888; XLR/SYCP3/FAM9_dom.
DR Pfam; PF04803; Cor1; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Nucleus; Reference proteome.
FT CHAIN 1..186
FT /note="Protein FAM9B"
FT /id="PRO_0000119033"
FT REGION 1..93
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 8..80
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT VAR_SEQ 1
FT /note="M -> MPGFLSFLSVSLRSPGSGIASSFPGQPATDPVGRRAAKAQLEAQFM
FT (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:14702039"
FT /id="VSP_055087"
FT VAR_SEQ 61..93
FT /note="EDLTAKRKRMKMDKTCSKTKNKSKHALRKKQLK -> VGANNFKNYPVHIGV
FT SSEQHILLDCSLS (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:14702039"
FT /id="VSP_055088"
SQ SEQUENCE 186 AA; 22438 MW; 234509A205433927 CRC64;
MAAWGKKHAG KDPVRDECEE RNRFTETREE DVTDEHGERE PFAETDEHTG ANTKKPEDTA
EDLTAKRKRM KMDKTCSKTK NKSKHALRKK QLKRQKRDYI HSLKLLNVLE EYITDEQKEE
EEEEGEEEEL IRIFQEQQKK WQQYRSVRRE RLKEMKLLRD QFVKALEDFE DLCDRVFSDE
DSELDN