ID   FAPR_GEOKA              Reviewed;         198 AA.
AC   Q5L0Q8;
DT   20-DEC-2005, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-2005, sequence version 1.
DT   25-MAY-2022, entry version 95.
DE   RecName: Full=Transcription factor FapR {ECO:0000255|HAMAP-Rule:MF_01814};
DE   AltName: Full=Fatty acid and phospholipid biosynthesis regulator {ECO:0000255|HAMAP-Rule:MF_01814};
GN   Name=fapR {ECO:0000255|HAMAP-Rule:MF_01814}; OrderedLocusNames=GK1187;
OS   Geobacillus kaustophilus (strain HTA426).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Geobacillus;
OC   Geobacillus thermoleovorans group.
OX   NCBI_TaxID=235909;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HTA426;
RX   PubMed=15576355; DOI=10.1093/nar/gkh970;
RA   Takami H., Takaki Y., Chee G.-J., Nishi S., Shimamura S., Suzuki H.,
RA   Matsui S., Uchiyama I.;
RT   "Thermoadaptation trait revealed by the genome sequence of thermophilic
RT   Geobacillus kaustophilus.";
RL   Nucleic Acids Res. 32:6292-6303(2004).
CC   -!- FUNCTION: Transcriptional factor involved in regulation of membrane
CC       lipid biosynthesis by repressing genes involved in fatty acid and
CC       phospholipid metabolism. {ECO:0000255|HAMAP-Rule:MF_01814}.
CC   -!- SIMILARITY: Belongs to the FapR family. {ECO:0000255|HAMAP-
CC       Rule:MF_01814}.
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DR   EMBL; BA000043; BAD75472.1; -; Genomic_DNA.
DR   RefSeq; WP_011230687.1; NC_006510.1.
DR   AlphaFoldDB; Q5L0Q8; -.
DR   SMR; Q5L0Q8; -.
DR   STRING; 235909.GK1187; -.
DR   EnsemblBacteria; BAD75472; BAD75472; GK1187.
DR   KEGG; gka:GK1187; -.
DR   eggNOG; COG1349; Bacteria.
DR   eggNOG; COG2050; Bacteria.
DR   HOGENOM; CLU_095708_0_0_9; -.
DR   OMA; GIARGHH; -.
DR   Proteomes; UP000001172; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0045717; P:negative regulation of fatty acid biosynthetic process; IEA:UniProtKB-UniRule.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IEA:UniProtKB-UniRule.
DR   Gene3D; 1.10.10.10; -; 1.
DR   HAMAP; MF_01814; Transcrip_fact_FapR; 1.
DR   InterPro; IPR029069; HotDog_dom_sf.
DR   InterPro; IPR017275; Transcription_factor_FapR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PIRSF; PIRSF037733; Transcription_factor_FapR; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF54637; SSF54637; 1.
PE   3: Inferred from homology;
KW   DNA-binding; Fatty acid biosynthesis; Fatty acid metabolism;
KW   Lipid biosynthesis; Lipid metabolism; Reference proteome; Repressor;
KW   Transcription; Transcription regulation.
FT   CHAIN           1..198
FT                   /note="Transcription factor FapR"
FT                   /id="PRO_0000172822"
FT   DOMAIN          102..167
FT                   /note="MaoC-like"
SQ   SEQUENCE   198 AA;  22645 MW;  10BAFDA997B7D70F CRC64;
     MRKSKRERQR LLQETIRENP FITDEELAEK FSVSVQTIRL DRLELSIPEL RERIKNVARQ
     SFADKVRALP LEEVIGDIID IEPDASAISI FDVKEEHVFR RTRIARGHHL FAQANSLAVA
     VIHDELALTA KATIRFVRQV KEGERVVAKA KVTGKTAHGR TIVEVNSYVG QELVFSGTFE
     MYRSNIEKKD GDSNEYRG