FAR1_PROCL
ID FAR1_PROCL Reviewed; 7 AA.
AC P38499;
DT 01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-1994, sequence version 1.
DT 11-DEC-2019, entry version 40.
DE RecName: Full=Cardio-excitatory FMRFamide homolog NF1;
OS Procambarus clarkii (Red swamp crayfish).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC Malacostraca; Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;
OC Astacoidea; Cambaridae; Procambarus.
OX NCBI_TaxID=6728;
RN [1]
RP PROTEIN SEQUENCE, AND AMIDATION AT PHE-7.
RC TISSUE=Pericardial organs;
RX PubMed=8387183; DOI=10.1016/0196-9781(93)90021-8;
RA Mercier A.J., Orchard I., Tebrugge V., Skerrett M.;
RT "Isolation of two FMRFamide-related peptides from crayfish pericardial
RT organs.";
RL Peptides 14:137-143(1993).
CC -!- FUNCTION: Increases the rate and amplitude of spontaneous contractions
CC of semi-isolated hearts. Increases the amplitude of excitatory
CC postsynaptic potentials in abdominal extensor muscle.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- SIMILARITY: Belongs to the FARP (FMRFamide related peptide) family.
CC {ECO:0000305}.
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DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Neuropeptide; Secreted.
FT PEPTIDE 1..7
FT /note="Cardio-excitatory FMRFamide homolog NF1"
FT /id="PRO_0000043704"
FT MOD_RES 7
FT /note="Phenylalanine amide"
FT /evidence="ECO:0000269|PubMed:8387183"
SQ SEQUENCE 7 AA; 966 MW; 69D40729C4540420 CRC64;
NRNFLRF