FAR2_CAEEL
ID FAR2_CAEEL Reviewed; 182 AA.
AC P34383;
DT 01-FEB-1994, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1994, sequence version 1.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Fatty-acid and retinol-binding protein 2;
DE Flags: Precursor;
GN Name=far-2; ORFNames=F02A9.3;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=7906398; DOI=10.1038/368032a0;
RA Wilson R., Ainscough R., Anderson K., Baynes C., Berks M., Bonfield J.,
RA Burton J., Connell M., Copsey T., Cooper J., Coulson A., Craxton M.,
RA Dear S., Du Z., Durbin R., Favello A., Fraser A., Fulton L., Gardner A.,
RA Green P., Hawkins T., Hillier L., Jier M., Johnston L., Jones M.,
RA Kershaw J., Kirsten J., Laisster N., Latreille P., Lightning J., Lloyd C.,
RA Mortimore B., O'Callaghan M., Parsons J., Percy C., Rifken L., Roopra A.,
RA Saunders D., Shownkeen R., Sims M., Smaldon N., Smith A., Smith M.,
RA Sonnhammer E., Staden R., Sulston J., Thierry-Mieg J., Thomas K.,
RA Vaudin M., Vaughan K., Waterston R., Watson A., Weinstock L.,
RA Wilkinson-Sproat J., Wohldman P.;
RT "2.2 Mb of contiguous nucleotide sequence from chromosome III of C.
RT elegans.";
RL Nature 368:32-38(1994).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Probably binds lipids. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the fatty-acid and retinol-binding protein
CC (FARBP) family. {ECO:0000305}.
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DR EMBL; Z19555; CAA79617.1; -; Genomic_DNA.
DR PIR; S28311; S28311.
DR RefSeq; NP_499011.1; NM_066610.4.
DR AlphaFoldDB; P34383; -.
DR SMR; P34383; -.
DR BioGRID; 41483; 21.
DR DIP; DIP-24469N; -.
DR IntAct; P34383; 2.
DR MINT; P34383; -.
DR STRING; 6239.F02A9.3.3; -.
DR World-2DPAGE; 0011:P34383; -.
DR EPD; P34383; -.
DR PaxDb; P34383; -.
DR PeptideAtlas; P34383; -.
DR EnsemblMetazoa; F02A9.3.1; F02A9.3.1; WBGene00001386.
DR GeneID; 176284; -.
DR KEGG; cel:CELE_F02A9.3; -.
DR UCSC; F02A9.3.1; c. elegans.
DR CTD; 176284; -.
DR WormBase; F02A9.3; CE00134; WBGene00001386; far-2.
DR eggNOG; ENOG502R1CS; Eukaryota.
DR GeneTree; ENSGT00970000195891; -.
DR HOGENOM; CLU_117803_0_0_1; -.
DR InParanoid; P34383; -.
DR OMA; EMYDITR; -.
DR OrthoDB; 1383457at2759; -.
DR PhylomeDB; P34383; -.
DR PRO; PR:P34383; -.
DR Proteomes; UP000001940; Chromosome III.
DR Bgee; WBGene00001386; Expressed in adult organism and 4 other tissues.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0005504; F:fatty acid binding; ISS:WormBase.
DR GO; GO:0019841; F:retinol binding; ISS:WormBase.
DR InterPro; IPR008632; Gp-FAR-1.
DR PANTHER; PTHR31418; PTHR31418; 1.
DR Pfam; PF05823; Gp-FAR-1; 1.
PE 3: Inferred from homology;
KW Coiled coil; Lipid-binding; Reference proteome; Secreted; Signal.
FT SIGNAL 1..17
FT /evidence="ECO:0000255"
FT CHAIN 18..182
FT /note="Fatty-acid and retinol-binding protein 2"
FT /id="PRO_0000008768"
FT COILED 46..73
FT /evidence="ECO:0000255"
FT COILED 131..152
FT /evidence="ECO:0000255"
SQ SEQUENCE 182 AA; 20035 MW; B20FD0AFACC13BBA CRC64;
MIRAFLVVAL ASVAVFSAPI PEVPQNFDDI PAEYKGLIPA EVAEHLKAIT AEEKAALKEL
AQNHKEYKTE EEFKAALKEK SPSLYEKAGK LEALLTAKFE KLDATAQALV KKIIAKGREL
HQQYLAGDKP TLDSLKELAK GYIAEYKALS DDAKATITAE FPILTGFFQN EKIQAIVGQY
VN
