ID   FAR2_KARBO              Reviewed;           8 AA.
AC   B0M8U1;
DT   06-MAR-2013, integrated into UniProtKB/Swiss-Prot.
DT   06-MAR-2013, sequence version 1.
DT   11-DEC-2019, entry version 7.
DE   RecName: Full=Extended FMRFamide-2 {ECO:0000303|PubMed:22508719};
DE            Short=FMRFa-2 {ECO:0000303|PubMed:22508719};
OS   Karoophasma botterkloofense (Gladiator) (Heel-walker).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Polyneoptera; Mantophasmatodea; Austrophasmatidae; Karoophasma.
OX   NCBI_TaxID=253132;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, AND AMIDATION AT ARG-8.
RC   TISSUE=Thoracic perisympathetic organs {ECO:0000269|PubMed:22508719};
RX   PubMed=22508719; DOI=10.1093/sysbio/sys003;
RA   Predel R., Neupert S., Huetteroth W., Kahnt J., Waidelich D., Roth S.;
RT   "Peptidomics-based phylogeny and biogeography of Mantophasmatodea
RT   (Hexapoda).";
RL   Syst. Biol. 61:609-629(2012).
CC   -!- FUNCTION: FMRFamides and FMRFamide-like peptides are neuropeptides.
CC       {ECO:0000250|UniProtKB:P34405}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:22508719}.
CC   -!- SIMILARITY: Belongs to the FARP (FMRF amide related peptide) family.
CC       {ECO:0000255}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Neuropeptide; Secreted.
FT   PEPTIDE         1..8
FT                   /note="Extended FMRFamide-2"
FT                   /evidence="ECO:0000269|PubMed:22508719"
FT                   /id="PRO_0000421488"
FT   MOD_RES         8
FT                   /note="Arginine amide"
FT                   /evidence="ECO:0000269|PubMed:22508719"
FT   UNSURE          4
FT                   /note="L or I"
FT                   /evidence="ECO:0000269|PubMed:22508719"
FT   UNSURE          6
FT                   /note="L or I"
FT                   /evidence="ECO:0000269|PubMed:22508719"
SQ   SEQUENCE   8 AA;  965 MW;  DB0DD736D73B5AB5 CRC64;
     SDYLQLAR