ID   FAR2_PROCL              Reviewed;           7 AA.
AC   P38498;
DT   01-OCT-1994, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1994, sequence version 1.
DT   11-DEC-2019, entry version 40.
DE   RecName: Full=Cardio-excitatory FMRFamide homolog DF2;
OS   Procambarus clarkii (Red swamp crayfish).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Crustacea; Multicrustacea;
OC   Malacostraca; Eumalacostraca; Eucarida; Decapoda; Pleocyemata; Astacidea;
OC   Astacoidea; Cambaridae; Procambarus.
OX   NCBI_TaxID=6728;
RN   [1]
RP   PROTEIN SEQUENCE, AND AMIDATION AT PHE-7.
RC   TISSUE=Pericardial organs;
RX   PubMed=8387183; DOI=10.1016/0196-9781(93)90021-8;
RA   Mercier A.J., Orchard I., Tebrugge V., Skerrett M.;
RT   "Isolation of two FMRFamide-related peptides from crayfish pericardial
RT   organs.";
RL   Peptides 14:137-143(1993).
CC   -!- FUNCTION: Increases the rate and amplitude of spontaneous contractions
CC       of semi-isolated hearts. Increases the amplitude of excitatory
CC       postsynaptic potentials in abdominal extensor muscle.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the FARP (FMRFamide related peptide) family.
CC       {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Neuropeptide; Secreted.
FT   PEPTIDE         1..7
FT                   /note="Cardio-excitatory FMRFamide homolog DF2"
FT                   /id="PRO_0000043705"
FT   MOD_RES         7
FT                   /note="Phenylalanine amide"
FT                   /evidence="ECO:0000269|PubMed:8387183"
SQ   SEQUENCE   7 AA;  967 MW;  69D40729C4540AC0 CRC64;
     DRNFLRF