ID   3MGH_FRATO              Reviewed;         193 AA.
AC   Q0BM56;
DT   12-DEC-2006, integrated into UniProtKB/Swiss-Prot.
DT   17-OCT-2006, sequence version 1.
DT   03-AUG-2022, entry version 70.
DE   RecName: Full=Putative 3-methyladenine DNA glycosylase {ECO:0000255|HAMAP-Rule:MF_00527};
DE            EC=3.2.2.- {ECO:0000255|HAMAP-Rule:MF_00527};
GN   OrderedLocusNames=FTH_0919;
OS   Francisella tularensis subsp. holarctica (strain OSU18).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Thiotrichales;
OC   Francisellaceae; Francisella.
OX   NCBI_TaxID=393011;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=OSU18;
RX   PubMed=16980500; DOI=10.1128/jb.00506-06;
RA   Petrosino J.F., Xiang Q., Karpathy S.E., Jiang H., Yerrapragada S., Liu Y.,
RA   Gioia J., Hemphill L., Gonzalez A., Raghavan T.M., Uzman A., Fox G.E.,
RA   Highlander S., Reichard M., Morton R.J., Clinkenbeard K.D., Weinstock G.M.;
RT   "Chromosome rearrangement and diversification of Francisella tularensis
RT   revealed by the type B (OSU18) genome sequence.";
RL   J. Bacteriol. 188:6977-6985(2006).
CC   -!- SIMILARITY: Belongs to the DNA glycosylase MPG family.
CC       {ECO:0000255|HAMAP-Rule:MF_00527}.
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DR   EMBL; CP000437; ABI82828.1; -; Genomic_DNA.
DR   RefSeq; WP_003018833.1; NC_017463.1.
DR   AlphaFoldDB; Q0BM56; -.
DR   SMR; Q0BM56; -.
DR   GeneID; 60805902; -.
DR   KEGG; fth:FTH_0919; -.
DR   OMA; VEAYHHT; -.
DR   GO; GO:0003905; F:alkylbase DNA N-glycosylase activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0006284; P:base-excision repair; IEA:InterPro.
DR   CDD; cd00540; AAG; 1.
DR   Gene3D; 3.10.300.10; -; 1.
DR   HAMAP; MF_00527; 3MGH; 1.
DR   InterPro; IPR011034; Formyl_transferase-like_C_sf.
DR   InterPro; IPR003180; MPG.
DR   InterPro; IPR036995; MPG_sf.
DR   PANTHER; PTHR10429; PTHR10429; 1.
DR   Pfam; PF02245; Pur_DNA_glyco; 1.
DR   SUPFAM; SSF50486; SSF50486; 1.
DR   TIGRFAMs; TIGR00567; 3mg; 1.
PE   3: Inferred from homology;
KW   DNA damage; DNA repair; Hydrolase.
FT   CHAIN           1..193
FT                   /note="Putative 3-methyladenine DNA glycosylase"
FT                   /id="PRO_0000265021"
SQ   SEQUENCE   193 AA;  21894 MW;  B669A55BB9A301B7 CRC64;
     MNNLEAILRL KTIDAAKKLL GHFLVSKYNN KILIGKIVET EAYLYNDPAC HSYSNRTKRN
     SMMYAQAGTS YVYFTYGMHY CFNVVTADVG IGEAILIRAL EPIAGIEQMQ LNRSKTKLID
     LCSGPAKLTQ ALNINLKDNG INLLDKDSSI LLRYNNDLIN EIDIVQTQRI GISKAKDMPY
     RFYIKDNIFV SKK