ID   FAR6_DELRA              Reviewed;           9 AA.
AC   B3EWK2;
DT   03-OCT-2012, integrated into UniProtKB/Swiss-Prot.
DT   03-OCT-2012, sequence version 1.
DT   02-JUN-2021, entry version 9.
DE   RecName: Full=FMRFamide-like neuropeptide APGQDFMRF-amide {ECO:0000303|PubMed:20869420, ECO:0000303|PubMed:22848525};
OS   Delia radicum (Cabbage root fly) (Anthomyia brassicae).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Muscoidea;
OC   Anthomyiidae; Anthomyiinae; Delia.
OX   NCBI_TaxID=30064;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, TISSUE SPECIFICITY, MASS SPECTROMETRY, AND AMIDATION AT
RP   PHE-9.
RC   TISSUE=Abdominal ganglion {ECO:0000269|PubMed:20869420},
RC   Brain {ECO:0000269|PubMed:20869420},
RC   Corpora allata {ECO:0000269|PubMed:20869420}, and
RC   Corpora cardiaca {ECO:0000269|PubMed:20869420};
RX   PubMed=20869420; DOI=10.1016/j.peptides.2010.08.028;
RA   Audsley N., Matthews H.J., Down R.E., Weaver R.J.;
RT   "Neuropeptides associated with the central nervous system of the cabbage
RT   root fly, Delia radicum (L).";
RL   Peptides 32:434-440(2011).
RN   [2] {ECO:0000305}
RP   PROTEIN SEQUENCE, TISSUE SPECIFICITY, DEVELOPMENTAL STAGE, MASS
RP   SPECTROMETRY, AND AMIDATION AT PHE-9.
RC   TISSUE=CNS {ECO:0000269|PubMed:22848525};
RX   PubMed=22848525; DOI=10.1371/journal.pone.0041543;
RA   Zoephel J., Reiher W., Rexer K.-H., Kahnt J., Wegener C.;
RT   "Peptidomics of the agriculturally damaging larval stage of the cabbage
RT   root fly Delia radicum (Diptera: Anthomyiidae).";
RL   PLoS ONE 7:E41543-E41543(2012).
CC   -!- FUNCTION: FMRFamides and FMRFamide-like peptides are neuropeptides.
CC       {ECO:0000250|UniProtKB:P41855}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250|UniProtKB:P41860}.
CC   -!- TISSUE SPECIFICITY: In larvae, expressed in the CNS and thoracic
CC       perisymapthetic organs (tPSO) but not in the ring gland or abdominal
CC       perisymapthetic organs (aPSO) (at protein level). In adults, expressed
CC       in brain and thoracic-abdominal ganglion but not in corpora cardiaca
CC       and corpora allata (at protein level). {ECO:0000269|PubMed:20869420,
CC       ECO:0000269|PubMed:22848525}.
CC   -!- DEVELOPMENTAL STAGE: Detected in larvae and adults.
CC       {ECO:0000269|PubMed:20869420, ECO:0000269|PubMed:22848525}.
CC   -!- MASS SPECTROMETRY: Mass=1067.5; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:20869420, ECO:0000269|PubMed:22848525};
CC   -!- MASS SPECTROMETRY: Mass=1067.51; Method=MALDI;
CC       Evidence={ECO:0000269|PubMed:20869420, ECO:0000269|PubMed:22848525};
CC   -!- SIMILARITY: Belongs to the FARP (FMRFamide related peptide) family.
CC       {ECO:0000255}.
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DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Amidation; Direct protein sequencing; Neuropeptide; Secreted.
FT   PEPTIDE         1..9
FT                   /note="FMRFamide-like neuropeptide APGQDFMRF-amide"
FT                   /evidence="ECO:0000269|PubMed:20869420,
FT                   ECO:0000269|PubMed:22848525"
FT                   /id="PRO_0000419706"
FT   MOD_RES         9
FT                   /note="Phenylalanine amide"
FT                   /evidence="ECO:0000269|PubMed:20869420,
FT                   ECO:0000269|PubMed:22848525"
SQ   SEQUENCE   9 AA;  1068 MW;  39D10699CAB6D867 CRC64;
     APGQDFMRF