FARP_MANSE
ID FARP_MANSE Reviewed; 10 AA.
AC P18523;
DT 01-NOV-1990, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1994, sequence version 2.
DT 02-JUN-2021, entry version 53.
DE RecName: Full=FMRFamide-like neuropeptide;
OS Manduca sexta (Tobacco hawkmoth) (Tobacco hornworm).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Bombycoidea;
OC Sphingidae; Sphinginae; Sphingini; Manduca.
OX NCBI_TaxID=7130;
RN [1]
RP PROTEIN SEQUENCE, PYROGLUTAMATE FORMATION AT GLN-1, AND AMIDATION AT
RP PHE-10.
RX PubMed=2235684; DOI=10.1016/0196-9781(90)90203-h;
RA Kingan T.G., Teplow D.B., Phillips J.M., Riehm J.P., Rao K.R.,
RA Hildebrand J.G., Homberg U., Kammer A.E., Jardine I., Griffin P.R.,
RA Hunt D.F.;
RT "A new peptide in the FMRFamide family isolated from the CNS of the
RT hawkmoth, Manduca sexta.";
RL Peptides 11:849-856(1990).
CC -!- FUNCTION: Increases the force of neurally evoked contractions in the
CC major power-producing flight muscles, the dorsal longitudinal muscles
CC and so is likely to play a role in sustaining or promoting flight
CC behavior patterns.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- SIMILARITY: Belongs to the FARP (FMRFamide related peptide) family.
CC {ECO:0000305}.
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DR PIR; A43977; A43977.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Neuropeptide;
KW Pyrrolidone carboxylic acid; Secreted.
FT PEPTIDE 1..10
FT /note="FMRFamide-like neuropeptide"
FT /id="PRO_0000043692"
FT MOD_RES 1
FT /note="Pyrrolidone carboxylic acid"
FT /evidence="ECO:0000269|PubMed:2235684"
FT MOD_RES 10
FT /note="Phenylalanine amide"
FT /evidence="ECO:0000269|PubMed:2235684"
SQ SEQUENCE 10 AA; 1247 MW; D3C45229D5B1F2D2 CRC64;
QDVVHSFLRF