FARP_SCHGR
ID FARP_SCHGR Reviewed; 10 AA.
AC P84307; P38553;
DT 07-DEC-2004, integrated into UniProtKB/Swiss-Prot.
DT 07-DEC-2004, sequence version 1.
DT 11-DEC-2019, entry version 25.
DE RecName: Full=SchistoFLRFamide;
DE AltName: Full=Cardioexcitatory neuropeptide;
DE AltName: Full=PDVDHFLRF-amide;
OS Schistocerca gregaria (Desert locust) (Gryllus gregarius).
OC Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC Neoptera; Polyneoptera; Orthoptera; Caelifera; Acrididea; Acridomorpha;
OC Acridoidea; Acrididae; Cyrtacanthacridinae; Schistocerca.
OX NCBI_TaxID=7010;
RN [1]
RP PROTEIN SEQUENCE, AMIDATION AT PHE-10, AND FUNCTION.
RC TISSUE=Thoracic nervous system;
RX PubMed=2719702; DOI=10.1016/0006-291x(89)92512-6;
RA Robb S., Packman L.C., Evans P.D.;
RT "Isolation, primary structure and bioactivity of schistoflrf-amide, a FMRF-
RT amide-like neuropeptide from the locust, Schistocerca gregaria.";
RL Biochem. Biophys. Res. Commun. 160:850-856(1989).
CC -!- FUNCTION: Muscle inhibiting agent. Involved in the neural control of
CC the visceral muscles of the heart, accessory glands and oviduct. May be
CC involved in the regulation of saliva secretion.
CC {ECO:0000269|PubMed:2719702}.
CC -!- SUBCELLULAR LOCATION: Secreted.
CC -!- SIMILARITY: Belongs to the FARP (FMRFamide related peptide) family.
CC {ECO:0000305}.
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DR PIR; A32543; A32543.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
PE 1: Evidence at protein level;
KW Amidation; Direct protein sequencing; Neuropeptide; Secreted.
FT PEPTIDE 1..10
FT /note="SchistoFLRFamide"
FT /id="PRO_0000043683"
FT MOD_RES 10
FT /note="Phenylalanine amide"
FT /evidence="ECO:0000269|PubMed:2719702"
SQ SEQUENCE 10 AA; 1244 MW; D3C51729D2C1EAB2 CRC64;
PDVDHVFLRF