ID   AIM32_YEAST             Reviewed;         311 AA.
AC   Q04689; D6VZC5;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1997, sequence version 1.
DT   03-AUG-2022, entry version 121.
DE   RecName: Full=Altered inheritance of mitochondria protein 32;
GN   Name=AIM32; OrderedLocusNames=YML050W; ORFNames=YM9827.02;
OS   Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX   NCBI_TaxID=559292;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=9169872;
RA   Bowman S., Churcher C.M., Badcock K., Brown D., Chillingworth T.,
RA   Connor R., Dedman K., Devlin K., Gentles S., Hamlin N., Hunt S., Jagels K.,
RA   Lye G., Moule S., Odell C., Pearson D., Rajandream M.A., Rice P.,
RA   Skelton J., Walsh S.V., Whitehead S., Barrell B.G.;
RT   "The nucleotide sequence of Saccharomyces cerevisiae chromosome XIII.";
RL   Nature 387:90-93(1997).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=24374639; DOI=10.1534/g3.113.008995;
RA   Engel S.R., Dietrich F.S., Fisk D.G., Binkley G., Balakrishnan R.,
RA   Costanzo M.C., Dwight S.S., Hitz B.C., Karra K., Nash R.S., Weng S.,
RA   Wong E.D., Lloyd P., Skrzypek M.S., Miyasato S.R., Simison M., Cherry J.M.;
RT   "The reference genome sequence of Saccharomyces cerevisiae: Then and now.";
RL   G3 (Bethesda) 4:389-398(2014).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 204508 / S288c;
RX   PubMed=17322287; DOI=10.1101/gr.6037607;
RA   Hu Y., Rolfs A., Bhullar B., Murthy T.V.S., Zhu C., Berger M.F.,
RA   Camargo A.A., Kelley F., McCarron S., Jepson D., Richardson A., Raphael J.,
RA   Moreira D., Taycher E., Zuo D., Mohr S., Kane M.F., Williamson J.,
RA   Simpson A.J.G., Bulyk M.L., Harlow E., Marsischky G., Kolodner R.D.,
RA   LaBaer J.;
RT   "Approaching a complete repository of sequence-verified protein-encoding
RT   clones for Saccharomyces cerevisiae.";
RL   Genome Res. 17:536-543(2007).
RN   [4]
RP   DISRUPTION PHENOTYPE.
RX   PubMed=19300474; DOI=10.1371/journal.pgen.1000407;
RA   Hess D.C., Myers C.L., Huttenhower C., Hibbs M.A., Hayes A.P., Paw J.,
RA   Clore J.J., Mendoza R.M., Luis B.S., Nislow C., Giaever G., Costanzo M.,
RA   Troyanskaya O.G., Caudy A.A.;
RT   "Computationally driven, quantitative experiments discover genes required
RT   for mitochondrial biogenesis.";
RL   PLoS Genet. 5:E1000407-E1000407(2009).
CC   -!- DISRUPTION PHENOTYPE: Increases frequency of mitochondrial genome loss.
CC       {ECO:0000269|PubMed:19300474}.
CC   -!- SIMILARITY: Belongs to the AIM32 family. {ECO:0000305}.
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DR   EMBL; Z47816; CAA87824.1; -; Genomic_DNA.
DR   EMBL; AY557988; AAS56314.1; -; Genomic_DNA.
DR   EMBL; BK006946; DAA09849.1; -; Genomic_DNA.
DR   PIR; S50942; S50942.
DR   RefSeq; NP_013662.1; NM_001182408.1.
DR   AlphaFoldDB; Q04689; -.
DR   SMR; Q04689; -.
DR   BioGRID; 35118; 63.
DR   STRING; 4932.YML050W; -.
DR   TCDB; 3.A.30.1.1; the endoplasmic reticulum surface retrieval pathway (er-surf).
DR   MaxQB; Q04689; -.
DR   PaxDb; Q04689; -.
DR   PRIDE; Q04689; -.
DR   DNASU; 854955; -.
DR   EnsemblFungi; YML050W_mRNA; YML050W; YML050W.
DR   GeneID; 854955; -.
DR   KEGG; sce:YML050W; -.
DR   SGD; S000004514; AIM32.
DR   VEuPathDB; FungiDB:YML050W; -.
DR   eggNOG; ENOG502QS3W; Eukaryota.
DR   GeneTree; ENSGT00940000176686; -.
DR   HOGENOM; CLU_044499_1_0_1; -.
DR   InParanoid; Q04689; -.
DR   OMA; IPEMKIY; -.
DR   BioCyc; YEAST:G3O-32647-MON; -.
DR   PRO; PR:Q04689; -.
DR   Proteomes; UP000002311; Chromosome XIII.
DR   RNAct; Q04689; protein.
DR   CDD; cd03062; TRX_Fd_Sucrase; 1.
DR   InterPro; IPR009737; Aim32/Apd1-like.
DR   InterPro; IPR036249; Thioredoxin-like_sf.
DR   PANTHER; PTHR31902; PTHR31902; 1.
DR   Pfam; PF06999; Suc_Fer-like; 1.
DR   SUPFAM; SSF52833; SSF52833; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..311
FT                   /note="Altered inheritance of mitochondria protein 32"
FT                   /id="PRO_0000203255"
SQ   SEQUENCE   311 AA;  35977 MW;  6BFCFBE89422781F CRC64;
     MLRITVKTLQ QRASFHHSFK HISVPDLHTR AQNDQTNCYC QEINARLPSK TDPLDPHIKL
     PHRTPNYNKH VLLLSPGDRF AQPWKVAWNH NLDTNTNRPY NAISKLRSHL GGSPGILINA
     VHLQNEFIPR PKQHDEWLYF FVIPDMKLYV IKETDIEEFA SFLDEGAIQA PKLSFQDYLS
     GKAKASQQVH EVHHRKLTRF QGETFLRDWN LVCGHYKRDA KCGEMGPDII AAFQDEKLFP
     ENNLALISHI GGHIFAGNVI FYKLFGREKM QNKLDSLWFG KVYPHNLKLL CENLENGKII
     DEMYRGGISM N