ID   FATC_BACAN              Reviewed;         354 AA.
AC   Q81XB2; E9QQW5; E9QQW6; Q6HR47; Q6KKG4;
DT   25-APR-2018, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 141.
DE   RecName: Full=Petrobactin import system permease protein FatC {ECO:0000305};
GN   Name=fatC {ECO:0000303|PubMed:22429808};
GN   OrderedLocusNames=GBAA_5328 {ECO:0000312|EMBL:AAT34461.1};
OS   Bacillus anthracis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=1392;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames ancestor;
RX   PubMed=18952800; DOI=10.1128/jb.01347-08;
RA   Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D.,
RA   Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A.;
RT   "The complete genome sequence of Bacillus anthracis Ames 'Ancestor'.";
RL   J. Bacteriol. 191:445-446(2009).
RN   [2]
RP   FUNCTION, SUBUNIT, SUBCELLULAR LOCATION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=Sterne;
RX   PubMed=22429808; DOI=10.1111/j.1365-2958.2012.08028.x;
RA   Dixon S.D., Janes B.K., Bourgis A., Carlson P.E. Jr., Hanna P.C.;
RT   "Multiple ABC transporters are involved in the acquisition of petrobactin
RT   in Bacillus anthracis.";
RL   Mol. Microbiol. 84:370-382(2012).
CC   -!- FUNCTION: Part of an ABC transporter complex involved in ferric-
CC       petrobactin uptake. Probably responsible for the translocation of the
CC       substrate across the membrane. {ECO:0000269|PubMed:22429808}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (FatE),
CC       two transmembrane proteins (FatC and FatD) and a solute-binding protein
CC       (FpuA). {ECO:0000305|PubMed:22429808}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:22429808};
CC       Multi-pass membrane protein {ECO:0000255}.
CC   -!- DISRUPTION PHENOTYPE: A mutant lacking both fpuB and fatCD permeases is
CC       incapable of using petrobactin as an iron source and exhibits
CC       attenuated virulence in a murine model of inhalational anthrax
CC       infection. {ECO:0000269|PubMed:22429808}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. FecCD subfamily. {ECO:0000305}.
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DR   EMBL; AE017334; AAT34461.1; -; Genomic_DNA.
DR   RefSeq; WP_000631132.1; NZ_WXXJ01000007.1.
DR   AlphaFoldDB; Q81XB2; -.
DR   SMR; Q81XB2; -.
DR   STRING; 260799.BAS4951; -.
DR   DNASU; 1084831; -.
DR   EnsemblBacteria; AAT34461; AAT34461; GBAA_5328.
DR   GeneID; 45024935; -.
DR   KEGG; bar:GBAA_5328; -.
DR   PATRIC; fig|1392.230.peg.5246; -.
DR   HOGENOM; CLU_050494_0_0_9; -.
DR   OMA; LYMLIQT; -.
DR   Proteomes; UP000000594; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3470.10; -; 1.
DR   InterPro; IPR037294; ABC_BtuC-like.
DR   InterPro; IPR000522; ABC_transptr_permease_BtuC.
DR   PANTHER; PTHR30472; PTHR30472; 1.
DR   Pfam; PF01032; FecCD; 1.
DR   SUPFAM; SSF81345; SSF81345; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Ion transport; Iron; Iron transport; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..354
FT                   /note="Petrobactin import system permease protein FatC"
FT                   /id="PRO_0000443814"
FT   TRANSMEM        37..57
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        77..97
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        116..136
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        141..161
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        168..188
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        214..234
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        259..279
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        302..322
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        329..349
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   354 AA;  39001 MW;  904330694CB673EE CRC64;
     MITLDYRNKE NVEVDSSLHN ESRSASAFRS KKEARRYWIV LITLIALGLL SSYGLLVYNN
     PVPIDSPSFI PVVKRRIVAI VAMIIAAVCH SLSTVAFQSI TNNKIITPSL LGFESLYSAI
     QTSTVFFFGA SALINFNGIG SFLFQVVVMV FMSLILYGWL LSGKYGNLQL MLLVGIIIGT
     GLNSVSTFMR KLLAPSEFDI LQARLFGSVN HADPAYFPIV IPMIIIVAVL IFAHSKNLNV
     LSLGKDVATS FGVKYQPSVI YTLVLVAILM SISTALIGPL TFYGFLVATL SYQAAATYDH
     RYIFPMAFAI GFLIMTSAYF LMYHVFHAQG VVSVIIELFG GIIFLTIVLR KRAL