ID   FATD_BACAN              Reviewed;         334 AA.
AC   Q81XB1; E9R967; Q6KKG3;
DT   25-APR-2018, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 127.
DE   RecName: Full=Petrobactin import system permease protein FatD {ECO:0000305};
GN   Name=fatD {ECO:0000303|PubMed:22429808};
GN   OrderedLocusNames=GBAA_5329 {ECO:0000312|EMBL:AAT34462.1};
OS   Bacillus anthracis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=1392;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames ancestor;
RX   PubMed=18952800; DOI=10.1128/jb.01347-08;
RA   Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D.,
RA   Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A.;
RT   "The complete genome sequence of Bacillus anthracis Ames 'Ancestor'.";
RL   J. Bacteriol. 191:445-446(2009).
RN   [2]
RP   FUNCTION, SUBUNIT, SUBCELLULAR LOCATION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=Sterne;
RX   PubMed=22429808; DOI=10.1111/j.1365-2958.2012.08028.x;
RA   Dixon S.D., Janes B.K., Bourgis A., Carlson P.E. Jr., Hanna P.C.;
RT   "Multiple ABC transporters are involved in the acquisition of petrobactin
RT   in Bacillus anthracis.";
RL   Mol. Microbiol. 84:370-382(2012).
CC   -!- FUNCTION: Part of an ABC transporter complex involved in ferric-
CC       petrobactin uptake. Probably responsible for the translocation of the
CC       substrate across the membrane. {ECO:0000269|PubMed:22429808}.
CC   -!- SUBUNIT: The complex is composed of two ATP-binding proteins (FatE),
CC       two transmembrane proteins (FatC and FatD) and a solute-binding protein
CC       (FpuA). {ECO:0000305|PubMed:22429808}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305|PubMed:22429808};
CC       Multi-pass membrane protein {ECO:0000255}.
CC   -!- DISRUPTION PHENOTYPE: A mutant lacking both fpuB and fatCD permeases is
CC       incapable of using petrobactin as an iron source and exhibits
CC       attenuated virulence in a murine model of inhalational anthrax
CC       infection. {ECO:0000269|PubMed:22429808}.
CC   -!- SIMILARITY: Belongs to the binding-protein-dependent transport system
CC       permease family. FecCD subfamily. {ECO:0000305}.
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DR   EMBL; AE017334; AAT34462.1; -; Genomic_DNA.
DR   RefSeq; WP_011053273.1; NZ_VTZL01000005.1.
DR   AlphaFoldDB; Q81XB1; -.
DR   SMR; Q81XB1; -.
DR   STRING; 260799.BAS4952; -.
DR   DNASU; 1084833; -.
DR   EnsemblBacteria; AAT34462; AAT34462; GBAA_5329.
DR   KEGG; bar:GBAA_5329; -.
DR   HOGENOM; CLU_013016_3_0_9; -.
DR   Proteomes; UP000000594; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   GO; GO:0006811; P:ion transport; IEA:UniProtKB-KW.
DR   GO; GO:0055072; P:iron ion homeostasis; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.3470.10; -; 1.
DR   InterPro; IPR037294; ABC_BtuC-like.
DR   InterPro; IPR000522; ABC_transptr_permease_BtuC.
DR   PANTHER; PTHR30472; PTHR30472; 1.
DR   Pfam; PF01032; FecCD; 1.
DR   SUPFAM; SSF81345; SSF81345; 1.
PE   1: Evidence at protein level;
KW   Cell membrane; Ion transport; Iron; Iron transport; Membrane;
KW   Reference proteome; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..334
FT                   /note="Petrobactin import system permease protein FatD"
FT                   /id="PRO_0000443815"
FT   TRANSMEM        24..44
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        64..84
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        98..118
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        119..139
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        152..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        197..217
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        234..254
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        277..297
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        304..324
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   334 AA;  37020 MW;  59881C5CC46FF41B CRC64;
     MISRVENISQ PQFYNHNKIW TKPFIIAIIV VIILGIISLF TGVYDIRGQE DGMEMFFITR
     VPRTVALMLT GAAMAMAGLV MQLITQNRFV EPTTTGTIEW SSLGLLFVYL LFPAPTLVQR
     MTGAIIFSFI GTMIFFLFLR RVKLRSSLIV PIIGLMLGAV ISAVSTFLGL LFQMTQSIET
     WFVGSFANIQ VGRYEYLWLI VIVTLLIFMY ANRLTLAGLG EDVATSLGVN YNRIVLFGTA
     LISVAVGIVA AVIGNLPFLG LIVPNIVSMF RGDDLRSNLP WVCVIGMGTI TACDIISRTI
     IKPFELPVSL ILASVGAVVF ITILLRKRKP RRLR