ID   FAU1_AERPE              Reviewed;         471 AA.
AC   Q9Y9F2;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   14-NOV-2006, sequence version 2.
DT   25-MAY-2022, entry version 85.
DE   RecName: Full=Probable ribonuclease FAU-1 {ECO:0000255|HAMAP-Rule:MF_01910};
DE            EC=3.1.26.- {ECO:0000255|HAMAP-Rule:MF_01910};
DE   AltName: Full=RNA-binding protein FAU-1 {ECO:0000255|HAMAP-Rule:MF_01910};
GN   Name=fau-1 {ECO:0000255|HAMAP-Rule:MF_01910}; OrderedLocusNames=APE_2336.1;
OS   Aeropyrum pernix (strain ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 /
OS   K1).
OC   Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales;
OC   Desulfurococcaceae; Aeropyrum.
OX   NCBI_TaxID=272557;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 700893 / DSM 11879 / JCM 9820 / NBRC 100138 / K1;
RX   PubMed=10382966; DOI=10.1093/dnares/6.2.83;
RA   Kawarabayasi Y., Hino Y., Horikawa H., Yamazaki S., Haikawa Y., Jin-no K.,
RA   Takahashi M., Sekine M., Baba S., Ankai A., Kosugi H., Hosoyama A.,
RA   Fukui S., Nagai Y., Nishijima K., Nakazawa H., Takamiya M., Masuda S.,
RA   Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A.,
RA   Aoki K., Kubota K., Nakamura Y., Nomura N., Sako Y., Kikuchi H.;
RT   "Complete genome sequence of an aerobic hyper-thermophilic crenarchaeon,
RT   Aeropyrum pernix K1.";
RL   DNA Res. 6:83-101(1999).
CC   -!- FUNCTION: Probable RNase involved in rRNA stability through maturation
CC       and/or degradation of precursor rRNAs. Binds to RNA in loop regions
CC       with AU-rich sequences. {ECO:0000255|HAMAP-Rule:MF_01910}.
CC   -!- SIMILARITY: Belongs to the FAU-1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01910}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BA000002; BAA81348.2; -; Genomic_DNA.
DR   PIR; D72461; D72461.
DR   AlphaFoldDB; Q9Y9F2; -.
DR   SMR; Q9Y9F2; -.
DR   STRING; 272557.APE_2336.1; -.
DR   EnsemblBacteria; BAA81348; BAA81348; APE_2336.1.
DR   KEGG; ape:APE_2336.1; -.
DR   eggNOG; arCOG04307; Archaea.
DR   OMA; GTYVNVC; -.
DR   Proteomes; UP000002518; Chromosome.
DR   GO; GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:UniProtKB-UniRule.
DR   GO; GO:0035925; F:mRNA 3'-UTR AU-rich region binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.380.10; -; 1.
DR   HAMAP; MF_01910; RNA_binding_AU_1; 1.
DR   InterPro; IPR007295; DUF402.
DR   InterPro; IPR035930; FomD-like_sf.
DR   InterPro; IPR016730; RNA-bd_FAU-1.
DR   Pfam; PF04167; DUF402; 1.
DR   PIRSF; PIRSF018644; RNA-binding_FAU-1; 1.
DR   SUPFAM; SSF159234; SSF159234; 1.
PE   3: Inferred from homology;
KW   Endonuclease; Hydrolase; Nuclease; Reference proteome; RNA-binding;
KW   rRNA processing.
FT   CHAIN           1..471
FT                   /note="Probable ribonuclease FAU-1"
FT                   /id="PRO_0000334192"
SQ   SEQUENCE   471 AA;  51386 MW;  6564D4138BD4F717 CRC64;
     MLYAVRVRGI YATALVALAL KKGYLLSDLS KTMLSRVEVP VSTRPPNITV KHGEESRDEI
     VIHAFPYEAG ERFEADLLEE VGHAAVRRSL LGLRSVVDAR AAEGCRAEGP GGVLIIVKGG
     ECPQPGSMVR VTVVRSPPGS DVVEGRVGVE LTGLTVRVMH PGSGVRISRH LTSEDAAKAL
     KAVEASGIDL NQFSVHIRSG ARLASEGDIS DEIRRLAREA ERLWREGPGG EPAVLSRGEY
     LSLVYLPSTA KHVMDGLRTS LYPTVNNHHS LKSWSSEAEG LLTDFAEEGV REGLWGGEAG
     DLIVRFISSR LVGRTAVVLH RRPDGETIRL GPFRVSSYRP SSGRGGEIVL ERTFRSPGVY
     DGLGLERRPG DRGVTHVYMG DWLTIHEYYD KSGRLLGVYA NINTPPEVGF QGLKYLDLLV
     DVVKRPGEEP ETIDQGELEK ACRSGLLTDR LCEEAARQAE RASGLLQSRY P