ID   FAU1_HALS3              Reviewed;         471 AA.
AC   B0R8A2;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   25-MAY-2022, entry version 65.
DE   RecName: Full=Probable ribonuclease FAU-1 {ECO:0000255|HAMAP-Rule:MF_01910};
DE            EC=3.1.26.- {ECO:0000255|HAMAP-Rule:MF_01910};
DE   AltName: Full=RNA-binding protein FAU-1 {ECO:0000255|HAMAP-Rule:MF_01910};
GN   Name=fau-1 {ECO:0000255|HAMAP-Rule:MF_01910}; OrderedLocusNames=OE_4688F;
OS   Halobacterium salinarum (strain ATCC 29341 / DSM 671 / R1).
OC   Archaea; Euryarchaeota; Stenosarchaea group; Halobacteria; Halobacteriales;
OC   Halobacteriaceae; Halobacterium.
OX   NCBI_TaxID=478009;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29341 / DSM 671 / R1;
RX   PubMed=18313895; DOI=10.1016/j.ygeno.2008.01.001;
RA   Pfeiffer F., Schuster S.C., Broicher A., Falb M., Palm P., Rodewald K.,
RA   Ruepp A., Soppa J., Tittor J., Oesterhelt D.;
RT   "Evolution in the laboratory: the genome of Halobacterium salinarum strain
RT   R1 compared to that of strain NRC-1.";
RL   Genomics 91:335-346(2008).
CC   -!- FUNCTION: Probable RNase involved in rRNA stability through maturation
CC       and/or degradation of precursor rRNAs. Binds to RNA in loop regions
CC       with AU-rich sequences. {ECO:0000255|HAMAP-Rule:MF_01910}.
CC   -!- SIMILARITY: Belongs to the FAU-1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01910}.
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DR   EMBL; AM774415; CAP14971.1; -; Genomic_DNA.
DR   RefSeq; WP_010903965.1; NC_010364.1.
DR   AlphaFoldDB; B0R8A2; -.
DR   SMR; B0R8A2; -.
DR   PRIDE; B0R8A2; -.
DR   EnsemblBacteria; CAP14971; CAP14971; OE_4688F.
DR   GeneID; 5953469; -.
DR   KEGG; hsl:OE_4688F; -.
DR   HOGENOM; CLU_044303_0_0_2; -.
DR   OMA; GTYVNVC; -.
DR   PhylomeDB; B0R8A2; -.
DR   Proteomes; UP000001321; Chromosome.
DR   GO; GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:UniProtKB-UniRule.
DR   GO; GO:0035925; F:mRNA 3'-UTR AU-rich region binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.380.10; -; 1.
DR   HAMAP; MF_01910; RNA_binding_AU_1; 1.
DR   InterPro; IPR007295; DUF402.
DR   InterPro; IPR035930; FomD-like_sf.
DR   InterPro; IPR016730; RNA-bd_FAU-1.
DR   Pfam; PF04167; DUF402; 1.
DR   PIRSF; PIRSF018644; RNA-binding_FAU-1; 1.
DR   SUPFAM; SSF159234; SSF159234; 1.
PE   3: Inferred from homology;
KW   Endonuclease; Hydrolase; Nuclease; RNA-binding; rRNA processing.
FT   CHAIN           1..471
FT                   /note="Probable ribonuclease FAU-1"
FT                   /id="PRO_0000334196"
FT   DOMAIN          93..139
FT                   /note="S1 motif"
FT                   /evidence="ECO:0000255|HAMAP-Rule:MF_01910"
SQ   SEQUENCE   471 AA;  50002 MW;  0D2930961992CE62 CRC64;
     MTRVRVRGIY ATALTQLLRN AGLDVVAASP PIRARFPDAD LGAAEPHADI RMTPDRQGVG
     ITAHGDDHAR AVRAVVADLP RDTFVWPDPV PRGAVFDAAV DHTVGGGAIL DLGDDREAYL
     PFGAVDDHVT DGDTLRVAIR DPAPPWHDDR PTATSTITVS GALASLDRGV DALVAGAATD
     RAELARATEL LDPDIPDNWG VYWEYDGADA SLDARGTALD TLAARADRLE ATLADADGGD
     TPGLVAAPDT TLWAWFGRET RCALDDHRRT VAATMPGHHR IKAGSDAASD AVDFAEALGA
     SVDEFPFGAV TDQFGPSVGA SIEIQHGKPD GALISLGRGE VTDRSAENAR ITVEREMTGG
     GTYDALGVAR EAGDTATTRF TEGNWWYPTV YRSEDGERKG TYLNVCTPVE VFPDAVRYVD
     LHVDVIKHAD GAVEIVDREE LQDCVADGLV SEELAEKALS VAERVQSAVA E