ID   FAU1_IGNH4              Reviewed;         469 AA.
AC   A8AAJ1;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   23-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 63.
DE   RecName: Full=Probable ribonuclease FAU-1 {ECO:0000255|HAMAP-Rule:MF_01910};
DE            EC=3.1.26.- {ECO:0000255|HAMAP-Rule:MF_01910};
DE   AltName: Full=RNA-binding protein FAU-1 {ECO:0000255|HAMAP-Rule:MF_01910};
GN   Name=fau-1 {ECO:0000255|HAMAP-Rule:MF_01910}; OrderedLocusNames=Igni_0761;
OS   Ignicoccus hospitalis (strain KIN4/I / DSM 18386 / JCM 14125).
OC   Archaea; Crenarchaeota; Thermoprotei; Desulfurococcales;
OC   Desulfurococcaceae; Ignicoccus.
OX   NCBI_TaxID=453591;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=KIN4/I / DSM 18386 / JCM 14125;
RX   PubMed=19000309; DOI=10.1186/gb-2008-9-11-r158;
RA   Podar M., Anderson I., Makarova K.S., Elkins J.G., Ivanova N., Wall M.A.,
RA   Lykidis A., Mavromatis K., Sun H., Hudson M.E., Chen W., Deciu C.,
RA   Hutchison D., Eads J.R., Anderson A., Fernandes F., Szeto E., Lapidus A.,
RA   Kyrpides N.C., Saier M.H. Jr., Richardson P.M., Rachel R., Huber H.,
RA   Eisen J.A., Koonin E.V., Keller M., Stetter K.O.;
RT   "A genomic analysis of the archaeal system Ignicoccus hospitalis-
RT   Nanoarchaeum equitans.";
RL   Genome Biol. 9:R158.1-R158.18(2008).
CC   -!- FUNCTION: Probable RNase involved in rRNA stability through maturation
CC       and/or degradation of precursor rRNAs. Binds to RNA in loop regions
CC       with AU-rich sequences. {ECO:0000255|HAMAP-Rule:MF_01910}.
CC   -!- SIMILARITY: Belongs to the FAU-1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01910}.
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DR   EMBL; CP000816; ABU81943.1; -; Genomic_DNA.
DR   AlphaFoldDB; A8AAJ1; -.
DR   SMR; A8AAJ1; -.
DR   STRING; 453591.Igni_0761; -.
DR   EnsemblBacteria; ABU81943; ABU81943; Igni_0761.
DR   KEGG; iho:Igni_0761; -.
DR   eggNOG; arCOG04307; Archaea.
DR   HOGENOM; CLU_044303_0_0_2; -.
DR   OMA; GTYVNVC; -.
DR   PhylomeDB; A8AAJ1; -.
DR   Proteomes; UP000000262; Chromosome.
DR   GO; GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:UniProtKB-UniRule.
DR   GO; GO:0035925; F:mRNA 3'-UTR AU-rich region binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.380.10; -; 1.
DR   HAMAP; MF_01910; RNA_binding_AU_1; 1.
DR   InterPro; IPR007295; DUF402.
DR   InterPro; IPR035930; FomD-like_sf.
DR   InterPro; IPR016730; RNA-bd_FAU-1.
DR   Pfam; PF04167; DUF402; 1.
DR   SUPFAM; SSF159234; SSF159234; 1.
PE   3: Inferred from homology;
KW   Endonuclease; Hydrolase; Nuclease; Reference proteome; RNA-binding;
KW   rRNA processing.
FT   CHAIN           1..469
FT                   /note="Probable ribonuclease FAU-1"
FT                   /id="PRO_0000334199"
SQ   SEQUENCE   469 AA;  52802 MW;  2708A9856C73945B CRC64;
     MEKPRVRVRG IYATAVAKVL LDEGLELSDL SKKLKERIGH EGSPEPPHVT VKQSDDNPDQ
     LVIIGFPEET DKVIQTLRKS MPYSVHHLAR PNLHSAYVVE VDEECRTKLG EEEVRVKAKE
     CYDGKKLIAE VVRSRVFPTD KLVMEEGFRV IGLYAELVIG RGSGVTFSKH ITDLETKMLL
     MNLAAEVVRR GVKVHWRSSA KKAEPQVLLE ELEKLYDEAT KIMVKARDAD HGTEVYPGER
     LDVVELTLED KVILDEIRSK VVPTMPYHHS LKSGGDRMAA AVELGDKIAA SSEVKAESVI
     DYIIDLARDM KYLNIIHKKV DGAEYSLGRA RVRGNVDNYL VLERRSKDYG KYDGLDVVKE
     PGDLMITLVS PFSRYLIHAY YDQYGNEKGI YVNVNTGVEV GEGNVRYIDL EVDIIHKDGE
     WSVIDEDGLD RLPAPLRELA VAEVEKLLSH PDRIKEVVAN ARELLSAQL