ID   FAU1_PYRAE              Reviewed;         443 AA.
AC   Q8ZZX6;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 87.
DE   RecName: Full=Probable ribonuclease FAU-1 {ECO:0000255|HAMAP-Rule:MF_01910};
DE            EC=3.1.26.- {ECO:0000255|HAMAP-Rule:MF_01910};
DE   AltName: Full=RNA-binding protein FAU-1 {ECO:0000255|HAMAP-Rule:MF_01910};
GN   Name=fau-1 {ECO:0000255|HAMAP-Rule:MF_01910}; OrderedLocusNames=PAE0030;
OS   Pyrobaculum aerophilum (strain ATCC 51768 / DSM 7523 / JCM 9630 / CIP
OS   104966 / NBRC 100827 / IM2).
OC   Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC   Pyrobaculum.
OX   NCBI_TaxID=178306;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51768 / DSM 7523 / JCM 9630 / CIP 104966 / NBRC 100827 / IM2;
RX   PubMed=11792869; DOI=10.1073/pnas.241636498;
RA   Fitz-Gibbon S.T., Ladner H., Kim U.-J., Stetter K.O., Simon M.I.,
RA   Miller J.H.;
RT   "Genome sequence of the hyperthermophilic crenarchaeon Pyrobaculum
RT   aerophilum.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:984-989(2002).
CC   -!- FUNCTION: Probable RNase involved in rRNA stability through maturation
CC       and/or degradation of precursor rRNAs. Binds to RNA in loop regions
CC       with AU-rich sequences. {ECO:0000255|HAMAP-Rule:MF_01910}.
CC   -!- SIMILARITY: Belongs to the FAU-1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01910}.
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DR   EMBL; AE009441; AAL62513.1; -; Genomic_DNA.
DR   AlphaFoldDB; Q8ZZX6; -.
DR   STRING; 178306.PAE0030; -.
DR   PRIDE; Q8ZZX6; -.
DR   EnsemblBacteria; AAL62513; AAL62513; PAE0030.
DR   KEGG; pai:PAE0030; -.
DR   PATRIC; fig|178306.9.peg.21; -.
DR   eggNOG; arCOG04307; Archaea.
DR   HOGENOM; CLU_044303_0_0_2; -.
DR   InParanoid; Q8ZZX6; -.
DR   OMA; GTYVNVC; -.
DR   Proteomes; UP000002439; Chromosome.
DR   GO; GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:UniProtKB-UniRule.
DR   GO; GO:0035925; F:mRNA 3'-UTR AU-rich region binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.380.10; -; 1.
DR   HAMAP; MF_01910; RNA_binding_AU_1; 1.
DR   InterPro; IPR007295; DUF402.
DR   InterPro; IPR035930; FomD-like_sf.
DR   InterPro; IPR016730; RNA-bd_FAU-1.
DR   Pfam; PF04167; DUF402; 1.
DR   PIRSF; PIRSF018644; RNA-binding_FAU-1; 1.
DR   SUPFAM; SSF159234; SSF159234; 1.
PE   3: Inferred from homology;
KW   Endonuclease; Hydrolase; Nuclease; Reference proteome; RNA-binding;
KW   rRNA processing.
FT   CHAIN           1..443
FT                   /note="Probable ribonuclease FAU-1"
FT                   /id="PRO_0000334202"
SQ   SEQUENCE   443 AA;  48852 MW;  47F582CCC518FFBF CRC64;
     MYKVRIRGIF ATALTKLALE WGFKIVQPTG KILQRFQIEA DYSPPDLTVK DHESKTGVVV
     LGKCEAFESF LQRLGESLDP IVARARAGVK EVFSGKAVGE HEVEGPRGEV FKVPARYVLT
     PGGTGVFTVV KPPVGPVSGV AAPEIAVEGD YVELNTSGRV TFSEHIPQED RLRLGILAET
     RLKQYASIGL RFKSSAKYAD EEQIIKEAEV LYRELLQLSH GGPPGAVLRR GNCFAVVLFD
     RRSKEVLDSA RASAVPTVRG HHALRAQGLG KCLDLLDYTG ADVYEKAVEF LSRGPVLIYH
     VKPWGEVVKM KGEALGVKNG VLVVKRPLKP GGVLDGIGVR IERGFYALTC IPRDANYVVH
     TYYDGSNNVV GTYININTTP EWGRRVIYID LLVDKTYAGG VEKVLDVDEF EKYKEYFPQR
     LRNPLQLAPS GRLECTAEGL VVR