ID   FAU1_PYRIL              Reviewed;         448 AA.
AC   A1RQK4;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   06-FEB-2007, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Probable ribonuclease FAU-1 {ECO:0000255|HAMAP-Rule:MF_01910};
DE            EC=3.1.26.- {ECO:0000255|HAMAP-Rule:MF_01910};
DE   AltName: Full=RNA-binding protein FAU-1 {ECO:0000255|HAMAP-Rule:MF_01910};
GN   Name=fau-1 {ECO:0000255|HAMAP-Rule:MF_01910}; OrderedLocusNames=Pisl_0052;
OS   Pyrobaculum islandicum (strain DSM 4184 / JCM 9189 / GEO3).
OC   Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC   Pyrobaculum.
OX   NCBI_TaxID=384616;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 4184 / JCM 9189 / GEO3;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C.,
RA   Glavina del Rio T., Dalin E., Tice H., Pitluck S., Meincke L., Brettin T.,
RA   Bruce D., Han C., Tapia R., Gilna P., Schmutz J., Larimer F., Land M.,
RA   Hauser L., Kyrpides N., Mikhailova N., Lowe T., Richardson P.;
RT   "Complete sequence of Pyrobaculum islandicum DSM 4184.";
RL   Submitted (DEC-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable RNase involved in rRNA stability through maturation
CC       and/or degradation of precursor rRNAs. Binds to RNA in loop regions
CC       with AU-rich sequences. {ECO:0000255|HAMAP-Rule:MF_01910}.
CC   -!- SIMILARITY: Belongs to the FAU-1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01910}.
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DR   EMBL; CP000504; ABL87236.1; -; Genomic_DNA.
DR   RefSeq; WP_011761813.1; NC_008701.1.
DR   AlphaFoldDB; A1RQK4; -.
DR   STRING; 384616.Pisl_0052; -.
DR   EnsemblBacteria; ABL87236; ABL87236; Pisl_0052.
DR   GeneID; 4616355; -.
DR   KEGG; pis:Pisl_0052; -.
DR   eggNOG; arCOG04307; Archaea.
DR   HOGENOM; CLU_044303_0_0_2; -.
DR   OMA; GTYVNVC; -.
DR   OrthoDB; 83570at2157; -.
DR   Proteomes; UP000002595; Chromosome.
DR   GO; GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:UniProtKB-UniRule.
DR   GO; GO:0035925; F:mRNA 3'-UTR AU-rich region binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.380.10; -; 1.
DR   HAMAP; MF_01910; RNA_binding_AU_1; 1.
DR   InterPro; IPR007295; DUF402.
DR   InterPro; IPR035930; FomD-like_sf.
DR   InterPro; IPR016730; RNA-bd_FAU-1.
DR   Pfam; PF04167; DUF402; 1.
DR   SUPFAM; SSF159234; SSF159234; 1.
PE   3: Inferred from homology;
KW   Endonuclease; Hydrolase; Nuclease; RNA-binding; rRNA processing.
FT   CHAIN           1..448
FT                   /note="Probable ribonuclease FAU-1"
FT                   /id="PRO_0000334205"
FT   REGION          426..448
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   448 AA;  49351 MW;  F649EF3BFDAC5B11 CRC64;
     MFKARIRGIY ATALTKLALD WGFEIVQPTQ QIINRFGLKP DYSPPDITVK DHESKTGVVT
     IGECQAVDYF LERLRQYVDP VIAKASAGLH DVFIGRVVGE GLVEAPGGQL MEVPRRYVVQ
     PGSTSVFTVV KPPMGPFRGV AVPEIVVEGK LLELNTTGRV SYSRHIAEQE RLRLRILAET
     KLKNYASIGL RFKSSAKYAS EDELAKEAEE LYKEMLKISQ GGPPGTLLRR GKCIAVVLFD
     RQAKFKLDEA RAAVVPTIRG HHALRGQGLG KCLDLLDYAG ADVYEKAVEF LARGRVVIYH
     VKPWGEVIKM RGEVVKISDD VLVVKRPLRP GGVLDGIGAK IEPGTYALTC VPKSGGYVVH
     SYYSASGVYL GTYVNINTDP EWGRRIIYID LLVDKAYGLD GVERVLDADE LQRYAHMLPE
     RLRRPEAPGG KICTSEGLTS ALPQSSSA