ID   FAU1_PYRNV              Reviewed;         447 AA.
AC   B1YDP2;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Probable ribonuclease FAU-1 {ECO:0000255|HAMAP-Rule:MF_01910};
DE            EC=3.1.26.- {ECO:0000255|HAMAP-Rule:MF_01910};
DE   AltName: Full=RNA-binding protein FAU-1 {ECO:0000255|HAMAP-Rule:MF_01910};
GN   Name=fau-1 {ECO:0000255|HAMAP-Rule:MF_01910}; OrderedLocusNames=Tneu_0970;
OS   Pyrobaculum neutrophilum (strain DSM 2338 / JCM 9278 / NBRC 100436 /
OS   V24Sta) (Thermoproteus neutrophilus).
OC   Archaea; Crenarchaeota; Thermoprotei; Thermoproteales; Thermoproteaceae;
OC   Pyrobaculum.
OX   NCBI_TaxID=444157;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 2338 / JCM 9278 / NBRC 100436 / V24Sta;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H.,
RA   Bruce D., Goodwin L., Pitluck S., Sims D., Brettin T., Detter J.C., Han C.,
RA   Kuske C.R., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N.,
RA   Mikhailova N., Biddle J.F., Zhang Z., Fitz-Gibbon S.T., Lowe T.M.,
RA   Saltikov C., House C.H., Richardson P.;
RT   "Complete sequence of Thermoproteus neutrophilus V24Sta.";
RL   Submitted (MAR-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Probable RNase involved in rRNA stability through maturation
CC       and/or degradation of precursor rRNAs. Binds to RNA in loop regions
CC       with AU-rich sequences. {ECO:0000255|HAMAP-Rule:MF_01910}.
CC   -!- SIMILARITY: Belongs to the FAU-1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01910}.
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DR   EMBL; CP001014; ACB39905.1; -; Genomic_DNA.
DR   AlphaFoldDB; B1YDP2; -.
DR   STRING; 444157.Tneu_0970; -.
DR   EnsemblBacteria; ACB39905; ACB39905; Tneu_0970.
DR   KEGG; tne:Tneu_0970; -.
DR   eggNOG; arCOG04307; Archaea.
DR   HOGENOM; CLU_044303_0_0_2; -.
DR   OMA; GTYVNVC; -.
DR   Proteomes; UP000001694; Chromosome.
DR   GO; GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:UniProtKB-UniRule.
DR   GO; GO:0035925; F:mRNA 3'-UTR AU-rich region binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.380.10; -; 1.
DR   HAMAP; MF_01910; RNA_binding_AU_1; 1.
DR   InterPro; IPR007295; DUF402.
DR   InterPro; IPR035930; FomD-like_sf.
DR   InterPro; IPR016730; RNA-bd_FAU-1.
DR   Pfam; PF04167; DUF402; 1.
DR   SUPFAM; SSF159234; SSF159234; 1.
PE   3: Inferred from homology;
KW   Endonuclease; Hydrolase; Nuclease; RNA-binding; rRNA processing.
FT   CHAIN           1..447
FT                   /note="Probable ribonuclease FAU-1"
FT                   /id="PRO_1000188788"
FT   REGION          424..447
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   447 AA;  48682 MW;  AA0E7CDA27C25B80 CRC64;
     MFRARIRGIY ATALTKLALD WGFKVVQPTP QIAERFGLRP DPSPPDVTVK DHESKTGVVA
     IGDCPAVDHL LERLREYADP VVAKASAGLH DVFVGRVVGE GLVEGPGGLM EVPGRYVLQP
     GAASVFTVVK PPVGPLRGVA VPEIVVDGKL LELNTTGRVA YSRHIGEEER LRLRILAETR
     LKAYASIGLR FKSSAKYAGE EELAREAEEL YRELLRLSQG GPPGALLRRG RCLAVVLFDK
     RAKFKLDEAR AAVVPTVRGH HALRGQGLGR CLDLLDHVGA DVYERAAAFL ARGRVAIYHV
     KPWGEVVKMR GEVVKALEDV LVVKRTLKPG GVLDGIGARI EPGTYALTCV PRSGGYVVHS
     YYSASGVYLG TYVNANTEPE WGRRVVYIDL LVDKAYGPDG VERVLDEEEL QRYAHMLPER
     LRRPEAPGGK ICTPEGLTSA PPRSSSA