ID   FAU1_SACS2              Reviewed;         424 AA.
AC   Q97Z43;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2001, sequence version 1.
DT   25-MAY-2022, entry version 93.
DE   RecName: Full=Probable ribonuclease FAU-1 {ECO:0000255|HAMAP-Rule:MF_01910};
DE            EC=3.1.26.- {ECO:0000255|HAMAP-Rule:MF_01910};
DE   AltName: Full=RNA-binding protein FAU-1 {ECO:0000255|HAMAP-Rule:MF_01910};
GN   Name=fau-1 {ECO:0000255|HAMAP-Rule:MF_01910}; OrderedLocusNames=SSO1093;
OS   Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2)
OS   (Sulfolobus solfataricus).
OC   Archaea; Crenarchaeota; Thermoprotei; Sulfolobales; Sulfolobaceae;
OC   Saccharolobus.
OX   NCBI_TaxID=273057;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 35092 / DSM 1617 / JCM 11322 / P2;
RX   PubMed=11427726; DOI=10.1073/pnas.141222098;
RA   She Q., Singh R.K., Confalonieri F., Zivanovic Y., Allard G., Awayez M.J.,
RA   Chan-Weiher C.C.-Y., Clausen I.G., Curtis B.A., De Moors A., Erauso G.,
RA   Fletcher C., Gordon P.M.K., Heikamp-de Jong I., Jeffries A.C., Kozera C.J.,
RA   Medina N., Peng X., Thi-Ngoc H.P., Redder P., Schenk M.E., Theriault C.,
RA   Tolstrup N., Charlebois R.L., Doolittle W.F., Duguet M., Gaasterland T.,
RA   Garrett R.A., Ragan M.A., Sensen C.W., Van der Oost J.;
RT   "The complete genome of the crenarchaeon Sulfolobus solfataricus P2.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:7835-7840(2001).
CC   -!- FUNCTION: Probable RNase involved in rRNA stability through maturation
CC       and/or degradation of precursor rRNAs. Binds to RNA in loop regions
CC       with AU-rich sequences. {ECO:0000255|HAMAP-Rule:MF_01910}.
CC   -!- SIMILARITY: Belongs to the FAU-1 family. {ECO:0000255|HAMAP-
CC       Rule:MF_01910}.
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DR   EMBL; AE006641; AAK41353.1; -; Genomic_DNA.
DR   PIR; B99262; B99262.
DR   RefSeq; WP_009989727.1; NC_002754.1.
DR   AlphaFoldDB; Q97Z43; -.
DR   SMR; Q97Z43; -.
DR   STRING; 273057.SSO1093; -.
DR   EnsemblBacteria; AAK41353; AAK41353; SSO1093.
DR   GeneID; 44130028; -.
DR   KEGG; sso:SSO1093; -.
DR   PATRIC; fig|273057.12.peg.1091; -.
DR   eggNOG; arCOG04307; Archaea.
DR   HOGENOM; CLU_044303_0_0_2; -.
DR   InParanoid; Q97Z43; -.
DR   OMA; GTYVNVC; -.
DR   PhylomeDB; Q97Z43; -.
DR   Proteomes; UP000001974; Chromosome.
DR   GO; GO:0016891; F:endoribonuclease activity, producing 5'-phosphomonoesters; IEA:UniProtKB-UniRule.
DR   GO; GO:0035925; F:mRNA 3'-UTR AU-rich region binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006364; P:rRNA processing; IEA:UniProtKB-UniRule.
DR   Gene3D; 2.40.380.10; -; 1.
DR   HAMAP; MF_01910; RNA_binding_AU_1; 1.
DR   InterPro; IPR007295; DUF402.
DR   InterPro; IPR035930; FomD-like_sf.
DR   InterPro; IPR016730; RNA-bd_FAU-1.
DR   Pfam; PF04167; DUF402; 1.
DR   PIRSF; PIRSF018644; RNA-binding_FAU-1; 1.
DR   SUPFAM; SSF159234; SSF159234; 1.
PE   3: Inferred from homology;
KW   Endonuclease; Hydrolase; Nuclease; Reference proteome; RNA-binding;
KW   rRNA processing.
FT   CHAIN           1..424
FT                   /note="Probable ribonuclease FAU-1"
FT                   /id="PRO_0000334212"
SQ   SEQUENCE   424 AA;  49257 MW;  54938B54AA4406A1 CRC64;
     MKGRVRIRGI YATALTSIFS SLSYEIVQQS VEISERFMQE INNLSADITI KDFEDDRGKI
     IVMGNGIIED DLRNVFKYSF HWRSPVKLYS VIEIDESCTY ANFKVEPCLR EGIVIKPPYD
     GKIILSETKA VSKYAIVWRG KGITTFSEHI VDEEEKMRLL TLSLPLNRKG YNVKWRSNAK
     YVALNELKED LERLILRYEN REFRDQGEDF YLITLSLPDK LYLDEVRKNV VDTVKYHHML
     KLSYNREVDS LEKDKKGSLG KLLEGLISDF LKIEHIKADG KVIYLRGGKV IEKEVNDNGY
     RIVLRREFEG NGILDGIGKK IEEGDYDIVE YNSDKWYQIH KYYSGIDNSL KGVYINISTP
     PELLRGKIRY LDLEIDIAIR DSEIALLDED ELNKKSIYMP SSLVNKAKEV VNYLINRIQQ
     NKLS