FAZ1_TRYB9
ID FAZ1_TRYB9 Reviewed; 1748 AA.
AC C9ZN16;
DT 14-DEC-2011, integrated into UniProtKB/Swiss-Prot.
DT 24-NOV-2009, sequence version 1.
DT 25-MAY-2022, entry version 22.
DE RecName: Full=Flagellar attachment zone protein 1 {ECO:0000250|UniProtKB:Q585H6};
GN ORFNames=TbgDal_IV3690;
OS Trypanosoma brucei gambiense (strain MHOM/CI/86/DAL972).
OC Eukaryota; Discoba; Euglenozoa; Kinetoplastea; Metakinetoplastina;
OC Trypanosomatida; Trypanosomatidae; Trypanosoma.
OX NCBI_TaxID=679716;
RN [1] {ECO:0000312|EMBL:CBH10670.1}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MHOM/CI/86/DAL972;
RX PubMed=20404998; DOI=10.1371/journal.pntd.0000658;
RA Jackson A.P., Sanders M., Berry A., McQuillan J., Aslett M.A., Quail M.A.,
RA Chukualim B., Capewell P., MacLeod A., Melville S.E., Gibson W.,
RA Barry J.D., Berriman M., Hertz-Fowler C.;
RT "The genome sequence of Trypanosoma brucei gambiense, causative agent of
RT chronic human african trypanosomiasis.";
RL PLoS Negl. Trop. Dis. 4:E658-E658(2010).
CC -!- FUNCTION: A component of FAZ filament that is required for correct FAZ
CC assembly and attachment. Not essential for new flagellum growth (By
CC similarity). {ECO:0000250|UniProtKB:Q585H6}.
CC -!- SUBCELLULAR LOCATION: Cell projection, cilium, flagellum
CC {ECO:0000250|UniProtKB:Q585H6}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; FN554967; CBH10670.1; -; Genomic_DNA.
DR RefSeq; XP_011772958.1; XM_011774656.1.
DR AlphaFoldDB; C9ZN16; -.
DR SMR; C9ZN16; -.
DR GeneID; 23859805; -.
DR KEGG; tbg:TbgDal_IV3690; -.
DR VEuPathDB; TriTrypDB:Tbg972.4.3690; -.
DR OrthoDB; 255960at2759; -.
DR Proteomes; UP000002316; Chromosome 4.
DR GO; GO:0031514; C:motile cilium; IEA:UniProtKB-SubCell.
PE 3: Inferred from homology;
KW Cell projection; Cilium; Coiled coil; Flagellum; Repeat.
FT CHAIN 1..1748
FT /note="Flagellar attachment zone protein 1"
FT /id="PRO_0000414607"
FT REPEAT 1012..1025
FT /note="1"
FT /evidence="ECO:0000255"
FT REPEAT 1026..1039
FT /note="2"
FT /evidence="ECO:0000255"
FT REPEAT 1040..1053
FT /note="3"
FT /evidence="ECO:0000255"
FT REPEAT 1054..1067
FT /note="4"
FT /evidence="ECO:0000255"
FT REPEAT 1068..1081
FT /note="5"
FT /evidence="ECO:0000255"
FT REPEAT 1082..1095
FT /note="6"
FT /evidence="ECO:0000255"
FT REPEAT 1096..1109
FT /note="7"
FT /evidence="ECO:0000255"
FT REPEAT 1110..1123
FT /note="8"
FT /evidence="ECO:0000255"
FT REPEAT 1124..1137
FT /note="9"
FT /evidence="ECO:0000255"
FT REPEAT 1138..1151
FT /note="10"
FT /evidence="ECO:0000255"
FT REPEAT 1152..1165
FT /note="11"
FT /evidence="ECO:0000255"
FT REPEAT 1166..1179
FT /note="12"
FT /evidence="ECO:0000255"
FT REPEAT 1180..1193
FT /note="13"
FT /evidence="ECO:0000255"
FT REPEAT 1194..1207
FT /note="14"
FT /evidence="ECO:0000255"
FT REPEAT 1208..1221
FT /note="15"
FT /evidence="ECO:0000255"
FT REPEAT 1222..1235
FT /note="16"
FT /evidence="ECO:0000255"
FT REPEAT 1236..1249
FT /note="17"
FT /evidence="ECO:0000255"
FT REPEAT 1250..1263
FT /note="18"
FT /evidence="ECO:0000255"
FT REPEAT 1264..1277
FT /note="19"
FT /evidence="ECO:0000255"
FT REPEAT 1278..1291
FT /note="20"
FT /evidence="ECO:0000255"
FT REPEAT 1292..1305
FT /note="21"
FT /evidence="ECO:0000255"
FT REPEAT 1306..1319
FT /note="22"
FT /evidence="ECO:0000255"
FT REPEAT 1320..1333
FT /note="23"
FT /evidence="ECO:0000255"
FT REPEAT 1334..1347
FT /note="24"
FT /evidence="ECO:0000255"
FT REPEAT 1348..1361
FT /note="25"
FT /evidence="ECO:0000255"
FT REPEAT 1362..1375
FT /note="26"
FT /evidence="ECO:0000255"
FT REPEAT 1376..1389
FT /note="27"
FT /evidence="ECO:0000255"
FT REPEAT 1390..1403
FT /note="28"
FT /evidence="ECO:0000255"
FT REPEAT 1404..1417
FT /note="29"
FT /evidence="ECO:0000255"
FT REPEAT 1418..1431
FT /note="30"
FT /evidence="ECO:0000255"
FT REPEAT 1432..1445
FT /note="31"
FT /evidence="ECO:0000255"
FT REPEAT 1446..1459
FT /note="32"
FT /evidence="ECO:0000255"
FT REPEAT 1460..1473
FT /note="33"
FT /evidence="ECO:0000255"
FT REPEAT 1474..1487
FT /note="34"
FT /evidence="ECO:0000255"
FT REPEAT 1488..1501
FT /note="35"
FT /evidence="ECO:0000255"
FT REPEAT 1502..1515
FT /note="36"
FT /evidence="ECO:0000255"
FT REPEAT 1516..1529
FT /note="37"
FT /evidence="ECO:0000255"
FT REPEAT 1530..1543
FT /note="38"
FT /evidence="ECO:0000255"
FT REPEAT 1544..1557
FT /note="39"
FT /evidence="ECO:0000255"
FT REPEAT 1558..1571
FT /note="40"
FT /evidence="ECO:0000255"
FT REPEAT 1572..1585
FT /note="41"
FT /evidence="ECO:0000255"
FT REGION 1012..1529
FT /note="41 X 14 AA tandem repeats of E-E-L-E-L-K-[VA]-A-E-N-
FT E-K-L-A"
FT /evidence="ECO:0000255"
FT COILED 613..657
FT /evidence="ECO:0000255"
FT COILED 684..864
FT /evidence="ECO:0000255"
FT COILED 903..1663
FT /evidence="ECO:0000255"
SQ SEQUENCE 1748 AA; 198586 MW; 2C157ABD0E99C125 CRC64;
MALLNVISEN PLTLQPGQVI AFDHLANGEH WQWALGTVVS SDKHVVVVEQ WAVNEGSCET
LKHNISSEIQ KEMKRMGVFQ EQLSSARDKL AAIRSENEDR VSAARAVFED AKARVASVDE
VHMREVTSQA CPSPVAVEVL KCVLALAQND PTVTNCSTWD DIRMEYRRPN AIADFISADI
TGKTYPNAEE ICSSLNEQRL SSLAASRDSE AISSLHHWVL SALAYQEAYC RLTTDTRVQE
QNDAIANCIA GMKGCRLKVM KLKEELERGG TPTFGGQLTS FTKTSVQLKA PLSSVISIVG
VDPSAQDCVL TDDEVGLILD KAEQTRLQIN DHFSHLSNSY MEAMAELHCL SMYTSELEER
RLNLQERFVF SLFTNAGKTN APRRERIETD VGLRSVEAPR GDSANNIKDL QEIIKELSSH
DERWMYRNEP TVTTKHRKSY PGREWSKVVE RKPEELLSTF RTEQAAACHV PEDAIRNIEF
TATSEKLQVS FDVQHPVKQT AAEINKRLQE FPSRGMDRML CDVDQPKKGL DRAIVEVCRA
FDLREHAFRG MTFDKFIEEV AMKGRVGDKD AYESEIGDLL MLLDKIHNEN RSLQYTLEKS
AEEFRRQTAS TMREQESLRQ RNGELHAEIG RLRDLVEKLR DLADNQASEL ELLKLQKTQA
NQIRAQRNLS TFRGDDTAEP VYCVTLDELR EQTEHCDQVE RELERQREQC QNLLNAQDDL
LAELSGVSEE KEKLEAECER LEAELRQMEE KSRLSEQGLS EMTQRLEEKQ AEIEGLLENL
EQLDEQLEAL RAAEKSAQAH IEARDREISD LQQRLEGEID DHIKTTALLE ELRKHYNNLE
ELFDKQEAEL MAYREKRQNA HKVRSLEPTL RPIGTQTKPF QEVVSADEIS SEPLLSVTLD
EYNDHMHRSN QFQQENDLLR QQLQQANDER ENLHDRLEQL MAENQSLSEQ LHNMHEELER
EERDRSGVTL QNERLAEEIQ RKTAENEQLV LENNKSRSDI RNLNVQVQRL MEELELKAAE
NEKLAEELEL KAAENEKLAE ELELKAAENE KLAEALDLKA AENEKLAEEL ELKVAENEKL
AEELELKVAE NEKLAEELEL KAAENEKLAE ELELKAAENE KLAEELELKA AENEKLAEEL
ELKAAENEKL AEALDLKAAE NEKLAEELDL KAAENEKLAE ELELKVAENE KLAEELELKA
AENEKLAEEL ELKAAENEKL AEELELKAAE NEKLAEELEL KVAENEKLAE ELELKAAENE
KLAEELELKA AENEKLAEEL ELKAAENEKL AEELELKVAE NEKLAEELEL KAAENEKLAE
ELELKAAENE KLAEELELKA AENEKLAEEL ELKAAENEKL AEELELKAAE NEKLAEELEL
KAAENEKLAE ELELKAAENE KLAEELELKA AENEKLAEEL ELKAAENEKL AEELELKAAE
NEKLAEELEL KAAENEKLAE ELELKAAENE KLAEELELKA AENEKLAEEL ELKAAENEKL
AEELELKAAE NEKLAEELEL KAAENEKLAE ELELKAAENE KLAEELELKV AENEKLAEEL
ELKVAENEKL AEELELKVAE NKRLAEEVTQ RLSEKELLAE DTSARLLEAD SANSALQCKV
KHLEEKLTLL SSEKETALAT LEAEIVDLLT QLKGLNGTNS ALESLCASKE KELVFLREHC
ELWTDPTTKK EKVITRHVKV FDGNEWMKLI TDRPEALMSA FVIDAGNACH VPGDQIHEVS
FLNNKEKH
