FB140_ARATH
ID FB140_ARATH Reviewed; 422 AA.
AC Q84WW1; Q8LCI5; Q9C7A1; Q9LHH2;
DT 06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2003, sequence version 1.
DT 03-AUG-2022, entry version 108.
DE RecName: Full=F-box protein At3g12350;
GN OrderedLocusNames=At3g12350; ORFNames=MQC3.17, T2E22.32;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q84WW1-1; Sequence=Displayed;
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG51006.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=BAB03143.1; Type=Erroneous gene model prediction; Note=The predicted gene At3g12350 has been split into 2 genes: At3g12350 and At3g12360.; Evidence={ECO:0000305};
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AP002047; BAB03143.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AC069474; AAG51006.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE75186.1; -; Genomic_DNA.
DR EMBL; BT001925; AAN71924.1; -; mRNA.
DR EMBL; AY086584; AAM63646.1; -; mRNA.
DR RefSeq; NP_566421.1; NM_112070.4. [Q84WW1-1]
DR AlphaFoldDB; Q84WW1; -.
DR BioGRID; 5747; 3.
DR IntAct; Q84WW1; 3.
DR STRING; 3702.AT3G12350.1; -.
DR PaxDb; Q84WW1; -.
DR PRIDE; Q84WW1; -.
DR ProteomicsDB; 231015; -. [Q84WW1-1]
DR EnsemblPlants; AT3G12350.1; AT3G12350.1; AT3G12350. [Q84WW1-1]
DR GeneID; 820413; -.
DR Gramene; AT3G12350.1; AT3G12350.1; AT3G12350. [Q84WW1-1]
DR KEGG; ath:AT3G12350; -.
DR Araport; AT3G12350; -.
DR TAIR; locus:2092487; AT3G12350.
DR eggNOG; ENOG502QTTY; Eukaryota.
DR HOGENOM; CLU_651088_0_0_1; -.
DR OMA; CQRRWGS; -.
DR OrthoDB; 596217at2759; -.
DR PhylomeDB; Q84WW1; -.
DR PRO; PR:Q84WW1; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q84WW1; baseline and differential.
DR Genevisible; Q84WW1; AT.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR Pfam; PF12937; F-box-like; 1.
DR SUPFAM; SSF81383; SSF81383; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 2: Evidence at transcript level;
KW Alternative splicing; Reference proteome.
FT CHAIN 1..422
FT /note="F-box protein At3g12350"
FT /id="PRO_0000274951"
FT DOMAIN 5..52
FT /note="F-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT REGION 197..216
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 226..252
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 233..252
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 274
FT /note="G -> C (in Ref. 5; AAM63646)"
FT /evidence="ECO:0000305"
FT CONFLICT 284
FT /note="I -> M (in Ref. 5; AAM63646)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 422 AA; 47756 MW; 13C8580242432D0A CRC64;
MATFALPFCE IPEDLQLRIL SLLTPAEISS FACTSKRFAS LCQEDGKIWH VMCDQRWGKK
TKIQKWANGQ IPYRHLYKTL KGLENLIGFW RLCGRANPAA SSPPLVFFDW GSSFILGSRV
LSTGDDTYEV KKTPFLLMGI SPEGRSENFL DLVGGNLRSV DDDLKELEAS NNLVSVDVNF
MGNGHIMVEE NRCFTNNNRR EDQRSSGDES DDLISSPNFS EMYTQLANKT SPGGDRRRQK
RKEKERQASR TKWEPEHFLK VADCSPTPTR PLQGLWKGFC EGSIELYLVK YDEVGGIICR
KVEDLSLSRY TPPVFWTPKH TFIRSPFSAE EELLLNSRIH ISPFAEVHEN VVSGMLYMKS
SCDLVLPGEP GNGIGFLRGE GRVWLYDNGT FGFGFLRDQF IIDLKRVALE DGCLADEVEA
CM
