ID   FB224_CAEEL             Reviewed;         384 AA.
AC   Q09336;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   21-SEP-2011, sequence version 3.
DT   03-AUG-2022, entry version 103.
DE   RecName: Full=F-box A protein 224;
GN   Name=fbxa-224; ORFNames=ZK1290.9;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
CC   -!- SIMILARITY: Belongs to the FTH family. {ECO:0000305}.
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DR   EMBL; FO080700; CCD65947.1; -; Genomic_DNA.
DR   PIR; T34508; T34508.
DR   RefSeq; NP_495583.3; NM_063182.3.
DR   AlphaFoldDB; Q09336; -.
DR   STRING; 6239.ZK1290.9; -.
DR   PaxDb; Q09336; -.
DR   EnsemblMetazoa; ZK1290.9.1; ZK1290.9.1; WBGene00022890.
DR   GeneID; 191557; -.
DR   KEGG; cel:CELE_ZK1290.9; -.
DR   CTD; 191557; -.
DR   WormBase; ZK1290.9; CE44940; WBGene00022890; fbxa-224.
DR   eggNOG; ENOG502RT5I; Eukaryota.
DR   GeneTree; ENSGT00940000154228; -.
DR   HOGENOM; CLU_030831_3_3_1; -.
DR   InParanoid; Q09336; -.
DR   OMA; FISECVE; -.
DR   OrthoDB; 1819772at2759; -.
DR   PhylomeDB; Q09336; -.
DR   PRO; PR:Q09336; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00022890; Expressed in pharyngeal muscle cell (C elegans) and 2 other tissues.
DR   InterPro; IPR002900; DUF38_CAE_spp.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR040161; FB155/FB224.
DR   InterPro; IPR041426; Mos1_HTH.
DR   PANTHER; PTHR23015; PTHR23015; 1.
DR   Pfam; PF00646; F-box; 1.
DR   Pfam; PF01827; FTH; 1.
DR   Pfam; PF17906; HTH_48; 1.
DR   SMART; SM00256; FBOX; 1.
DR   PROSITE; PS50181; FBOX; 1.
PE   3: Inferred from homology;
KW   Reference proteome.
FT   CHAIN           1..384
FT                   /note="F-box A protein 224"
FT                   /id="PRO_0000065567"
FT   DOMAIN          71..122
FT                   /note="F-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
SQ   SEQUENCE   384 AA;  44583 MW;  FE9E0D8E1A5A757F CRC64;
     MSAAIRENEL LIRACILYES LDDKPIAESY KNFCRKVGKD IMTLHDFDYW FYRFHNGNHD
     LYHDRSKDPK PKSLSDFPIG VMYDVLGHVD PFERLVLRKV SRNLRDVVQK MRCELDALYV
     NKENTCISIG FGQGTITYSQ VDNGCQVDQW KSSSGYKKKF VEGGDFMELF NTDFRTLLEN
     KKVILNSFDV HHYLLARNGT NEEQFLDHLI EIIKSSNKFT TRSFGIGDLS FDKIARFLEL
     MEPKSLEKLE IGNIIGSTDY DHLVNTEQWK TLKHFISECV EISIPIDHLL HFTTMKVDLT
     ELTVHDALKI RDMLDTSETF DYAMIYVKMT DPIEVARVFN PEYNNDDNQN RLFYYTNPGN
     KKFAIGSSKS MLSISDLASD YFAD