ID   FB341_ARATH             Reviewed;         359 AA.
AC   Q9FGY4; Q8LGH7;
DT   10-AUG-2010, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 113.
DE   RecName: Full=F-box protein At5g49610;
GN   OrderedLocusNames=At5g49610; ORFNames=K6M13.17;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10718197; DOI=10.1093/dnares/7.1.31;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Kotani H.,
RA   Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 5. X. Sequence
RT   features of the regions of 3,076,755 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:31-63(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Quinitio C., Chen H., Kim C.J., Shinn P., Ecker J.R.;
RT   "Arabidopsis ORF clone.";
RL   Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA   Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA   Feldmann K.A.;
RT   "Full-length cDNA from Arabidopsis thaliana.";
RL   Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   INTERACTION WITH SKP1A; SKP1B; ASK11; ASK12; ASK13 AND ASK14.
RX   PubMed=14749489; DOI=10.1093/pcp/pch009;
RA   Takahashi N., Kuroda H., Kuromori T., Hirayama T., Seki M., Shinozaki K.,
RA   Shimada H., Matsui M.;
RT   "Expression and interaction analysis of Arabidopsis Skp1-related genes.";
RL   Plant Cell Physiol. 45:83-91(2004).
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC   -!- SUBUNIT: Part of a SCF (SKP1-cullin-F-box) protein ligase complex (By
CC       similarity). Interacts with SKP1A, SKP1B, ASK11, ASK12, ASK13 and
CC       ASK14. {ECO:0000250, ECO:0000269|PubMed:14749489}.
CC   -!- DOMAIN: The F-box is necessary for the interaction with ASK proteins.
CC       {ECO:0000250}.
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DR   EMBL; AB023033; BAB10775.1; -; Genomic_DNA.
DR   EMBL; CP002688; AED95835.1; -; Genomic_DNA.
DR   EMBL; BT026025; ABG48381.1; -; mRNA.
DR   EMBL; AY084264; AAM60856.1; -; mRNA.
DR   RefSeq; NP_199772.1; NM_124339.3.
DR   AlphaFoldDB; Q9FGY4; -.
DR   SMR; Q9FGY4; -.
DR   BioGRID; 20269; 13.
DR   IntAct; Q9FGY4; 7.
DR   STRING; 3702.AT5G49610.1; -.
DR   PaxDb; Q9FGY4; -.
DR   PRIDE; Q9FGY4; -.
DR   ProteomicsDB; 230798; -.
DR   EnsemblPlants; AT5G49610.1; AT5G49610.1; AT5G49610.
DR   GeneID; 835023; -.
DR   Gramene; AT5G49610.1; AT5G49610.1; AT5G49610.
DR   KEGG; ath:AT5G49610; -.
DR   Araport; AT5G49610; -.
DR   TAIR; locus:2157834; AT5G49610.
DR   eggNOG; ENOG502QW52; Eukaryota.
DR   HOGENOM; CLU_027176_1_2_1; -.
DR   InParanoid; Q9FGY4; -.
DR   OMA; WKEMFSV; -.
DR   OrthoDB; 694741at2759; -.
DR   PhylomeDB; Q9FGY4; -.
DR   UniPathway; UPA00143; -.
DR   PRO; PR:Q9FGY4; -.
DR   Proteomes; UP000006548; Chromosome 5.
DR   ExpressionAtlas; Q9FGY4; baseline and differential.
DR   Genevisible; Q9FGY4; AT.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR017451; F-box-assoc_interact_dom.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   Pfam; PF00646; F-box; 1.
DR   SMART; SM00256; FBOX; 1.
DR   SUPFAM; SSF81383; SSF81383; 1.
DR   TIGRFAMs; TIGR01640; F_box_assoc_1; 1.
DR   PROSITE; PS50181; FBOX; 1.
PE   1: Evidence at protein level;
KW   Reference proteome; Ubl conjugation pathway.
FT   CHAIN           1..359
FT                   /note="F-box protein At5g49610"
FT                   /id="PRO_0000396057"
FT   DOMAIN          3..52
FT                   /note="F-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT   CONFLICT        62
FT                   /note="E -> Q (in Ref. 4; AAM60856)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        152
FT                   /note="K -> R (in Ref. 4; AAM60856)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        243
FT                   /note="R -> K (in Ref. 4; AAM60856)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   359 AA;  41060 MW;  B089505F848B55D7 CRC64;
     MDNQKGALFP DEVILQILAR LPVKSLFRFK SVCKSWYRLP SDKYFTSLFN QLSVKEQLLV
     AEVSDSSSLI CVDNLRGVSE LSLDFVRDRV RIRVSSNGLL CCSSIPEKGV YYVCNPSTRE
     YRKLPKSRER PVTRFYPDGE ATLVGLACDL SKNKFNVVLA GYHRSFGQRP DGSFICLVFD
     SESNKWRKFV SVLEECSFTH MSKNQVVFVN GMLHWLMSGL CYILALDVEH DVWRKISLPD
     EIRIGNGGGN RVYLLESDGF LSVIQLSDVW MKIWKMSEYE TETWSVVDSI SLRCIKGLVP
     GIFPICQTGE YVFLATHKQV LVYQRRSKLW KEMFSVKGSS SLPLWFSAHA FRSTIVPCN