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FB348_ARATH
ID   FB348_ARATH             Reviewed;         778 AA.
AC   Q84V03; Q1PF61; Q94B23; Q9SIW6;
DT   10-AUG-2010, integrated into UniProtKB/Swiss-Prot.
DT   10-AUG-2010, sequence version 2.
DT   25-MAY-2022, entry version 100.
DE   RecName: Full=F-box protein At2g16365;
GN   OrderedLocusNames=At2g16365; ORFNames=F16F14.15;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 2).
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 434-778 (ISOFORM 1).
RC   STRAIN=cv. Columbia;
RX   PubMed=12481096; DOI=10.1104/pp.010207;
RA   Xiao Y.-L., Malik M., Whitelaw C.A., Town C.D.;
RT   "Cloning and sequencing of cDNAs for hypothetical genes from chromosome 2
RT   of Arabidopsis.";
RL   Plant Physiol. 130:2118-2128(2002).
RN   [5]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 447-727 (ISOFORM 3).
RC   STRAIN=cv. Columbia;
RX   PubMed=17147637; DOI=10.1111/j.1467-7652.2006.00183.x;
RA   Underwood B.A., Vanderhaeghen R., Whitford R., Town C.D., Hilson P.;
RT   "Simultaneous high-throughput recombinational cloning of open reading
RT   frames in closed and open configurations.";
RL   Plant Biotechnol. J. 4:317-324(2006).
RN   [6]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 447-778 (ISOFORM 1).
RC   STRAIN=cv. Columbia;
RA   Underwood B.A., Xiao Y.-L., Moskal W.A. Jr., Monaghan E.L., Wang W.,
RA   Redman J.C., Wu H.C., Utterback T., Town C.D.;
RL   Submitted (OCT-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- ALTERNATIVE PRODUCTS:
CC       Event=Alternative splicing; Named isoforms=3;
CC       Name=1;
CC         IsoId=Q84V03-1; Sequence=Displayed;
CC       Name=2;
CC         IsoId=Q84V03-2; Sequence=VSP_039574, VSP_039575;
CC       Name=3;
CC         IsoId=Q84V03-3; Sequence=VSP_039573, VSP_039576;
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAO73431.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR   EMBL; AC007047; AAD22304.2; -; Genomic_DNA.
DR   EMBL; CP002685; AEC06484.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC06485.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC06486.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC06487.1; -; Genomic_DNA.
DR   EMBL; CP002685; ANM61300.1; -; Genomic_DNA.
DR   EMBL; CP002685; ANM61301.1; -; Genomic_DNA.
DR   EMBL; AY042900; AAK68840.1; -; mRNA.
DR   EMBL; BT006598; AAP31942.1; -; mRNA.
DR   EMBL; AY227650; AAO73431.1; ALT_INIT; mRNA.
DR   EMBL; DQ446505; ABE65815.1; -; mRNA.
DR   EMBL; AY773845; AAV63874.1; -; mRNA.
DR   PIR; C84539; C84539.
DR   RefSeq; NP_001118328.1; NM_001124856.2. [Q84V03-1]
DR   RefSeq; NP_001118329.1; NM_001124857.2. [Q84V03-3]
DR   RefSeq; NP_001323527.1; NM_001335470.1. [Q84V03-2]
DR   RefSeq; NP_001323528.1; NM_001335471.1. [Q84V03-2]
DR   RefSeq; NP_671856.2; NM_147321.2. [Q84V03-1]
DR   RefSeq; NP_973716.1; NM_201987.2. [Q84V03-2]
DR   AlphaFoldDB; Q84V03; -.
DR   BioGRID; 1491; 18.
DR   STRING; 3702.AT2G16365.1; -.
DR   PaxDb; Q84V03; -.
DR   PRIDE; Q84V03; -.
DR   ProteomicsDB; 230884; -. [Q84V03-1]
DR   EnsemblPlants; AT2G16365.1; AT2G16365.1; AT2G16365. [Q84V03-1]
DR   EnsemblPlants; AT2G16365.2; AT2G16365.2; AT2G16365. [Q84V03-2]
DR   EnsemblPlants; AT2G16365.3; AT2G16365.3; AT2G16365. [Q84V03-1]
DR   EnsemblPlants; AT2G16365.4; AT2G16365.4; AT2G16365. [Q84V03-3]
DR   EnsemblPlants; AT2G16365.5; AT2G16365.5; AT2G16365. [Q84V03-2]
DR   EnsemblPlants; AT2G16365.6; AT2G16365.6; AT2G16365. [Q84V03-2]
DR   GeneID; 816133; -.
DR   Gramene; AT2G16365.1; AT2G16365.1; AT2G16365. [Q84V03-1]
DR   Gramene; AT2G16365.2; AT2G16365.2; AT2G16365. [Q84V03-2]
DR   Gramene; AT2G16365.3; AT2G16365.3; AT2G16365. [Q84V03-1]
DR   Gramene; AT2G16365.4; AT2G16365.4; AT2G16365. [Q84V03-3]
DR   Gramene; AT2G16365.5; AT2G16365.5; AT2G16365. [Q84V03-2]
DR   Gramene; AT2G16365.6; AT2G16365.6; AT2G16365. [Q84V03-2]
DR   KEGG; ath:AT2G16365; -.
DR   Araport; AT2G16365; -.
DR   TAIR; locus:504956066; AT2G16365.
DR   eggNOG; ENOG502QVXQ; Eukaryota.
DR   HOGENOM; CLU_381014_0_0_1; -.
DR   InParanoid; Q84V03; -.
DR   OMA; HESAWLG; -.
DR   OrthoDB; 731959at2759; -.
DR   PRO; PR:Q84V03; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q84V03; baseline and differential.
DR   Genevisible; Q84V03; AT.
DR   GO; GO:0005634; C:nucleus; IDA:TAIR.
DR   GO; GO:0009658; P:chloroplast organization; IMP:TAIR.
DR   GO; GO:0007623; P:circadian rhythm; IEP:TAIR.
DR   GO; GO:0045893; P:positive regulation of transcription, DNA-templated; IMP:TAIR.
DR   GO; GO:0010099; P:regulation of photomorphogenesis; IGI:TAIR.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR037476; PCH1.
DR   PANTHER; PTHR36062; PTHR36062; 2.
DR   Pfam; PF00646; F-box; 1.
DR   SMART; SM00256; FBOX; 1.
DR   SUPFAM; SSF81383; SSF81383; 1.
PE   2: Evidence at transcript level;
KW   Alternative splicing; Reference proteome.
FT   CHAIN           1..778
FT                   /note="F-box protein At2g16365"
FT                   /id="PRO_0000396064"
FT   DOMAIN          470..505
FT                   /note="F-box"
FT   REGION          74..95
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          186..283
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          316..335
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        74..91
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        212..242
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   VAR_SEQ         455..458
FT                   /note="Missing (in isoform 3)"
FT                   /evidence="ECO:0000303|PubMed:17147637"
FT                   /id="VSP_039573"
FT   VAR_SEQ         455
FT                   /note="S -> R (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:14593172"
FT                   /id="VSP_039574"
FT   VAR_SEQ         456..778
FT                   /note="Missing (in isoform 2)"
FT                   /evidence="ECO:0000303|PubMed:14593172"
FT                   /id="VSP_039575"
FT   VAR_SEQ         515..561
FT                   /note="Missing (in isoform 3)"
FT                   /evidence="ECO:0000303|PubMed:17147637"
FT                   /id="VSP_039576"
SQ   SEQUENCE   778 AA;  88623 MW;  DC34D0EDACE92DF5 CRC64;
     MSEHVMVLGK GNKGISKNSS VNPYESAWLG RWTQSGSEVK FHDGETNCSK QLIRPEDENH
     GVEVLPFPMF KVSQKRETTT TTTTKPSFHE DVGSSSRAMV NRMPWMYPQG ENFSSSNRLD
     FPIQEKTTQN LLELIRPVRI YATVDSVNLP KEDSHQLLKG STVSMKLKGK IFGGYLDLFP
     NQDHSHNRGG VRLQSLESSK DTQEDGPRKN ESSAETNTLE MDRLQTIHLS GSISSSSTKG
     KGIKGYSAIP RTEIPDMNEE PPLVPDRENS VDGHQGETSN SATQSMNVEH FLSRDCKRVR
     LEPEVEASSR WVKRLKTSPS DSSETKSMMK MKEASLGEKE NNNLFLEILK SGINNLQPRN
     QEPVVSQSND LRQGGDDITL LHPWIQRWCK KKTTSTDQPT GQEASFEPES HKEFEKKQYP
     SIAAMALMGK ALSGLNPYGL RKTNSLMVWN ARDLSFTYRS LRWNLTMADW PLLPNDLLEL
     IMGHLETSFE IFLFRSVCSS WRSVVPPLDH SRCLGIKTHD ISFNVGFSFN GRPTNEYCTL
     KKIPIYLVKF WTPFGDDYLL AEMRERNDGE PKLLLSPLSS NGIKYGMGIN KVLFNSLTSP
     IIPFGQYYEI TYIEKRPSEY RFGFPYKLEW VEITERVEFL KLDSEDSRDF AVLFAGRMCN
     LVMYRSRNMS WTQVVEHPEK YAYQDLVAFK GKFYAVDSSG RGRVFVVELS FEVTEIPSVG
     GSQQSSKESL VQSGEELLLV QRFTPVGRRY DEYIYIHGSE CLDLMKKEER ESGFKLMT
 
 
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