FB60_ARATH
ID FB60_ARATH Reviewed; 221 AA.
AC Q9FZ32; B9DG23;
DT 03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 120.
DE RecName: Full=F-box protein At1g55000;
GN OrderedLocusNames=At1g55000; ORFNames=F14C21.53, T24C10.11;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=19423640; DOI=10.1093/dnares/dsp009;
RA Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M.,
RA Shinozaki K.;
RT "Analysis of multiple occurrences of alternative splicing events in
RT Arabidopsis thaliana using novel sequenced full-length cDNAs.";
RL DNA Res. 16:155-164(2009).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP INTERACTION WITH SKP1A/ASK1; SKP1B/ASK2; ASK4; ASK11 AND ASK13.
RX PubMed=12169662; DOI=10.1073/pnas.162339999;
RA Gagne J.M., Downes B.P., Shiu S.-H., Durski A.M., Vierstra R.D.;
RT "The F-box subunit of the SCF E3 complex is encoded by a diverse
RT superfamily of genes in Arabidopsis.";
RL Proc. Natl. Acad. Sci. U.S.A. 99:11519-11524(2002).
CC -!- FUNCTION: Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase
CC complexes, which may mediate the ubiquitination and subsequent
CC proteasomal degradation of target proteins. {ECO:0000250}.
CC -!- PATHWAY: Protein modification; protein ubiquitination.
CC -!- SUBUNIT: Part of a SCF (ASK-cullin-F-box) protein ligase complex (By
CC similarity). Interacts with SKP1A/ASK1, SKP1B/ASK2, ASK4, ASK11 and
CC ASK13. {ECO:0000250, ECO:0000269|PubMed:12169662}.
CC -!- DOMAIN: The F-box is necessary for the interaction with ASK proteins.
CC {ECO:0000250}.
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DR EMBL; AC064840; AAG00879.1; -; Genomic_DNA.
DR EMBL; AC069144; AAG51120.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33171.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33172.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE33173.1; -; Genomic_DNA.
DR EMBL; AF424604; AAL11598.1; -; mRNA.
DR EMBL; AY124829; AAM70538.1; -; mRNA.
DR EMBL; AK316995; BAH19690.1; -; mRNA.
DR EMBL; AK317053; BAH19746.1; -; mRNA.
DR EMBL; AY087755; AAM65291.1; -; mRNA.
DR PIR; E96591; E96591.
DR RefSeq; NP_001031192.1; NM_001036115.1.
DR RefSeq; NP_001031193.1; NM_001036116.2.
DR RefSeq; NP_564673.1; NM_104374.3.
DR AlphaFoldDB; Q9FZ32; -.
DR BioGRID; 27167; 4.
DR IntAct; Q9FZ32; 5.
DR STRING; 3702.AT1G55000.1; -.
DR PaxDb; Q9FZ32; -.
DR PRIDE; Q9FZ32; -.
DR ProteomicsDB; 222425; -.
DR EnsemblPlants; AT1G55000.1; AT1G55000.1; AT1G55000.
DR EnsemblPlants; AT1G55000.2; AT1G55000.2; AT1G55000.
DR EnsemblPlants; AT1G55000.3; AT1G55000.3; AT1G55000.
DR GeneID; 841942; -.
DR Gramene; AT1G55000.1; AT1G55000.1; AT1G55000.
DR Gramene; AT1G55000.2; AT1G55000.2; AT1G55000.
DR Gramene; AT1G55000.3; AT1G55000.3; AT1G55000.
DR KEGG; ath:AT1G55000; -.
DR Araport; AT1G55000; -.
DR TAIR; locus:2011020; AT1G55000.
DR eggNOG; KOG2850; Eukaryota.
DR HOGENOM; CLU_071942_0_0_1; -.
DR InParanoid; Q9FZ32; -.
DR OMA; RTCFIEL; -.
DR OrthoDB; 1259511at2759; -.
DR PhylomeDB; Q9FZ32; -.
DR UniPathway; UPA00143; -.
DR PRO; PR:Q9FZ32; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9FZ32; baseline and differential.
DR Genevisible; Q9FZ32; AT.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProt.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR CDD; cd00118; LysM; 1.
DR Gene3D; 3.10.350.10; -; 1.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR045030; LYSM1-4.
DR InterPro; IPR018392; LysM_dom.
DR InterPro; IPR036779; LysM_dom_sf.
DR PANTHER; PTHR20932; PTHR20932; 1.
DR Pfam; PF12937; F-box-like; 1.
DR Pfam; PF01476; LysM; 1.
DR SMART; SM00257; LysM; 1.
DR SUPFAM; SSF54106; SSF54106; 1.
DR SUPFAM; SSF81383; SSF81383; 1.
DR PROSITE; PS51782; LYSM; 1.
PE 1: Evidence at protein level;
KW Reference proteome; Ubl conjugation pathway.
FT CHAIN 1..221
FT /note="F-box protein At1g55000"
FT /id="PRO_0000283334"
FT DOMAIN 7..46
FT /note="F-box"
FT DOMAIN 74..118
FT /note="LysM"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU01118"
SQ SEQUENCE 221 AA; 24904 MW; 3140E6B7E375A845 CRC64;
MALYCRDTLI IIFQKLTVAD LARASCVCKV WNSVATEDDL VVSAFTAPWR IKELVGRPAS
VSFWRDNGIW KFAISHRICR GDSVTSLAVK YAVQVMDIKR LNNMMSDHGI YSRDRLLIPI
SNPEILANTT CYVELDKYAK REVAVLYLEG APKREQPVPG TNQQSNLSAD GKRRLIESLR
RSMQVDDGTA LYYLAIAEGD PRSALSEFSA DLRWERQAGL N
