AIM3_KLULA
ID AIM3_KLULA Reviewed; 859 AA.
AC Q6CVT9;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 25-MAY-2022, entry version 66.
DE RecName: Full=Altered inheritance of mitochondria protein 3;
GN Name=AIM3; OrderedLocusNames=KLLA0B09460g;
OS Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX NCBI_TaxID=284590;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- SUBCELLULAR LOCATION: Membrane raft {ECO:0000250}; Peripheral membrane
CC protein {ECO:0000250}. Note=Localizes within detergent-insoluble
CC glycolipid-enriched membranes. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the AIM3 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; CR382122; CAH02343.1; -; Genomic_DNA.
DR RefSeq; XP_451950.1; XM_451950.1.
DR AlphaFoldDB; Q6CVT9; -.
DR STRING; 28985.XP_451950.1; -.
DR EnsemblFungi; CAH02343; CAH02343; KLLA0_B09460g.
DR GeneID; 2897066; -.
DR KEGG; kla:KLLA0_B09460g; -.
DR eggNOG; ENOG502S02E; Eukaryota.
DR HOGENOM; CLU_324433_0_0_1; -.
DR InParanoid; Q6CVT9; -.
DR OMA; DNPFRRY; -.
DR Proteomes; UP000000598; Chromosome B.
DR GO; GO:0030479; C:actin cortical patch; IEA:InterPro.
DR GO; GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
DR GO; GO:0051016; P:barbed-end actin filament capping; IEA:InterPro.
DR InterPro; IPR031370; Aim3.
DR Pfam; PF17096; AIM3; 1.
PE 3: Inferred from homology;
KW Membrane; Reference proteome.
FT CHAIN 1..859
FT /note="Altered inheritance of mitochondria protein 3"
FT /id="PRO_0000399601"
FT REGION 38..95
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 137..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 320..358
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 372..624
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 638..859
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 143..159
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 160..179
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 192..290
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 372..440
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 444..460
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..493
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 513..531
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 584..600
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 654..670
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 684..712
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 728..765
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 806..823
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 835..859
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 859 AA; 94317 MW; 7CD4809AA9035266 CRC64;
MSNFWDNNKG SIMSGLASAG KYGYQGTKYV AKAGYKASKT HYNNSQGKKN VEESSDEGYM
SESASDLSHL QDPKMFPPPP LKPGQKQISS DGTVIDAGNA PLVHTAAVPM ANAASHPGLP
PRTPTANSIP MLTQQQTYPP QNMYQQQPPP QPPMQQQVPP QVQQIPQPGQ QLSQQPMQQL
HPEPIPPRNY QTAVETPPQY TPIPSLNAQH VQEQLQQQLQ QQFQPSMGTP DQGQALVQGS
PLASQQQVQP QVQPQTSQYQ SQQVPSPQIQ NQGQLMQQQQ NYFQPQLQQT QPQQYIDSYA
QYQQQGQQQV QPQIQQMQPQ VQQQPIQQPP QAQPQYQQSY PPQYQQQTQS LQPQYQQPVQ
APIVQPPIPQ QDYYQQQQQT PYQPASQPQM YQQQPGQQNP IVSPAPALAQ RPSLSNIQTS
TGHGASQEST VSSTASITVK PYVWMDSDER KEKKKIELQP VSAIDIHQVT PPLHKDRSSS
SSLKSSSRDA SVLEKGKSLS PGPAPLPSRN VRPPTSVDHT KPNTVTPAAA TGTSAEVGDD
QVRPNESITG VYHESTVSFP PPPKPTHNGL PMSPPVSHAR PTVSHKPPNP PRPPVSSKPT
LPPIQTHQRI TSTERAPIGR PKEEVHQAAV LGAYNYNVDV GFAPPPKPPR SMVTSPANDP
QTSLSSRRPS QEYGGVAKAS SRTLPPPPGQ QNGSLPQHTE EEPASNSSES APPAMRMLPL
ADLPPPPQRT DSHTTTSEQP AVPSRTFDPP PRYSTNETIP PTYNIDEDIQ TAHKKPPPKV
PKKKVSLRAG NKPPVPKKKA SLSGTATHEH NESARTSLTQ ETNNSIDDDD DDDSGEGNSF
RKYLRHVVPA ERDHIHKSK
