ID   AIM3_LACTC              Reviewed;         842 AA.
AC   C5DL76;
DT   05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 41.
DE   RecName: Full=Altered inheritance of mitochondria protein 3;
GN   Name=AIM3; OrderedLocusNames=KLTH0F10648g;
OS   Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS   (Yeast) (Kluyveromyces thermotolerans).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Lachancea.
OX   NCBI_TaxID=559295;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX   PubMed=19525356; DOI=10.1101/gr.091546.109;
RG   The Genolevures Consortium;
RA   Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA   Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA   Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA   Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA   Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA   Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA   Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA   Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA   Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA   Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT   "Comparative genomics of protoploid Saccharomycetaceae.";
RL   Genome Res. 19:1696-1709(2009).
CC   -!- SUBCELLULAR LOCATION: Membrane raft {ECO:0000250}; Peripheral membrane
CC       protein {ECO:0000250}. Note=Localizes within detergent-insoluble
CC       glycolipid-enriched membranes. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the AIM3 family. {ECO:0000305}.
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DR   EMBL; CU928170; CAR24227.1; -; Genomic_DNA.
DR   RefSeq; XP_002554664.1; XM_002554618.1.
DR   AlphaFoldDB; C5DL76; -.
DR   STRING; 559295.C5DL76; -.
DR   EnsemblFungi; CAR24227; CAR24227; KLTH0F10648g.
DR   GeneID; 8292876; -.
DR   KEGG; lth:KLTH0F10648g; -.
DR   eggNOG; ENOG502S02E; Eukaryota.
DR   HOGENOM; CLU_324433_0_0_1; -.
DR   InParanoid; C5DL76; -.
DR   OMA; DNPFRRY; -.
DR   OrthoDB; 1315070at2759; -.
DR   Proteomes; UP000002036; Chromosome F.
DR   GO; GO:0030479; C:actin cortical patch; IEA:InterPro.
DR   GO; GO:0045121; C:membrane raft; IEA:UniProtKB-SubCell.
DR   GO; GO:0051016; P:barbed-end actin filament capping; IEA:InterPro.
DR   InterPro; IPR031370; Aim3.
DR   Pfam; PF17096; AIM3; 1.
PE   3: Inferred from homology;
KW   Membrane; Reference proteome.
FT   CHAIN           1..842
FT                   /note="Altered inheritance of mitochondria protein 3"
FT                   /id="PRO_0000399602"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          39..134
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          338..368
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          393..769
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          799..842
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        47..70
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        85..126
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        393..466
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        495..513
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        514..529
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        530..550
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        645..667
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        731..748
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        810..824
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   842 AA;  89574 MW;  9A7238E3FC032A9A CRC64;
     MSDFWDRNKG SIMSGLATAG KQGYKGTKFV AKTGYKAGKQ HYNSSKNKRE GNSNNSSSSD
     LTISSPPPLT ADVSNFPPPP VKPGQNQYHG SSRGGSGNVP PAATSRTSST LPSSYSSEQN
     PIIPQIGNPQ AVPYQVPAPV PQYTTADSQA PHIASRAATI VPGTQLPISS HPNNTAPATY
     NTRPVPLPHR APDNNAAAGL VADPQLLSNT SLPRATRQLL TIDTASIATQ NPNISQEAFA
     VPPANTMASP FPQTTHASYL AASQSPVQPE SIASNKVSEP TPAVPAVPTR TYVRAPAALP
     VQPLPQEERQ AMPQAMPQVM PQAMPQVMPQ AMPQVMPQAM AQTSQPFPEE NGVSDVQELK
     SPTSATTVKP YSWKDSEELK ESLRIKIQNV DISSLPTPPV HRNRSESPSS ETSSLRSKIK
     SRSQSPSGLK SPTQSTAVNL KTTETGKAMS TSRQTPQQTG RSSREGEGAN NGIAGRYDSS
     VQVNFPPPPK PSRSETQTPA NRDMRSSSSP PVKPTTAPRA PPRLPSRSVP SQPPVTSSVP
     KLSSTANGKA DRENIKPKSA VSGAYNYDIK VDFQPPPKPF RKDKESSQQA PRSVPSFEKP
     SKYGPPPASN AETAQGRSIR APPQIPSRAA SLDPPPAYDS SHSHAPSAPP ASNVELQSLS
     ASSIQAGAEK TVKVAGSTIQ IPKTKKAPPI KKALPGSLQA LDTHKSNPEA SAHLTEKGKK
     RPPKPAKKQS LMEQPNKTAS NGGNSRGNFD QELEARLKSR SFHEKPAAVP SLVEHSNSFI
     SSGKIKAAAP PVKPKIPIRL ASNEALQPNE QAEVKDDSDG DNPFRRYLKN AVPSENDRLH
     KN