FBID_COLP3
ID FBID_COLP3 Reviewed; 210 AA.
AC Q47WW8;
DT 05-OCT-2010, integrated into UniProtKB/Swiss-Prot.
DT 13-SEP-2005, sequence version 1.
DT 03-AUG-2022, entry version 83.
DE RecName: Full=3-phospho-D-glycerate guanylyltransferase {ECO:0000255|HAMAP-Rule:MF_02114};
DE Short=3PG guanylyltransferase {ECO:0000255|HAMAP-Rule:MF_02114};
DE EC=2.7.7.106 {ECO:0000255|HAMAP-Rule:MF_02114};
GN Name=fbiD {ECO:0000255|HAMAP-Rule:MF_02114}; OrderedLocusNames=CPS_4046;
OS Colwellia psychrerythraea (strain 34H / ATCC BAA-681) (Vibrio
OS psychroerythus).
OC Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales;
OC Colwelliaceae; Colwellia.
OX NCBI_TaxID=167879;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=34H / ATCC BAA-681;
RX PubMed=16043709; DOI=10.1073/pnas.0504766102;
RA Methe B.A., Nelson K.E., Deming J.W., Momen B., Melamud E., Zhang X.,
RA Moult J., Madupu R., Nelson W.C., Dodson R.J., Brinkac L.M.,
RA Daugherty S.C., Durkin A.S., DeBoy R.T., Kolonay J.F., Sullivan S.A.,
RA Zhou L., Davidsen T.M., Wu M., Huston A.L., Lewis M., Weaver B.,
RA Weidman J.F., Khouri H., Utterback T.R., Feldblyum T.V., Fraser C.M.;
RT "The psychrophilic lifestyle as revealed by the genome sequence of
RT Colwellia psychrerythraea 34H through genomic and proteomic analyses.";
RL Proc. Natl. Acad. Sci. U.S.A. 102:10913-10918(2005).
CC -!- FUNCTION: Guanylyltransferase that catalyzes the activation of (2R)-3-
CC phosphoglycerate (3PG) as 3-[(R)-glyceryl]-diphospho-5'-guanosine, via
CC the condensation of 3PG with GTP. It is involved in the biosynthesis of
CC a derivative of the hydride carrier cofactor coenzyme F420, 3PG-F420.
CC {ECO:0000255|HAMAP-Rule:MF_02114}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(2R)-3-phosphoglycerate + GTP + H(+) = 3-[(R)-glyceryl]-
CC diphospho-5'-guanosine + diphosphate; Xref=Rhea:RHEA:63440,
CC ChEBI:CHEBI:15378, ChEBI:CHEBI:33019, ChEBI:CHEBI:37565,
CC ChEBI:CHEBI:58272, ChEBI:CHEBI:147306; EC=2.7.7.106;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_02114};
CC -!- PATHWAY: Cofactor biosynthesis; coenzyme F420 biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_02114}.
CC -!- SIMILARITY: Belongs to the CofC family. {ECO:0000255|HAMAP-
CC Rule:MF_02114}.
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DR EMBL; CP000083; AAZ28067.1; -; Genomic_DNA.
DR RefSeq; WP_011044784.1; NC_003910.7.
DR AlphaFoldDB; Q47WW8; -.
DR SMR; Q47WW8; -.
DR STRING; 167879.CPS_4046; -.
DR DNASU; 3522326; -.
DR EnsemblBacteria; AAZ28067; AAZ28067; CPS_4046.
DR KEGG; cps:CPS_4046; -.
DR HOGENOM; CLU_076569_1_0_6; -.
DR OMA; HYDEDSY; -.
DR OrthoDB; 1930370at2; -.
DR UniPathway; UPA00071; -.
DR Proteomes; UP000000547; Chromosome.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR GO; GO:0043814; F:phospholactate guanylyltransferase activity; IEA:InterPro.
DR GO; GO:0052645; P:F420-0 metabolic process; IEA:UniProtKB-UniRule.
DR Gene3D; 3.90.550.10; -; 1.
DR HAMAP; MF_02114; CofC; 1.
DR InterPro; IPR002835; CofC.
DR InterPro; IPR029044; Nucleotide-diphossugar_trans.
DR PANTHER; PTHR40392; PTHR40392; 1.
DR Pfam; PF01983; CofC; 1.
DR SUPFAM; SSF53448; SSF53448; 1.
DR TIGRFAMs; TIGR03552; F420_cofC; 1.
PE 3: Inferred from homology;
KW GTP-binding; Nucleotide-binding; Nucleotidyltransferase;
KW Reference proteome; Transferase.
FT CHAIN 1..210
FT /note="3-phospho-D-glycerate guanylyltransferase"
FT /id="PRO_0000398682"
SQ SEQUENCE 210 AA; 23486 MW; 86036E25C0B04436 CRC64;
MRTNIVIPMK DPQLSKTRLD PQLSSRQRQA LALSMFKTTL SFFNKYFPQH HLLVVTASEF
ISDIACTYGA SVLIETKLGL RQAVESAARW SLNNDFQSQL LIPADIAELD YREFERLLMI
YRPVPSVLLC PAFDLGTNAL LTTPPNAIPF LYGIDSSLAH QRVAQERDIV CQVIKLPALA
LDIDTPDDLE LLALLSSPVT QELNKLCKTA
