ID   FBK2_ARATH              Reviewed;         416 AA.
AC   Q9LPW2; F4HNZ0;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   22-FEB-2012, sequence version 2.
DT   03-AUG-2022, entry version 105.
DE   RecName: Full=Putative F-box/kelch-repeat protein At1g12870;
GN   OrderedLocusNames=At1g12870; ORFNames=F13K23.13;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11130712; DOI=10.1038/35048500;
RA   Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA   Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA   Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA   Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA   Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA   Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA   Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA   Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA   Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA   Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA   Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA   Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA   Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA   Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA   Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT   "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL   Nature 408:816-820(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAF78503.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR   EMBL; AC012187; AAF78503.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002684; AEE28941.1; -; Genomic_DNA.
DR   PIR; D86262; D86262.
DR   RefSeq; NP_172747.1; NM_101158.1.
DR   AlphaFoldDB; Q9LPW2; -.
DR   iPTMnet; Q9LPW2; -.
DR   PaxDb; Q9LPW2; -.
DR   PRIDE; Q9LPW2; -.
DR   EnsemblPlants; AT1G12870.1; AT1G12870.1; AT1G12870.
DR   GeneID; 837844; -.
DR   Gramene; AT1G12870.1; AT1G12870.1; AT1G12870.
DR   KEGG; ath:AT1G12870; -.
DR   Araport; AT1G12870; -.
DR   TAIR; locus:2010316; AT1G12870.
DR   HOGENOM; CLU_027176_1_2_1; -.
DR   InParanoid; Q9LPW2; -.
DR   OMA; ASICKRD; -.
DR   OrthoDB; 634455at2759; -.
DR   PRO; PR:Q9LPW2; -.
DR   Proteomes; UP000006548; Chromosome 1.
DR   ExpressionAtlas; Q9LPW2; differential.
DR   GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR   GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IBA:GO_Central.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR   Gene3D; 2.120.10.80; -; 1.
DR   InterPro; IPR006527; F-box-assoc_dom_typ1.
DR   InterPro; IPR017451; F-box-assoc_interact_dom.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR011043; Gal_Oxase/kelch_b-propeller.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   Pfam; PF00646; F-box; 1.
DR   Pfam; PF07734; FBA_1; 1.
DR   SMART; SM00256; FBOX; 1.
DR   SUPFAM; SSF50965; SSF50965; 1.
DR   SUPFAM; SSF81383; SSF81383; 1.
DR   TIGRFAMs; TIGR01640; F_box_assoc_1; 1.
DR   PROSITE; PS50181; FBOX; 1.
PE   4: Predicted;
KW   Kelch repeat; Reference proteome; Repeat.
FT   CHAIN           1..416
FT                   /note="Putative F-box/kelch-repeat protein At1g12870"
FT                   /id="PRO_0000283168"
FT   DOMAIN          27..76
FT                   /note="F-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT   REPEAT          199..243
FT                   /note="Kelch 1"
FT   REPEAT          297..341
FT                   /note="Kelch 2"
SQ   SEQUENCE   416 AA;  48406 MW;  FF9BAC3998DEB0C1 CRC64;
     MVMDEEKQAI VSSSSSSQRK RRYKKLMIAS SSLPDDVVEE IFLKLPVKAL MRFKSLSKQW
     RSTLESCYFS QRHLKIAERS HVDHPKVMII TEKWNPDIEI SFRTISLESV SFLSSALFNF
     PRGFHHPIYA SESCDGIFCI HSPKTQDIYV VNPATRWFRQ LPPARFQIFM HKLNPTLDTL
     RDMIPVNHLA FVKATDYKLV WLYNSDASRV TKCEVFDFKA NAWRYLTCIP SYRIYHDQKP
     ASANGTLYWF TETYNAEIKV IALDIHTEIF RLLPKPSLIA SSEPSHIDMC IIDNSLCMYE
     TEGDKKIIQE IWRLKSSEDA WEKIYTINLL SSSYCHFHVL DGYNLTRLCY WTQKDLVESS
     TPVAIYKDKK IILSHRYTCN LGKRLEVLEL HAKLSNIPCP KASICKRDAL LVHRAI