ID   FBK56_ARATH             Reviewed;         391 AA.
AC   Q9LUQ9;
DT   03-APR-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2000, sequence version 1.
DT   03-AUG-2022, entry version 109.
DE   RecName: Full=F-box/kelch-repeat protein At3g16740;
GN   OrderedLocusNames=At3g16740; ORFNames=MGL6.21;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10819329; DOI=10.1093/dnares/7.2.131;
RA   Sato S., Nakamura Y., Kaneko T., Katoh T., Asamizu E., Tabata S.;
RT   "Structural analysis of Arabidopsis thaliana chromosome 3. I. Sequence
RT   features of the regions of 4,504,864 bp covered by sixty P1 and TAC
RT   clones.";
RL   DNA Res. 7:131-135(2000).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RA   Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA   Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA   Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA   Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA   Shinozaki K.;
RT   "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL   Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN   [5]
RP   INTERACTION WITH ASK11.
RX   PubMed=12169662; DOI=10.1073/pnas.162339999;
RA   Gagne J.M., Downes B.P., Shiu S.-H., Durski A.M., Vierstra R.D.;
RT   "The F-box subunit of the SCF E3 complex is encoded by a diverse
RT   superfamily of genes in Arabidopsis.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:11519-11524(2002).
CC   -!- FUNCTION: Component of SCF(ASK-cullin-F-box) E3 ubiquitin ligase
CC       complexes, which may mediate the ubiquitination and subsequent
CC       proteasomal degradation of target proteins. {ECO:0000250}.
CC   -!- PATHWAY: Protein modification; protein ubiquitination.
CC   -!- SUBUNIT: Part of a SCF (ASK-cullin-F-box) protein ligase complex (By
CC       similarity). Interacts with ASK11. {ECO:0000250,
CC       ECO:0000269|PubMed:12169662}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- DOMAIN: The F-box is necessary for the interaction with ASK proteins.
CC       {ECO:0000250}.
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DR   EMBL; AB022217; BAB02766.1; -; Genomic_DNA.
DR   EMBL; CP002686; AEE75859.1; -; Genomic_DNA.
DR   EMBL; BT004826; AAO44092.1; -; mRNA.
DR   EMBL; AK227738; BAE99722.1; -; mRNA.
DR   RefSeq; NP_566558.1; NM_112547.4.
DR   AlphaFoldDB; Q9LUQ9; -.
DR   BioGRID; 6260; 2.
DR   IntAct; Q9LUQ9; 1.
DR   STRING; 3702.AT3G16740.1; -.
DR   PaxDb; Q9LUQ9; -.
DR   PRIDE; Q9LUQ9; -.
DR   ProteomicsDB; 230931; -.
DR   EnsemblPlants; AT3G16740.1; AT3G16740.1; AT3G16740.
DR   GeneID; 820926; -.
DR   Gramene; AT3G16740.1; AT3G16740.1; AT3G16740.
DR   KEGG; ath:AT3G16740; -.
DR   Araport; AT3G16740; -.
DR   TAIR; locus:2089308; AT3G16740.
DR   HOGENOM; CLU_034692_0_0_1; -.
DR   InParanoid; Q9LUQ9; -.
DR   OMA; FQECAPV; -.
DR   OrthoDB; 634455at2759; -.
DR   PhylomeDB; Q9LUQ9; -.
DR   UniPathway; UPA00143; -.
DR   PRO; PR:Q9LUQ9; -.
DR   Proteomes; UP000006548; Chromosome 3.
DR   ExpressionAtlas; Q9LUQ9; baseline and differential.
DR   Genevisible; Q9LUQ9; AT.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR   GO; GO:0010029; P:regulation of seed germination; IMP:TAIR.
DR   InterPro; IPR006527; F-box-assoc_dom_typ1.
DR   InterPro; IPR017451; F-box-assoc_interact_dom.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   Pfam; PF00646; F-box; 1.
DR   Pfam; PF07734; FBA_1; 1.
DR   SMART; SM00256; FBOX; 1.
DR   SUPFAM; SSF81383; SSF81383; 1.
DR   TIGRFAMs; TIGR01640; F_box_assoc_1; 1.
DR   PROSITE; PS50181; FBOX; 1.
PE   1: Evidence at protein level;
KW   Kelch repeat; Nucleus; Reference proteome; Repeat; Ubl conjugation pathway.
FT   CHAIN           1..391
FT                   /note="F-box/kelch-repeat protein At3g16740"
FT                   /id="PRO_0000283216"
FT   DOMAIN          1..47
FT                   /note="F-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT   REPEAT          104..154
FT                   /note="Kelch 1"
FT   REPEAT          163..215
FT                   /note="Kelch 2"
SQ   SEQUENCE   391 AA;  45548 MW;  CE9BFA60D8206FD9 CRC64;
     MVQISDLPRD LTEEVLSRIP VTSMRAVRFT CKKWNTLSKD RSFTKKHLRG ARAAAKKKQT
     KEFQVIMMIQ FRVYLYSVNL LNPSIERIGK LISLDVEDHV DISKIFHCGG LLLCITKDIS
     RLVVWNPYSG QTRWIKPRNS YHRLDRYALG YEEKNKSCRC YKILRFMDDY EDDRALRLIR
     EFEIYDLNSD SWKVVNVTPD WDVEFYHRGL SLKGNTYWFA QEKLPPLPRG RVITISDMAD
     FLLCFDFTRE RFGPRLPLPF HSFVEDTVTL SSVRDKKLAV LFQPCSASTV KIWISRKIEP
     NAVSWRKVFL AVDMKSLTGF QFDINAASFF VDEKKKVAMV LDKDRFSYKF TRNIAYIIGK
     KGYFEKVDLG ESTVSSCASL VCSYVPSSVQ I