FBK85_ARATH
ID FBK85_ARATH Reviewed; 400 AA.
AC Q8GXF6; O81868;
DT 06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=F-box/kelch-repeat protein At4g19870;
GN OrderedLocusNames=At4g19870; ORFNames=T16H5.230;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617198; DOI=10.1038/47134;
RA Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA Martienssen R., McCombie W.R.;
RT "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL Nature 402:769-777(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
CC -!- SEQUENCE CAUTION:
CC Sequence=CAA19704.1; Type=Erroneous gene model prediction; Note=The predicted gene At4g19870 has been split into 2 genes: At4g19865 and At4g19870.; Evidence={ECO:0000305};
CC Sequence=CAB78989.1; Type=Erroneous gene model prediction; Note=The predicted gene At4g19870 has been split into 2 genes: At4g19865 and At4g19870.; Evidence={ECO:0000305};
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DR EMBL; AL024486; CAA19704.1; ALT_SEQ; Genomic_DNA.
DR EMBL; AL161551; CAB78989.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002687; AEE84237.1; -; Genomic_DNA.
DR EMBL; CP002687; AEE84238.1; -; Genomic_DNA.
DR EMBL; AK118264; BAC42882.1; -; mRNA.
DR PIR; T04768; T04768.
DR RefSeq; NP_193722.2; NM_118107.4.
DR RefSeq; NP_849547.1; NM_179216.2.
DR AlphaFoldDB; Q8GXF6; -.
DR SMR; Q8GXF6; -.
DR PaxDb; Q8GXF6; -.
DR PRIDE; Q8GXF6; -.
DR ProteomicsDB; 230911; -.
DR EnsemblPlants; AT4G19870.1; AT4G19870.1; AT4G19870.
DR EnsemblPlants; AT4G19870.2; AT4G19870.2; AT4G19870.
DR GeneID; 827733; -.
DR Gramene; AT4G19870.1; AT4G19870.1; AT4G19870.
DR Gramene; AT4G19870.2; AT4G19870.2; AT4G19870.
DR KEGG; ath:AT4G19870; -.
DR Araport; AT4G19870; -.
DR TAIR; locus:2133985; AT4G19870.
DR eggNOG; KOG1072; Eukaryota.
DR HOGENOM; CLU_032521_1_2_1; -.
DR InParanoid; Q8GXF6; -.
DR OMA; DSLTCFY; -.
DR OrthoDB; 904448at2759; -.
DR PhylomeDB; Q8GXF6; -.
DR PRO; PR:Q8GXF6; -.
DR Proteomes; UP000006548; Chromosome 4.
DR ExpressionAtlas; Q8GXF6; baseline and differential.
DR Gene3D; 2.120.10.80; -; 1.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001810; F-box_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR Pfam; PF00646; F-box; 1.
DR Pfam; PF01344; Kelch_1; 2.
DR SMART; SM00256; FBOX; 1.
DR SMART; SM00612; Kelch; 2.
DR SUPFAM; SSF117281; SSF117281; 1.
DR SUPFAM; SSF81383; SSF81383; 1.
DR PROSITE; PS50181; FBOX; 1.
PE 2: Evidence at transcript level;
KW Kelch repeat; Reference proteome; Repeat.
FT CHAIN 1..400
FT /note="F-box/kelch-repeat protein At4g19870"
FT /id="PRO_0000274962"
FT DOMAIN 27..73
FT /note="F-box"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT REPEAT 146..192
FT /note="Kelch 1"
FT REPEAT 194..240
FT /note="Kelch 2"
FT REPEAT 242..284
FT /note="Kelch 3"
FT REGION 1..33
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 14..33
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 400 AA; 45081 MW; 5EC4A09C9C2596E4 CRC64;
MKRQAKPPEK KTKRTTNASS PTPSSSSPSL SSLPDEIVEN CLARISRSYY PTLSIVSKSF
RSIISSTELY VARSHLRNTE ECVYVCLSDK SFEFPKWFTL WVNPNQANSM VEKKRKKKKT
IGKLLVPIPS SNLSPVSKSA IAVGSEIYVI GGKVDGALSS AVRILDCRSN TWRDAPSMTV
ARKRPFICLY DGKIYVIGGY NKLSESEPWA EVFDIKTQTW ECLSDPGTEI RNCTIYRIAE
IEGKIHFGYT QKTYAYDPKQ GEWECCEGEV AFPRSQCVME SVLYTFANNY TWEDDYGCKW
WSTDGYGEKV KGLESLLEIH KRNGGSSDNT TKLVACGGKL LLLWEGYMKH NPNNRKKIWC
AVIALEKRDG GKVWGIVEWV DVVHIVPTSC KLLHCLVVSV