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FBK85_ARATH
ID   FBK85_ARATH             Reviewed;         400 AA.
AC   Q8GXF6; O81868;
DT   06-FEB-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=F-box/kelch-repeat protein At4g19870;
GN   OrderedLocusNames=At4g19870; ORFNames=T16H5.230;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617198; DOI=10.1038/47134;
RA   Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T.,
RA   Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B.,
RA   Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M.,
RA   de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M.,
RA   Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D.,
RA   Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J.,
RA   Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B.,
RA   Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J.,
RA   Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R.,
RA   Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M.,
RA   Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P.,
RA   Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S.,
RA   Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C.,
RA   Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J.,
RA   Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S.,
RA   Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A.,
RA   Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M.,
RA   Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M.,
RA   Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D.,
RA   Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E.,
RA   Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S.,
RA   Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R.,
RA   Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M.,
RA   Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E.,
RA   Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P.,
RA   Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K.,
RA   Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K.,
RA   de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K.,
RA   Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M.,
RA   Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G.,
RA   Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K.,
RA   Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K.,
RA   Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W.,
RA   Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H.,
RA   Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B.,
RA   Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J.,
RA   Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K.,
RA   O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N.,
RA   Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A.,
RA   Martienssen R., McCombie W.R.;
RT   "Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
RL   Nature 402:769-777(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=11910074; DOI=10.1126/science.1071006;
RA   Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA   Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA   Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA   Shinagawa A., Shinozaki K.;
RT   "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL   Science 296:141-145(2002).
CC   -!- SEQUENCE CAUTION:
CC       Sequence=CAA19704.1; Type=Erroneous gene model prediction; Note=The predicted gene At4g19870 has been split into 2 genes: At4g19865 and At4g19870.; Evidence={ECO:0000305};
CC       Sequence=CAB78989.1; Type=Erroneous gene model prediction; Note=The predicted gene At4g19870 has been split into 2 genes: At4g19865 and At4g19870.; Evidence={ECO:0000305};
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DR   EMBL; AL024486; CAA19704.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; AL161551; CAB78989.1; ALT_SEQ; Genomic_DNA.
DR   EMBL; CP002687; AEE84237.1; -; Genomic_DNA.
DR   EMBL; CP002687; AEE84238.1; -; Genomic_DNA.
DR   EMBL; AK118264; BAC42882.1; -; mRNA.
DR   PIR; T04768; T04768.
DR   RefSeq; NP_193722.2; NM_118107.4.
DR   RefSeq; NP_849547.1; NM_179216.2.
DR   AlphaFoldDB; Q8GXF6; -.
DR   SMR; Q8GXF6; -.
DR   PaxDb; Q8GXF6; -.
DR   PRIDE; Q8GXF6; -.
DR   ProteomicsDB; 230911; -.
DR   EnsemblPlants; AT4G19870.1; AT4G19870.1; AT4G19870.
DR   EnsemblPlants; AT4G19870.2; AT4G19870.2; AT4G19870.
DR   GeneID; 827733; -.
DR   Gramene; AT4G19870.1; AT4G19870.1; AT4G19870.
DR   Gramene; AT4G19870.2; AT4G19870.2; AT4G19870.
DR   KEGG; ath:AT4G19870; -.
DR   Araport; AT4G19870; -.
DR   TAIR; locus:2133985; AT4G19870.
DR   eggNOG; KOG1072; Eukaryota.
DR   HOGENOM; CLU_032521_1_2_1; -.
DR   InParanoid; Q8GXF6; -.
DR   OMA; DSLTCFY; -.
DR   OrthoDB; 904448at2759; -.
DR   PhylomeDB; Q8GXF6; -.
DR   PRO; PR:Q8GXF6; -.
DR   Proteomes; UP000006548; Chromosome 4.
DR   ExpressionAtlas; Q8GXF6; baseline and differential.
DR   Gene3D; 2.120.10.80; -; 1.
DR   InterPro; IPR036047; F-box-like_dom_sf.
DR   InterPro; IPR001810; F-box_dom.
DR   InterPro; IPR015915; Kelch-typ_b-propeller.
DR   InterPro; IPR006652; Kelch_1.
DR   Pfam; PF00646; F-box; 1.
DR   Pfam; PF01344; Kelch_1; 2.
DR   SMART; SM00256; FBOX; 1.
DR   SMART; SM00612; Kelch; 2.
DR   SUPFAM; SSF117281; SSF117281; 1.
DR   SUPFAM; SSF81383; SSF81383; 1.
DR   PROSITE; PS50181; FBOX; 1.
PE   2: Evidence at transcript level;
KW   Kelch repeat; Reference proteome; Repeat.
FT   CHAIN           1..400
FT                   /note="F-box/kelch-repeat protein At4g19870"
FT                   /id="PRO_0000274962"
FT   DOMAIN          27..73
FT                   /note="F-box"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00080"
FT   REPEAT          146..192
FT                   /note="Kelch 1"
FT   REPEAT          194..240
FT                   /note="Kelch 2"
FT   REPEAT          242..284
FT                   /note="Kelch 3"
FT   REGION          1..33
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        14..33
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   400 AA;  45081 MW;  5EC4A09C9C2596E4 CRC64;
     MKRQAKPPEK KTKRTTNASS PTPSSSSPSL SSLPDEIVEN CLARISRSYY PTLSIVSKSF
     RSIISSTELY VARSHLRNTE ECVYVCLSDK SFEFPKWFTL WVNPNQANSM VEKKRKKKKT
     IGKLLVPIPS SNLSPVSKSA IAVGSEIYVI GGKVDGALSS AVRILDCRSN TWRDAPSMTV
     ARKRPFICLY DGKIYVIGGY NKLSESEPWA EVFDIKTQTW ECLSDPGTEI RNCTIYRIAE
     IEGKIHFGYT QKTYAYDPKQ GEWECCEGEV AFPRSQCVME SVLYTFANNY TWEDDYGCKW
     WSTDGYGEKV KGLESLLEIH KRNGGSSDNT TKLVACGGKL LLLWEGYMKH NPNNRKKIWC
     AVIALEKRDG GKVWGIVEWV DVVHIVPTSC KLLHCLVVSV
 
 
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