FBL12_ARATH
ID FBL12_ARATH Reviewed; 395 AA.
AC Q9SRR1;
DT 23-JAN-2007, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 25-MAY-2022, entry version 113.
DE RecName: Full=F-box/LRR-repeat protein 12;
GN Name=FBL12; OrderedLocusNames=At3g07550; ORFNames=F21O3.26;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130713; DOI=10.1038/35048706;
RA Salanoubat M., Lemcke K., Rieger M., Ansorge W., Unseld M., Fartmann B.,
RA Valle G., Bloecker H., Perez-Alonso M., Obermaier B., Delseny M.,
RA Boutry M., Grivell L.A., Mache R., Puigdomenech P., De Simone V.,
RA Choisne N., Artiguenave F., Robert C., Brottier P., Wincker P.,
RA Cattolico L., Weissenbach J., Saurin W., Quetier F., Schaefer M.,
RA Mueller-Auer S., Gabel C., Fuchs M., Benes V., Wurmbach E., Drzonek H.,
RA Erfle H., Jordan N., Bangert S., Wiedelmann R., Kranz H., Voss H.,
RA Holland R., Brandt P., Nyakatura G., Vezzi A., D'Angelo M., Pallavicini A.,
RA Toppo S., Simionati B., Conrad A., Hornischer K., Kauer G., Loehnert T.-H.,
RA Nordsiek G., Reichelt J., Scharfe M., Schoen O., Bargues M., Terol J.,
RA Climent J., Navarro P., Collado C., Perez-Perez A., Ottenwaelder B.,
RA Duchemin D., Cooke R., Laudie M., Berger-Llauro C., Purnelle B., Masuy D.,
RA de Haan M., Maarse A.C., Alcaraz J.-P., Cottet A., Casacuberta E.,
RA Monfort A., Argiriou A., Flores M., Liguori R., Vitale D., Mannhaupt G.,
RA Haase D., Schoof H., Rudd S., Zaccaria P., Mewes H.-W., Mayer K.F.X.,
RA Kaul S., Town C.D., Koo H.L., Tallon L.J., Jenkins J., Rooney T., Rizzo M.,
RA Walts A., Utterback T., Fujii C.Y., Shea T.P., Creasy T.H., Haas B.,
RA Maiti R., Wu D., Peterson J., Van Aken S., Pai G., Militscher J.,
RA Sellers P., Gill J.E., Feldblyum T.V., Preuss D., Lin X., Nierman W.C.,
RA Salzberg S.L., White O., Venter J.C., Fraser C.M., Kaneko T., Nakamura Y.,
RA Sato S., Kato T., Asamizu E., Sasamoto S., Kimura T., Idesawa K.,
RA Kawashima K., Kishida Y., Kiyokawa C., Kohara M., Matsumoto M., Matsuno A.,
RA Muraki A., Nakayama S., Nakazaki N., Shinpo S., Takeuchi C., Wada T.,
RA Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT "Sequence and analysis of chromosome 3 of the plant Arabidopsis thaliana.";
RL Nature 408:820-822(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=11077244; DOI=10.1016/s1360-1385(00)01769-6;
RA Xiao W., Jang J.-C.;
RT "F-box proteins in Arabidopsis.";
RL Trends Plant Sci. 5:454-457(2000).
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DR EMBL; AC009853; AAF02159.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE74559.1; -; Genomic_DNA.
DR EMBL; CP002686; AEE74560.1; -; Genomic_DNA.
DR EMBL; AK118929; BAC43510.1; -; mRNA.
DR EMBL; BT008530; AAP40357.1; -; mRNA.
DR RefSeq; NP_566312.1; NM_111633.4.
DR RefSeq; NP_850534.1; NM_180203.3.
DR AlphaFoldDB; Q9SRR1; -.
DR SMR; Q9SRR1; -.
DR BioGRID; 5279; 1.
DR IntAct; Q9SRR1; 1.
DR STRING; 3702.AT3G07550.1; -.
DR PaxDb; Q9SRR1; -.
DR ProteomicsDB; 230696; -.
DR EnsemblPlants; AT3G07550.1; AT3G07550.1; AT3G07550.
DR EnsemblPlants; AT3G07550.2; AT3G07550.2; AT3G07550.
DR GeneID; 819944; -.
DR Gramene; AT3G07550.1; AT3G07550.1; AT3G07550.
DR Gramene; AT3G07550.2; AT3G07550.2; AT3G07550.
DR KEGG; ath:AT3G07550; -.
DR Araport; AT3G07550; -.
DR TAIR; locus:2079721; AT3G07550.
DR eggNOG; KOG1947; Eukaryota.
DR HOGENOM; CLU_016072_0_0_1; -.
DR InParanoid; Q9SRR1; -.
DR OMA; CCFGITD; -.
DR OrthoDB; 1046098at2759; -.
DR PhylomeDB; Q9SRR1; -.
DR PRO; PR:Q9SRR1; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9SRR1; baseline and differential.
DR Genevisible; Q9SRR1; AT.
DR GO; GO:0019005; C:SCF ubiquitin ligase complex; IBA:GO_Central.
DR GO; GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR Gene3D; 3.80.10.10; -; 2.
DR InterPro; IPR036047; F-box-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR006553; Leu-rich_rpt_Cys-con_subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR Pfam; PF13516; LRR_6; 3.
DR SMART; SM00367; LRR_CC; 6.
DR SUPFAM; SSF81383; SSF81383; 1.
PE 2: Evidence at transcript level;
KW Leucine-rich repeat; Reference proteome; Repeat.
FT CHAIN 1..395
FT /note="F-box/LRR-repeat protein 12"
FT /id="PRO_0000272252"
FT DOMAIN 13..61
FT /note="F-box"
FT REPEAT 75..100
FT /note="LRR 1"
FT REPEAT 101..126
FT /note="LRR 2"
FT REPEAT 127..152
FT /note="LRR 3"
FT REPEAT 154..177
FT /note="LRR 4"
FT REPEAT 178..203
FT /note="LRR 5"
FT REPEAT 226..250
FT /note="LRR 6"
FT REPEAT 252..278
FT /note="LRR 7"
FT REPEAT 279..304
FT /note="LRR 8"
FT REPEAT 305..330
FT /note="LRR 9"
FT REPEAT 331..356
FT /note="LRR 10"
SQ SEQUENCE 395 AA; 43677 MW; 103B1CEDCC5BAC2F CRC64;
MEDVSESDNN VETSIIHLPD DCLSFIFQRL DSVADHDSFG LTCHRWLNIQ NISRRSLQFQ
CSFSVLNPSS LSQTNPDVSS HHLHRLLTRF QWLEHLSLSG CTVLNDSSLD SLRYPGARLH
TLYLDCCFGI SDDGISTIAS FCPNLSVVSL YRCNISDIGL ETLARASLSL KCVNLSYCPL
VSDFGIKALS QACLQLESVK ISNCKSITGV GFSGCSPTLG YVDADSCQLE PKGITGIISG
GGIEFLNISG VSCYIRKDGL VPIGSGIASK LRILNLRMCR TVGDESIEAI AKGCPLLQEW
NLALCHEVKI SGWEAVGKWC RNLKKLHVNR CRNLCDQGLL ALRCGCMNLQ ILYMNGNARL
TPTAIEMFRL HRADITLRTE EMMVIGPDWR LYAQE
